Spook and Spookier code for stage-specific components of the ecdysone biosynthetic pathway in Diptera

comprehensive molecular insect science

2005 • 1,659 citations

Mutations affecting the pattern of the larval cuticle inDrosophila melanogaster

1984 • 1,546 citations

Mutations affecting the pattern of the larval cuticle inDrosophila melanogaster

1984 • 671 citations

Functional cDNA libraries from Drosophila embryos

1988 • 604 citations

Control and Biochemical Nature of the Ecdysteroidogenic Pathway

2002 • 499 citations

Shade is the Drosophila P450 enzyme that mediates the hydroxylation of ecdysone to the steroid insect molting hormone 20-hydroxyecdysone

2003 • 421 citations

Insect Cytochrome P450

2005 • 414 citations

Drosophila EB1 is important for proper assembly, dynamics, and positioning of the mitotic spindle

2002 • 396 citations

Juvenile hormone acid methyltransferase: A key regulatory enzyme for insect metamorphosis

2003 • 332 citations

Molecular and biochemical characterization of two P450 enzymes in the ecdysteroidogenic pathway of Drosophila melanogaster

2002 • 308 citations

The cytochrome P450 gene superfamily in Drosophila melanogaster : Annotation, intron-exon organization and phylogeny

2001 • 300 citations

The Drosophila disembodied gene controls late embryonic morphogenesis and codes for a cytochrome P450 enzyme that regulates embryonic ecdysone levels

2000 • 292 citations

CYP306A1, a Cytochrome P450 Enzyme, Is Essential for Ecdysteroid Biosynthesis in the Prothoracic Glands of Bombyx and Drosophila

2004 • 288 citations

Regulation of Invasive Cell Behavior by Taiman, a Drosophila Protein Related to AIB1, a Steroid Receptor Coactivator Amplified in Breast Cancer

2000 • 280 citations

Phantom encodes the 25-hydroxylase of Drosophila melanogaster and Bombyx mori: a P450 enzyme critical in ecdysone biosynthesis

2004 • 280 citations

Halloween genes encode P450 enzymes that mediate steroid hormone biosynthesis in Drosophila melanogaster

2004 • 275 citations

Ecdysone response genes govern egg chamber development during mid-oogenesis in Drosophila

1999 • 259 citations

Ecdysone metabolism and distribution during the pupal-adult development of Manduca sexta

1986 • 232 citations

Neverland is an evolutionally conserved Rieske-domain protein that is essential for ecdysone synthesis and insect growth

2006 • 218 citations

The Drosophila ecdysone receptor (EcR) Gene Is Required Maternally for Normal Oogenesis

2000 • 210 citations

Hormonal Control of C. elegans Dauer Formation and Life Span by a Rieske-like Oxygenase

2006 • 189 citations

New Drosophila transgenic reporters: insulated P-element vectors expressing fast-maturing RFP

2004 • 178 citations

Cytochrome P450 CYP307A1/Spook: A regulator for ecdysone synthesis in insects

2005 • 173 citations

Discrete pulses of molting hormone, 20‐hydroxyecdysone, during late larval development of Drosophila melanogaster: Correlations with changes in gene activity

2005 • 169 citations

Essential Roles for Ecdysone Signaling During Drosophila Mid-Embryonic Development

2003 • 169 citations

Ecdysteroid Chemistry and Biochemistry

2011 • 156 citations

Nutritional status affects 20-hydroxyecdysone concentration and progression of oogenesis in Drosophila melanogaster

2005 • 156 citations

Ecdysteroid levels and developmental events during larval moulting in the silkworm, Bombyx mori

1981 • 144 citations

A Drosophila model of the Niemann-Pick type C lysosome storage disease: dnpc1a is required for molting and sterol homeostasis

2005 • 142 citations

APLIP1, a Kinesin Binding JIP-1/JNK Scaffold Protein, Influences the Axonal Transport of Both Vesicles and Mitochondria in Drosophila

2005 • 139 citations

Prothoracicotropic Hormone

2005 • 136 citations

Ecdysteroid Chemistry and Biochemistry

2005 • 130 citations

A role for βFTZ-F1 in regulating ecdysteroid titers during post-embryonic development in Drosophila melanogaster

2005 • 128 citations

Prothoracic gland synthesis of 3-dehydroecdysone and its hemolymph 3β-reductase mediated conversion to ecdysone in representative insects

1990 • 116 citations

Intracellular trafficking by Star regulates cleavage of the Drosophila EGF receptor ligand Spitz

2002 • 116 citations

Identification, characterization and developmental expression of Halloween genes encoding P450 enzymes mediating ecdysone biosynthesis in the tobacco hornworm, Manduca sexta

2006 • 101 citations

Early steps in ecdysteroid biosynthesis: Evidence for the involvement of cytochrome P-450 enzymes

1993 • 98 citations

The crossveinless gene encodes a new member of the Twisted gastrulation family of BMP-binding proteins which, with Short gastrulation, promotes BMP signaling in the crossveins of the Drosophila wing

2005 • 93 citations

Programmed cell death of the prothoracic glands of Manduca sexta during pupal-adult metamorphosis

1997 • 90 citations

Mutations of a Drosophila NPC1 Gene Confer Sterol and Ecdysone Metabolic Defects

2005 • 85 citations

Developmental expression of Manduca shade, the P450 mediating the final step in molting hormone synthesis

2006 • 79 citations

Characterization of duplicated zebrafish cyp19 genes

2001 • 78 citations

Spatial patterns of ecdysteroid receptor activation during the onset ofDrosophilametamorphosis

2002 • 75 citations

Matching catalytic activity to developmental function: Tolloid-related processes Sog in order to help specify the posterior crossvein in theDrosophilawing

2005 • 74 citations

Command and control: regulatory pathways controlling invasive behavior of the border cells

2001 • 66 citations

molting defective is required for ecdysone biosynthesis

2005 • 53 citations

Woc (without children) gene control of ecdysone biosynthesis in Drosophila melanogaster

2001 • 53 citations

Differential incorporation of cholesterol and cholesterol derivatives into ecdysteroids by the larval ring glands and adult ovaries of Drosophila melanogaster: a putative explanation for the l(3)ecd1 mutation

1996 • 48 citations

Phylogeny, expression and enzyme activity of zebrafish cyp19 (P450 aromatase) genes

2001 • 41 citations

Analyses of the CYP11B gene family in the guinea pig suggest the existence of a primordial CYP11B gene with aldosterone synthase activity

2002 • 38 citations

Alternative ESC and ESC-Like Subunits of a Polycomb Group Histone Methyltransferase Complex Are Differentially Deployed during Drosophila Development

2006 • 37 citations

Evidence for the involvement of 3-oxo-Δ4 intermediates in ecdysteroid biosynthesis

1996 • 35 citations

Metabolism in vitro of cholesterol and 25-hydroxycholesterol by the larval prothoracic glands of Manduca sexta

1996 • 31 citations

Paralogues of Porcine Aromatase Cytochrome P450: A Novel Hydroxylase Activity Is Associated with the Survival of a Duplicated Gene

2004 • 28 citations

Stereospecific, mechanism-based, suicide inhibition of a cytochrome P450 involved in ecdysteroid biosynthesis in the prothoracic glands of Manduca sexta

1995 • 25 citations

The hamster adrenal cytochrome P450C11 has equipotent 11β-hydroxylase and 19-hydroxylase activities, but no aldosterone synthase activity

1996 • 23 citations

Isolation of Drosophila Activin and Follistatin cDNAs using novel MACH amplification protocols

2002 • 16 citations