Effects of immunosuppressive therapy on expression of inducible nitric oxide synthase (iNOS) during cardiac allograft rejection

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

The L-Arginine-Nitric Oxide Pathway

1993 • 6,737 citations

Nitric oxide as a secretory product of mammalian cells

1992 • 4,437 citations

Nitric oxide. A macrophage product responsible for cytostasis and respiratory inhibition in tumor target cells.

1989 • 1,747 citations

Improved technique of heart transplantation in rats

1969 • 1,338 citations

Biosynthesis and Metabolism of Endothelium-Derived Nitric Oxide

1990 • 1,284 citations

Mammalian nitrate biosynthesis: mouse macrophages produce nitrite and nitrate in response to Escherichia coli lipopolysaccharide.

1985 • 1,146 citations

Nitric oxide, a novel biologic messenger

1992 • 754 citations

Production of hydroxyl radicals from the simultaneous generation of superoxide and nitric oxide

1992 • 702 citations

Control of cardiac muscle cell function by an endogenous nitric oxide signaling system.

1993 • 656 citations

Interferon‐γ and tumor necrosis factor induce the L‐arginine‐dependent cytotoxic effector mechanism in murine macrophages^*

1988 • 511 citations

Abnormal contractile function due to induction of nitric oxide synthesis in rat cardiac myocytes follows exposure to activated macrophage-conditioned medium.

1993 • 457 citations

Cytokine-inducible nitric oxide synthase (iNOS) expression in cardiac myocytes. Characterization and regulation of iNOS expression and detection of iNOS activity in single cardiac myocytes in vitro.

1994 • 436 citations

Nitric oxide production within cardiac myocytes reduces their contractility in endotoxemia

1992 • 327 citations

Activated macrophages kill pancreatic syngeneic islet cells via arginine-dependent nitric oxide generation

1991 • 257 citations

The lethal effects of cytokine-induced nitric oxide on cardiac myocytes are blocked by nitric oxide synthase antagonism or transforming growth factor beta.

1995 • 251 citations

Alloantigen-induced activation of rat splenocytes is regulated by the oxidative metabolism of L-arginine.

1990 • 230 citations

Induction of myocardial nitric oxide synthase by cardiac allograft rejection.

1994 • 212 citations

Modulation of in vivo alloreactivity by inhibition of inducible nitric oxide synthase.

1995 • 208 citations

EPR detection of heme and nonheme iron-containing protein nitrosylation by nitric oxide during rejection of rat heart allograft.

1992 • 195 citations

Nitric oxide production in host-versus-graft and graft-versus-host reactions in the rat.

1992 • 179 citations

Nitric oxide synthase in cultured endocardial cells of the pig

1991 • 164 citations

CYTOKINE GENE EXPRESSION IN REJECTING CARDIAC ALLOGRAFTS

1992 • 106 citations

Nitric oxide modulates vascular permeability in the rat coronary circulation

1993 • 75 citations

EVIDENCE THAT NITRIC OXIDE PRODUCTION BY IN VIVO ALLOSENSITIZED CELLS INHIBITS THE DEVELOPMENT OF ALLOSPECIFIC CTL

1992 • 75 citations

Nitric oxide synthesis in the in vivo allograft response: a possible regulatory mechanism.

1991 • 71 citations

T-cell-mediated activation of macrophages

1991 • 71 citations

Localization of inducible nitric oxide synthase in acute renal allograft rejection in the rat.

1994 • 49 citations

URINARY NITRATE EXCRETION IS A NONINVASIVE INDICATOR OF ACUTE CARDIAC ALLOGRAFT REJECTION AND NITRIC OXIDE PRODUCTION IN THE RAT

1994 • 47 citations

T cells in autoimmunity and allograft rejection.

1994 • 13 citations