An inactive pool of GSK-3 at the leading edge of growth cones is implicated in Semaphorin 3A signaling

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Specificity and mechanism of action of some commonly used protein kinase inhibitors

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The Molecular Biology of Axon Guidance

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Specificity and mechanism of action of some commonly used protein kinase inhibitors

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Molecular cloning and expression of glycogen synthase kinase-3/factor A.

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Lithium inhibits glycogen synthase kinase-3 activity and mimics Wingless signalling in intact cells

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Collapsin: A protein in brain that induces the collapse and paralysis of neuronal growth cones

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Role of Glycogen Synthase Kinase-3 in the Phosphatidylinositol 3-Kinase/Akt Cell Survival Pathway

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Polarization of Chemoattractant Receptor Signaling During Neutrophil Chemotaxis

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A Cell's Sense of Direction

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Inactivation of glycogen synthase kinase-3β by phosphorylation: new kinase connections in insulin and growth-factor signalling

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Selective small molecule inhibitors of glycogen synthase kinase-3 modulate glycogen metabolism and gene transcription

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Decreased nuclear beta-catenin, tau hyperphosphorylation and neurodegeneration in GSK-3beta conditional transgenic mice

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Glycogen synthase kinase-3 induces Alzheimer's disease-like phosphorylation of tau: Generation of paired helical filament epitopes and neuronal localisation of the kinase

1992 • 709 citations

Collapsin-induced growth cone collapse mediated by an intracellular protein related to UNC-33

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A Common Phosphate Binding Site Explains the Unique Substrate Specificity of GSK3 and Its Inactivation by Phosphorylation

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Crystal Structure of Glycogen Synthase Kinase 3β

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Modulation of the glycogen synthase kinase-3 family by tyrosine phosphorylation.

1993 • 616 citations

Mitogen inactivation of glycogen synthase kinase-3β in intact cells via serine 9 phosphorylation

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Glycogen synthase kinase‐3 and the Alzheimer‐like state of microtubule‐associated protein tau

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Sernaphorin III can function as a selective chemorepellent to pattern sensory projections in the spinal cord

1995 • 492 citations

Glycogen synthase kinase-3 and dorsoventral patterning in Xenopus embryos

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Neuropilin-1 Mediates Collapsin-1/Semaphorin III Inhibition of Endothelial Cell Motility

1999 • 469 citations

Alzheimer's disease-like phosphorylation of the microtubule-associated protein tau by glycogen synthase kinase-3 in transfected mammalian cells

1994 • 461 citations

Chemoattractant-mediated transient activation and membrane localization of Akt/PKB is required for efficient chemotaxis to cAMP in Dictyostelium

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wingless signaling acts through zeste-white 3, the drosophila homolog of glycogen synthase kinase-3, to regulate engrailed and establish cell fate

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Wingless inactivates glycogen synthase kinase-3 via an intracellular signalling pathway which involves a protein kinase C.

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Rac1 Mediates Collapsin-1-Induced Growth Cone Collapse

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Selective small-molecule inhibitors of glycogen synthase kinase-3 activity protect primary neurones from death

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Phosphorylation of cofilin by LIM-kinase is necessary for semaphorin 3A-induced growth cone collapse

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Critical role for the docking-protein FRS2α in FGF receptor-mediated signal transduction pathways

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Glycogen synthase kinase 3β phosphorylation of microtubule-associated protein 1B regulates the stability of microtubules in growth cones

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Evidence that Lithium Alters Phosphoinositide Metabolism: Chronic Administration Elevates Primarily <scp>d</scp>‐myo‐Inositol‐1‐Phosphate in Cerebral Cortex of the Rat

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The organization of F-actin and microtubules in growth cones exposed to a brain-derived collapsing factor.

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Regulation of Spemann organizer formation by the intracellular kinase Xgsk-3

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Evidence for collapsin-1 functioning in the control of neural crest migration in both trunk and hindbrain regions

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Developmental expression and localization of glycogen synthase kinase-3β in rat brain

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Semaphorin 3A–Vascular Endothelial Growth Factor-165 Balance Mediates Migration and Apoptosis of Neural Progenitor Cells by the Recruitment of Shared Receptor

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Inactivation of Glycogen Synthase Kinase-3 by Epidermal Growth Factor Is Mediated by Mitogen-activated Protein Kinase/p90 Ribosomal Protein S6 Kinase Signaling Pathway in NIH/3T3 Cells

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A novel gene family defined by human dihydropyrimidinase and three related proteins with differential tissue distribution

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Semaphorin3a Enhances Endocytosis at Sites of Receptor–F-Actin Colocalization during Growth Cone Collapse

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Glycogen synthase kinase-3β phosphorylates tau protein at multiple sites in intact cells

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Myelin and Collapsin-1 Induce Motor Neuron Growth Cone Collapse through Different Pathways: Inhibition of Collapse by Opposing Mutants of Rac1

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CAMs and Axonal Growth: A Critical Evaluation of the Role of Calcium and the MAPK Cascade

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The Neurite Retraction Induced by Lysophosphatidic Acid Increases Alzheimer's Disease-like Tau Phosphorylation

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The mechanism by which epidermal growth factor inhibits glycogen synthase kinase 3 in A431 cells

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Sema3A-induced growth-cone collapse is mediated by Rac1 amino acids 17–32

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Localization and Developmental Changes of τ Protein Kinase I/Glycogen Synthase Kinase‐3β in Rat Brain

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Expression analysis of glycogen synthase kinase‐3 in human tissues

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The inhibition of phosphatidylinositol‐3‐kinase induces neurite retraction and activates GSK3

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Tyrosine dephosphorylation of glycogen synthase kinase‐3 is involved in its extracellular signal‐dependent inactivation

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The control of beta-catenin and TCF during embryonic development and cancer.

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Regulation of Ribosomal S6 Protein Kinase-p90^rsk, Glycogen Synthase Kinase 3, and β-Catenin in Early Xenopus Development

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Overexpressed tau protein in cultured cells is phosphorylated without formation of PHF: implication of phosphoprotein phosphatase involvement

1995 • 59 citations

Implication of cyclin-dependent kinases and glycogen synthase kinase 3 in the phosphorylation of microtubule-associated protein 1B in developing neuronal cells

1998 • 50 citations

Distribution of tau protein kinase I/glycogen synthase kinase-3β, phosphatases 2A and 2B, and phosphorylated tau in the developing rat brain

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Differential Cytoskeletal Changes during Growth Cone Collapse in Response to hSema III and Thrombin

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Structural Features of Collapsin Required for Biological Activity and Distribution of Binding Sites in the Developing Chick

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