Stress Pathways and Heart Failure

The SREBP Pathway: Regulation of Cholesterol Metabolism by Proteolysis of a Membrane-Bound Transcription Factor

1997 • 3,702 citations

A Calcineurin-Dependent Transcriptional Pathway for Cardiac Hypertrophy

1998 • 2,570 citations

Mutations in the gene encoding lamin A/C cause autosomal dominant Emery-Dreifuss muscular dystrophy

1999 • 1,318 citations

MLP-Deficient Mice Exhibit a Disruption of Cardiac Cytoarchitectural Organization, Dilated Cardiomyopathy, and Heart Failure

1997 • 831 citations

Cardiac Function in Mice Overexpressing the β-Adrenergic Receptor Kinase or a βARK Inhibitor

1995 • 714 citations

Loss of a gp130 Cardiac Muscle Cell Survival Pathway Is a Critical Event in the Onset of Heart Failure during Biomechanical Stress

1999 • 666 citations

Signal-Regulated Activation of Serum Response Factor Is Mediated by Changes in Actin Dynamics

1999 • 656 citations

Actin Mutations in Dilated Cardiomyopathy, a Heritable Form of Heart Failure

1998 • 606 citations

Expression of a β-adrenergic receptor kinase 1 inhibitor prevents the development of myocardial failure in gene-targeted mice

1998 • 482 citations

Disruption of the Sarcoglycan–Sarcospan Complex in Vascular Smooth Muscle

1999 • 370 citations

Muscle LIM Protein Promotes Myogenesis by Enhancing the Activity of MyoD

1997 • 286 citations

Requirement of ErbB2 for signalling by interleukin-6 in prostate carcinoma cells

1998 • 282 citations

Severe cardiomyopathy in mice lacking dystrophin and MyoD

1999 • 120 citations

Complexity in simplicity: monogenic disorders and complex cardiomyopathies

1999 • 87 citations

Dystroglycan Versatility

1999 • 48 citations

Genetically engineered mice: Model systems for left ventricular failure

1998 • 26 citations