Knockdown of Hepatic ABCA1 by RNA Interference Decreases Plasma HDL Cholesterol Levels and Influences Postprandial Lipemia in Mice

Killing the messenger: short RNAs that silence gene expression

2003 • 1,197 citations

siRNAs: applications in functional genomics and potential as therapeutics

2004 • 903 citations

siRNA-mediated gene silencing in vitro and in vivo

2002 • 880 citations

High Density Lipoproteins and Arteriosclerosis

2001 • 694 citations

RNAi suppresses polyglutamine-induced neurodegeneration in a model of spinocerebellar ataxia

2004 • 653 citations

Specific Binding of ApoA-I, Enhanced Cholesterol Efflux, and Altered Plasma Membrane Morphology in Cells Expressing ABC1

2000 • 568 citations

PGC-1 promotes insulin resistance in liver through PPAR-α-dependent induction of TRB-3

2004 • 545 citations

High density lipoprotein deficiency and foam cell accumulation in mice with targeted disruption of ATP-binding cassette transporter-1

2000 • 543 citations

Molecular Cloning of the Human ATP-Binding Cassette Transporter 1 (hABC1): Evidence for Sterol-Dependent Regulation in Macrophages

1999 • 502 citations

Transport of lipids from Golgi to plasma membrane is defective in Tangier disease patients and Abc1-deficient mice

2000 • 477 citations

ABCA1 Is Required for Normal Central Nervous System ApoE Levels and for Lipidation of Astrocyte-secreted apoE

2004 • 423 citations

Increased Atherosclerosis in Hyperlipidemic Mice With Inactivation of ABCA1 in Macrophages

2002 • 390 citations

Deficiency of ABCA1 Impairs Apolipoprotein E Metabolism in Brain

2004 • 354 citations

Monocyte/macrophage expression of ABCA1 has minimal contribution to plasma HDL levels

2001 • 261 citations

HDL Apolipoproteins and ABCA1

2003 • 245 citations

Role of the hepatic ABCA1 transporter in modulating intrahepatic cholesterol and plasma HDL cholesterol concentrations

2003 • 225 citations

ABCA1 overexpression leads to hyperalphalipoproteinemia and increased biliary cholesterol excretion in transgenic mice

2001 • 204 citations

Human ABCA1 BAC Transgenic Mice Show Increased High Density Lipoprotein Cholesterol and ApoAI-dependent Efflux Stimulated by an Internal Promoter Containing Liver X Receptor Response Elements in Intron 1

2001 • 199 citations

ABCA1-Deficient Mice

2003 • 149 citations

Cholesterol efflux regulatory protein, Tangier disease and familial high-density lipoprotein deficiency

2000 • 120 citations

Recycling of Apoprotein E Is Associated with Cholesterol Efflux and High Density Lipoprotein Internalization

2003 • 100 citations

Alterations of plasma lipids in mice via adenoviral-mediated hepatic overexpression of human ABCA1

2003 • 99 citations

Regulation and Activity of the Human ABCA1 Gene in Transgenic Mice

2001 • 94 citations

Imaging and tissue biodistribution of 99mTc-labeled adenovirus knob (serotype 5)

1998 • 89 citations

Rapid quantification of murine ABC mRNAs by real time reverse transcriptase-polymerase chain reaction

2002 • 39 citations

Differential RNA interference: replacement of endogenous with recombinant low density lipoprotein receptor-related protein (LRP)

2004 • 18 citations

Simultaneous Insertion of Two Expression Cassettes into Adenovirus Vectors

2001 • 7 citations