Interleukin 18 inhibits osteoclast formation via T cell production of granulocyte macrophage colony-stimulating factor.
Data up to Jan 2025
Total Citations Per Year
Abstract
References (28)
Cloning of a new cytokine that induces IFN-γ production by T cells
1995 • 2,584 citations
Modulation of Osteoclast Differentiation
1992 • 1,014 citations
OSTEOBLASTIC CELLS ARE INVOLVED IN OSTEOCLAST FORMATION
1988 • 943 citations
Granulocyte/macrophage colony-stimulating factor-deficient mice show no major perturbation of hematopoiesis but develop a characteristic pulmonary pathology.
1994 • 866 citations
Cloning of the cDNA for human IFN-gamma-inducing factor, expression in Escherichia coli, and studies on the biologic activities of the protein.
1996 • 635 citations
Interferon‐γ‐inducing factor enhances T helper 1 cytokine production by stimulated human T cells: synergism with interleukin‐12 for interferon‐γ production
1996 • 606 citations
The Bone Marrow-Derived Stromal Cell Lines MC3T3-G2/PA6 and ST2 Support Osteoclast-Like Cell Differentiation in Cocultures with Mouse Spleen Cells
1989 • 501 citations
Resorption of bone by isolated rabbit osteoclasts
1984 • 423 citations
Cyclosporin-Ain VivoProduces Severe Osteopenia in the Rat: Effect of Dose and Duration of Administration*
1988 • 410 citations
Interleukin 18 together with interleukin 12 inhibits IgE production by induction of interferon-γ production from activated B cells
1997 • 385 citations
Interleukin-18 (Interferon-γ–inducing Factor) Is Produced by Osteoblasts and Acts Via Granulocyte/Macrophage Colony-stimulating Factor and Not Via Interferon-γ to Inhibit Osteoclast Formation
1997 • 381 citations
Hematopoietic and lung abnormalities in mice with a null mutation of the common beta subunit of the receptors for granulocyte-macrophage colony-stimulating factor and interleukins 3 and 5.
1995 • 311 citations
Interleukin-18 Activates NF-κB in Murine T Helper Type 1 Cells
1997 • 192 citations
Mechanisms by which cells of the osteoblast lineage control osteoclast formation and activity
1994 • 172 citations
Histiocytes and histiocytosis [see comments]
1994 • 158 citations
Bone remodelling in human immunodeficiency virus-1-infected patients. A histomorphometric study
1995 • 155 citations
T lymphocytes play a critical role in the development of cyclosporin A-induced osteopenia.
1996 • 111 citations
A role for CD8+ T lymphocytes in osteoclast differentiation in vitro.
1996 • 88 citations
Characterization of mice deficient in interleukin-1β converting enzyme
1997 • 86 citations
Cytokine production and surface antigen expression by peripheral blood mononuclear cells in postmenopausal osteoporosis
1993 • 52 citations
The clonal proliferation of normal mouse hematopoietic cells: enhancement and suppression by colony-stimulating factor combinations
1992 • 46 citations
Cytokines and T-lymphocyte subsets in healthy post-menopausal women: Estrogen retards bone loss without affecting the release of IL-1 or IL-1ra
1997 • 46 citations
Bone mineral metabolism in T lymphocyte–deficient and –replete strains of rat
1995 • 38 citations
T lymphocyte surface antigen markers in osteoporosis
1990 • 34 citations
Thymic Dysfunction in Histiocytosis-X
1987 • 23 citations
Resorption of bone by isolated rabbit osteoclasts
1984 • 21 citations
Histiocytes and Histiocytosis
1998 • 8 citations
The clonal proliferation of normal mouse hematopoietic cells: enhancement and suppression by colony-stimulating factor combinations
1992 • 6 citations