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Biliverdin, a natural product of heme catabolism, induces tolerance to cardiac allografts

Data up to Jan 2025

Published2004
Citations176
References36

Total Citations Per Year

Abstract

References (36)

Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays

1983 • 52,849 citations

Bilirubin Is an Antioxidant of Possible Physiological Importance

1987 • 3,406 citations

THE HEME OXYGENASE SYSTEM:A Regulator of Second Messenger Gases

1997 • 2,481 citations

Reduced stress defense in heme oxygenase 1-deficient cells

1997 • 1,263 citations

Biliverdin reductase: A major physiologic cytoprotectant

2002 • 1,071 citations

PRIMARILY VASCULARIZED ALLOGRAFTS OF HEARTS IN MICE

1973 • 801 citations

Heme oxygenase: A novel target for the modulation of inflammatory response

1996 • 784 citations

Blocking both signal 1 and signal 2 of T-cell activation prevents apoptosis of alloreactive T cells and induction of peripheral allograft tolerance

1999 • 762 citations

Bilirubin, formed by activation of heme oxygenase-2, protects neurons against oxidative stress injury

1999 • 694 citations

Cardioprotective Actions by a Water-Soluble Carbon Monoxide–Releasing Molecule

2003 • 643 citations

Expression of heme oxygenase-1 can determine cardiac xenograft survival

1998 • 621 citations

A High-Efficiency HeLa Cell Nuclear Transcription Extract

1988 • 612 citations

Quantifying the Frequency of Alloreactive T Cells In Vivo: New Answers to an Old Question

2001 • 519 citations

Haem oxygenase-1 prevents cell death by regulating cellular iron

1999 • 519 citations

Heme oxygenase-1 protects against vascular constriction and proliferation

2001 • 515 citations

Association of low serum concentration of bilirubin with increased risk of coronary artery disease

1994 • 466 citations

Carbon Monoxide Generated by Heme Oxygenase-1 Suppresses the Rejection of Mouse-to-Rat Cardiac Transplants

2001 • 455 citations

Gilbert syndrome and ischemic heart disease: a protective effect of elevated bilirubin levels

2002 • 428 citations

Accommodation of vascularized xenografts: Expression of “protective genes” by donor endothelial cells in a host Th2 cytokine environment

1997 • 428 citations

Heme oxygenase-1-derived bilirubin ameliorates postischemic myocardial dysfunction

2000 • 393 citations

Importance of ICOS–B7RP-1 costimulation in acute and chronic allograft rejection

2001 • 317 citations

Total serum bilirubin and risk of cardiovascular disease in the Framingham offspring study

2001 • 257 citations

Tracking the Immunoregulatory Mechanisms Active During Allograft Tolerance

2002 • 180 citations

Heme oxygenase modulates selectin expression in different regional vascular beds

2000 • 158 citations

SIMPLIFIED MOUSE CERVICAL HEART TRANSPLANTATION USING A CUFF TECHNIQUE

1991 • 114 citations

YY1 transcriptional initiator: Protein interactions and association with a DNA site containing unpaired strands

1996 • 103 citations

Human Biliverdin Reductase Is a Leucine Zipper-like DNA-binding Protein and Functions in Transcriptional Activation of Heme Oxygenase-1 by Oxidative Stress

2002 • 101 citations

Bilirubin Has Widespread Inhibitory Effects on Protein Phosphorylation

1996 • 98 citations

Mode of Inhibitory Action of Bilirubin on Protein Kinase C

1985 • 91 citations

Heme oxygenase‐1, a protective gene that prevents the rejection of transplanted organs

2001 • 83 citations

SUPPRESSOR T CELLS IN RATS WITH PROLONGED CARDIAC ALLOGRAFT SURVIVAL AFTER TREATMENT WITH CYCLOSPORINE1

1984 • 80 citations

Inhibition of NF-κB-Dependent T Cell Activation Abrogates Acute Allograft Rejection

2001 • 64 citations

Intracellular accumulation of unconjugated bilirubin inhibits phytohemagglutinin-induced proliferation and interleukin-2 production of human lymphocytes

1996 • 63 citations

ALLEVIATION OF GRAFT-VERSUS-HOST DISEASE AFTER CONDITIONING WITH COBALT-PROTOPORPHYRIN, AN INDUCER OF HEME OXYGENASE-1

2000 • 43 citations

Unconjugated bilirubin inhibits in vitro cytotoxic T lymphocyte activity of human lymphocytes

1996 • 42 citations

Behavior of helper T lymphocytes in cyclosporine-mediated long-term graft acceptance in the rat

1985 • 7 citations

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Biliverdin, a natural product of heme catabolism, induces tolerance to cardiac allografts (2004) – The FASEB Journal | Metascience Observatory Explorer