Properties of D2 dopamine receptor autoradiography: High percentage of high-affinity agonist sites and increased nucleotide sensitivity in tissue sections

Relationship between the inhibition constant (KI) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reaction

1973 • 12,522 citations

EVIDENCE FOR THE EXISTENCE OF MONOAMINE-CONTAINING NEURONS IN THE CENTRAL NERVOUS SYSTEM. I. DEMONSTRATION OF MONOAMINES IN THE CELL BODIES OF BRAIN STEM NEURONS.

1964 • 5,110 citations

Brain dopamine receptors.

1980 • 1,878 citations

Two dopamine receptors: Biochemistry, physiology and pharmacology

1984 • 939 citations

Central Catecholamine Neuron Systems: Anatomy and Physiology of the Dopamine Systems

1978 • 920 citations

A new method for receptor autoradiography: [3H]Opioid receptors in rat brain

1979 • 797 citations

Principles of Drug Action: The Basis of Pharmacology.

1975 • 616 citations

A quantitative analysis of beta-adrenergic receptor interactions: resolution of high and low affinity states of the receptor by computer modeling of ligand binding data.

1980 • 545 citations

Quantitative receptor autoradiography using [3H]Ultrofilm: application to multiple benzodiazepine receptors

1982 • 529 citations

Mesencephalic dopamine neurons projecting to neocortex

1974 • 503 citations

Light microscopic localization of brain opiate receptors: a general autoradiographic method which preserves tissue quality

1982 • 466 citations

The Classification of Dopamine Receptors: Relationship to Radioligand Binding

1983 • 392 citations

Quantitative autoradiographic distribution of L-[3H]glutamate-binding sites in rat central nervous system

1984 • 353 citations

Evidence for the absence of impulse-regulating somatodendritic and synthesis-modulating nerve terminal autoreceptors on subpopulations of mesocortical dopamine neurons

1984 • 312 citations

Anterior pituitary dopamine receptors. Demonstration of interconvertible high and low affinity states of the D-2 dopamine receptor.

1982 • 295 citations

Specificity of 6-hydroxydopamine induced degeneration of central monoamine neurones: An electron and fluorescence microscopic study with special reference to intracerebral injection on the nigro-striatal dopamine system

1973 • 295 citations

Quantitative resolution of beta-adrenergic receptor subtypes by selective ligand binding: application of a computerized model fitting technique.

1979 • 220 citations

[3H]Spiperone binding sites in brain: autoradiographic localization of multiple receptors

1981 • 210 citations

Effect of guanine nucleotides on striatal dopamine receptors

1978 • 186 citations

Dopamine Receptor Parameters Detected by [³H]Spiperone Depend on Tissue Concentration: Analysis and Examples

1984 • 173 citations

Changes in [3H]muscimol binding in substantia nigra, entopeduncular nucleus, globus pallidus, and thalamus after striatal lesions as demonstrated by quantitative receptor autoradiography

1983 • 169 citations

Dopamine receptor of the porcine anterior pituitary gland. Evidence for two affinity states discriminated by both agonists and antagonists.

1982 • 158 citations

Quantitative receptor autoradiography with tritium-labeled ligands: comparison of biochemical and densitometric measurements

1984 • 155 citations

Complete Conversion of Brain D₂ Dopamine Receptors from the High‐ to the Low‐Affinity State for Dopamine Agonists, Using Sodium Ions and Guanine Nucleotide

1985 • 139 citations

Dopamine receptor binding regulated by guanine nucleotides.

1979 • 111 citations

Brain Dopamine and Serotonin Receptor Sites Revealed by Digital Subtraction Autoradiography

1985 • 106 citations

Computer-assisted video analysis of [3H]spiroperidol binding autoradiographs

1984 • 93 citations

Quantitative analysis of [3H]spiroperidol binding to rat forebrain sections: Plasticity of neostriatal dopamine receptors after nigrostriatal injury

1984 • 90 citations

Anomalous properties of [3H]spiperone binding sites in various areas of the rat limbic system.

1979 • 90 citations

Agonist high- and low-affinity states of the D2-dopamine receptor in calf brain. Partial conversion by guanine nucleotide.

1984 • 68 citations

Dopamine receptor binding on intact cells. Absence of a high-affinity agonist-receptor binding state.

1983 • 62 citations

Quantitative autoradiography of [3H]sulpiride binding sites in rat brain

1984 • 46 citations

Quantitative determination of dopamine receptor subtypes not linked to activation of adenylate cyclase in rat striatum.

1982 • 39 citations

Thermodynamic differences between agonist and antagonist interactions with binding sites for [3H]spiroperidol in rat striatum.

1983 • 35 citations

High-and Low-Affinity States of Striatal D2Receptors Are Not Affected by 6-Hydroxydopamine or Chronic Haloperidol Treatment

1984 • 35 citations

A densitometer for quantitative autoradiography

1983 • 31 citations

CNS Dopamine Receptors

1983 • 26 citations

Distinctions between ligand-binding sites for [3H]dopamine and D2 dopaminergic receptors characterized with [3H]spiroperidol.

1984 • 20 citations