Comparison of prospective and retrospective methods for haplotype inference in case-control studies

Maximum-likelihood estimation of molecular haplotype frequencies in a diploid population.

1995 • 1,977 citations

Score Tests for Association between Traits and Haplotypes when Linkage Phase Is Ambiguous

2002 • 1,798 citations

Maximum likelihood estimation via the ECM algorithm: A general framework

1993 • 1,721 citations

Logistic disease incidence models and case-control studies

1979 • 1,064 citations

Testing Association of Statistically Inferred Haplotypes with Discrete and Continuous Traits in Samples of Unrelated Individuals

2002 • 677 citations

An E-M algorithm and testing strategy for multiple-locus haplotypes.

1995 • 544 citations

Estimation and Tests of Haplotype-Environment Interaction when Linkage Phase Is Ambiguous

2003 • 438 citations

On the advantage of haplotype analysis in the presence of multiple disease susceptibility alleles

2002 • 366 citations

HAPLO: A Program Using the EM Algorithm to Estimate the Frequencies of Multi-site Haplotypes

1995 • 331 citations

Inference on Haplotype Effects in Case-Control Studies Using Unphased Genotype Data

2003 • 254 citations

Modeling and E-M Estimation of Haplotype-Specific Relative Risks from Genotype Data for a Case-Control Study of Unrelated Individuals

2003 • 253 citations

On Generalized Score Tests

1992 • 231 citations

A Method for the Assessment of Disease Associations with Single-Nucleotide Polymorphism Haplotypes and Environmental Variables in Case-Control Studies

2003 • 174 citations

Mapping Genes for NIDDM: Design of the Finland—United States Investigation of NIDDM Genetics (FUSION) Study

1998 • 97 citations

Estimating haplotype frequencies and standard errors for multiple single nucleotide polymorphisms

2003 • 85 citations

On Generalized Score Tests

1992 • 73 citations

Prospective Analysis of Logistic Case-Control Studies

1995 • 72 citations