Brain-Derived Neurotrophic Factor Regulates Hedonic Feeding by Acting on the Mesolimbic Dopamine System

Essential Role of BDNF in the Mesolimbic Dopamine Pathway in Social Defeat Stress

2006 • 1,997 citations

Brain dopamine and obesity

2001 • 1,817 citations

Distribution of Brain-Derived Neurotrophic Factor (BDNF) Protein and mRNA in the Normal Adult Rat CNS: Evidence for Anterograde Axonal Transport

1997 • 1,093 citations

‘Liking’ and ‘wanting’ food rewards: Brain substrates and roles in eating disorders

2009 • 1,044 citations

The Reward Deficiency Syndrome: A Biogenetic Model for the Diagnosis and Treatment of Impulsive, Addictive and Compulsive Behaviors

2000 • 929 citations

Ghrelin modulates the activity and synaptic input organization of midbrain dopamine neurons while promoting appetite

2006 • 922 citations

Leptin Receptor Signaling in Midbrain Dopamine Neurons Regulates Feeding

2006 • 872 citations

Brain-derived neurotrophic factor regulates energy balance downstream of melanocortin-4 receptor

2003 • 858 citations

Brain-derived neurotrophic factor-deficient mice develop aggressiveness and hyperphagia in conjunction with brain serotonergic abnormalities

1999 • 825 citations

BDNF regulates eating behavior and locomotor activity in mice

2000 • 788 citations

Conditional Deletion Of Brain-Derived Neurotrophic Factor in the Postnatal Brain Leads to Obesity and Hyperactivity

2001 • 738 citations

Leptin Regulation of the Mesoaccumbens Dopamine Pathway

2006 • 615 citations

Feeding-induced dopamine release in dorsal striatum correlates with meal pleasantness ratings in healthy human volunteers

2003 • 608 citations

BDNF controls dopamine D3 receptor expression and triggers behavioural sensitization

2001 • 557 citations

Reward drive and rash impulsiveness as dimensions of impulsivity: Implications for substance misuse

2004 • 467 citations

Hyperphagia, Severe Obesity, Impaired Cognitive Function, and Hyperactivity Associated With Functional Loss of One Copy of the Brain-Derived Neurotrophic Factor (BDNF) Gene

2006 • 460 citations

Differential responsiveness of dopamine transmission to food-stimuli in nucleus accumbens shell/core compartments

1999 • 433 citations

Immunocytochemical localization of TrkB in the central nervous system of the adult rat

1997 • 426 citations

Dynamic BDNF activity in nucleus accumbens with cocaine use increases self-administration and relapse

2007 • 401 citations

Deficits of mesolimbic dopamine neurotransmission in rat dietary obesity

2009 • 376 citations

Differential Influence of Associative and Nonassociative Learning Mechanisms on the Responsiveness of Prefrontal and Accumbal Dopamine Transmission to Food Stimuli in Rats FedAd Libitum

1997 • 374 citations

Selective Deletion ofBdnfin the Ventromedial and Dorsomedial Hypothalamus of Adult Mice Results in Hyperphagic Behavior and Obesity

2007 • 355 citations

Dopamine Production in the Caudate Putamen Restores Feeding in Dopamine-Deficient Mice

2001 • 345 citations

Local gene knockdown in the brain using viral-mediated RNA interference

2003 • 342 citations

The Hypothalamic Neuropeptide Melanin-Concentrating Hormone Acts in the Nucleus Accumbens to Modulate Feeding Behavior and Forced-Swim Performance

2005 • 339 citations

Brain-Derived Neurotrophic Factor and Obesity in the WAGR Syndrome

2008 • 329 citations

Brain-Derived Neurotrophic Factor Is Required for the Establishment of the Proper Number of Dopaminergic Neurons in the Substantia Nigra Pars Compacta

2005 • 296 citations

Dopaminergic neurons in rat ventral midbrain express brain‐derived neurotrophic factor and neurotrophin‐3 mRNAs

1994 • 290 citations

The role of dopamine in motivation for food in humans: implications for obesity

2002 • 281 citations

Feeding behavior in dopamine-deficient mice

1999 • 233 citations

Dopaminergic Supersensitivity in G Protein-Coupled Receptor Kinase 6-Deficient Mice

2003 • 222 citations

Adeno-associated virus vectors serotyped with AAV8 capsid are more efficient than AAV-1 or -2 serotypes for widespread gene delivery to the neonatal mouse brain

2006 • 195 citations

A dopamine‐μ₁ opioid link in the rat ventral tegmentum shared by palatable food (Fonzies) and non‐psychostimulant drugs of abuse

1998 • 195 citations

Conditional Deletion Of Brain-Derived Neurotrophic Factor in the Postnatal Brain Leads to Obesity and Hyperactivity

2001 • 187 citations

Brain-Derived Neurotrophic Factor Plays a Role as an Anorexigenic Factor in the Dorsal Vagal Complex

2005 • 155 citations

Dopaminergic Agonists Normalize Elevated Hypothalamic Neuropeptide Y and Corticotropin-Releasing Hormone, Body Weight Gain, and Hyperglycemia in ob/ob Mice

2000 • 148 citations

Expression of trkB andtrkC mRNAs by adult midbrain dopamine neurons: A double-label in situ hybridization study

1999 • 140 citations

Dopamine-Deficient Mice Are Hypersensitive to Dopamine Receptor Agonists

2000 • 139 citations

Dopamine is required for hyperphagia in Lepob/ob mice

2000 • 136 citations

Examination of behavioral deficits triggered by targeting BDNF in fetal or postnatal brains of mice

2006 • 129 citations

BDNF-dependent synaptic sensitization in midbrain dopamine neurons after cocaine withdrawal

2006 • 129 citations

Bingeing, Self‐restriction, and Increased Body Weight in Rats With Limited Access to a Sweet‐fat Diet

2008 • 117 citations

Tropomyosin-Related Kinase B in the Mesolimbic Dopamine System: Region-Specific Effects on Cocaine Reward

2008 • 113 citations

Influence of Methylphenidate on Eating in Obese Men

2004 • 103 citations

Binge Eating in Rats with Limited Access to Vegetable Shortening

2006 • 81 citations

Palatable food induces an appetitive behaviour in satiated rats which can be inhibited by chronic stress

1997 • 76 citations

Diminished hypothalamic bdnf expression and impaired VMH function are associated with reduced SF‐1 gene dosage

2006 • 74 citations

Meal patterns of free feeding rats treated with clozapine, olanzapine, or haloperidol

2002 • 69 citations

ΔFosB-Mediated Alterations in Dopamine Signaling Are Normalized by a Palatable High-Fat Diet

2008 • 66 citations

Severe deficits in 5‐HT_2A‐mediated neurotransmission in BDNF conditional mutant mice

2006 • 62 citations

Comparison of hydrogenated vegetable shortening and nutritionally complete high-fat diet on limited access-binge behavior in rats

2007 • 55 citations

Tyrosine kinase B and C receptors in the neostriatum and nucleus accumbens are co-localized in enkephalin-positive and enkephalin-negative neuronal profiles and their expression is influenced by cocaine

2003 • 43 citations

Hyperphagia induced by GABAA receptor-mediated inhibition of the nucleus accumbens shell: Dependence on intact neural output from the central amygdaloid region.

2005 • 42 citations

Plasticity of Quantal Size in Ventral Midbrain Dopamine Neurons: Possible Implications for the Neurochemistry of Feeding and Reward

1998 • 27 citations