Lipoxin A4 inhibits acute edema in mice: Implications for the anti-edematogenic mechanism induced by aspirin

Ethical guidelines for investigations of experimental pain in conscious animals

1983 • 7,639 citations

Points of control in inflammation

2002 • 2,599 citations

Lipid mediator class switching during acute inflammation: signals in resolution

2001 • 1,355 citations

Anti-inflammatory lipid mediators and insights into the resolution of inflammation

2002 • 831 citations

Inflammatory Resolution: new opportunities for drug discovery

2004 • 767 citations

Aspirin triggers previously undescribed bioactive eicosanoids by human endothelial cell-leukocyte interactions.

1995 • 694 citations

Cutting Edge: Lipoxins Rapidly Stimulate Nonphlogistic Phagocytosis of Apoptotic Neutrophils by Monocyte-Derived Macrophages

2000 • 620 citations

Formyl-peptide receptors revisited

2002 • 604 citations

Nitric oxide modulates microvascular permeability

1992 • 564 citations

Lipoxins and aspirin-triggered 15-epi-lipoxins are the first lipid mediators of endogenous anti-inflammation and resolution

2005 • 440 citations

Edema and cell infiltration in the phorbol ester-treated mouse ear are temporally separate and can be differentially modulated by pharmacologic agents

1989 • 437 citations

Identification of a human cDNA encoding a functional high affinity lipoxin A4 receptor.

1994 • 431 citations

Aspirin-triggered 15-Epi-Lipoxin A4 (LXA4) and LXA4 Stable Analogues Are Potent Inhibitors of Acute Inflammation: Evidence for Anti-inflammatory Receptors

1997 • 427 citations

Mechanisms of the inflammatory response

2004 • 363 citations

Multi-pronged inhibition of airway hyper-responsiveness and inflammation by lipoxin A4

2002 • 356 citations

Design of Lipoxin A4 Stable Analogs That Block Transmigration and Adhesion of Human Neutrophils

1995 • 326 citations

The role of histamine in allergic diseases

1990 • 321 citations

Lipoxin A4 and B4 are potent stimuli for human monocyte migration and adhesion: selective inactivation by dehydrogenation and reduction.

1996 • 288 citations

International Union of Pharmacology XXXVII. Nomenclature for Leukotriene and Lipoxin Receptors

2003 • 281 citations

Lipoxins, Aspirin-Triggered Epi-Lipoxins, Lipoxin Stable Analogues, and the Resolution of Inflammation

2002 • 280 citations

Trihydroxytetraenes: A novel series of compounds formed from arachidonic acid in human leukocytes

1984 • 252 citations

Increase in vascular permeability induced by leukotriene b4 and the role of polymorphonuclear leukocytes

1982 • 238 citations

Neutrophil-mediated changes in vascular permeability are inhibited by topical application of aspirin-triggered 15-epi-lipoxin A4 and novel lipoxin B4 stable analogues.

1998 • 231 citations

15-epi-lipoxin A4–mediated Induction of Nitric Oxide Explains How Aspirin Inhibits Acute Inflammation

2004 • 230 citations

Lipoxin A4 and B4 inhibit leukotriene-stimulated interactions of human neutrophils and endothelial cells.

1996 • 225 citations

Lipoxin A4 and Lipoxin B4 Inhibit Chemotactic Responses of Human Neutrophils Stimulated by Leukotriene B4 and N-Formyl-<scp>l</scp>-Methionyl-<scp>l</scp>-Leucyl-<scp>l</scp>-Phenylalanine

1989 • 220 citations

Evaluation of the dye-protein tracers in pathophysiology of the blood-brain barrier

1981 • 219 citations

Leukocyte antiadhesive actions of annexin 1: ALXR- and FPR-related anti-inflammatory mechanisms

2003 • 205 citations

Lipoxin (LX)A4 and Aspirin-triggered 15-epi-LXA4 Inhibit Tumor Necrosis Factor 1α–initiated Neutrophil Responses and Trafficking: Regulators of a Cytokine–Chemokine Axis

1999 • 198 citations

Oxidoreductases in Lipoxin A4 Metabolic Inactivation

2000 • 179 citations

A novel role for phospholipase A₂isoforms in the checkpoint control of acute inflammation

2004 • 173 citations

Selectivity of Recombinant Human Leukotriene D4, Leukotriene B4, and Lipoxin A4 Receptors with Aspirin-Triggered 15-epi-LXA4 and Regulation of Vascular and Inflammatory Responses

2001 • 167 citations

Mouse paw edema. A new model for inflammation?

1987 • 164 citations

Lipoxins: revelations on resolution

2001 • 145 citations

Cyclooxygenase-2-Derived Prostaglandin E2 and Lipoxin A4 Accelerate Resolution of Allergic Edema inAngiostrongylus costaricensis-Infected Rats: Relationship with Concurrent Eosinophilia

2000 • 129 citations

Cutting Edge: Lipoxin (LX) A4 and Aspirin-Triggered 15-Epi-LXA4 Block Allergen-Induced Eosinophil Trafficking

2000 • 120 citations

Involvement of B₁ and B₂ receptors in bradykinin‐induced rat paw oedema

1995 • 119 citations

A new method for measuring variations of rat paw volume

1979 • 109 citations

An Aspirin-Triggered Lipoxin A4 Stable Analog Displays a Unique Topical Anti-Inflammatory Profile

2002 • 100 citations

Intrinsic prostacyclin contributes to exudation induced by bradykinin or carrageenin: A study on the paw edema induced in IP-Receptor-deficient mice

2000 • 94 citations

Inflammatory effects of prostacyclin (PGI2) and 6-oxo-PGF1α in the rat paw

1978 • 93 citations

Anti-Inflammatory Actions of Lipoxin A4 Stable Analogs Are Demonstrable in Human Whole Blood: Modulation of Leukocyte Adhesion Molecules and Inhibition of Neutrophil-Endothelial Interactions

1999 • 91 citations

Mechanisms in anti-inflammation and resolution: the role of lipoxins and aspirin-triggered lipoxins

2001 • 91 citations

Lipoxins stimulate prostacyclin generation by human endothelial cells

1989 • 89 citations

Human C5a des Arg increases vascular permeability.

1981 • 89 citations

Inhibition of nitric oxide synthesis increases venular permeability and alters endothelial actin cytoskeleton

1998 • 87 citations

Induction of functional lipoxin A4 receptors in HL-60 cells

1993 • 79 citations

Differential inhibition by two hetrazepine PAF antagonists of acute inflammation in the mouse

1990 • 62 citations

Aspirin-Triggered, Cyclooxygenase-2–Dependent Lipoxin Synthesis Modulates Vascular Tone

2004 • 51 citations

Lipoxins A4 and B4: comparison of icosanoids having bronchoconstrictor and vasodilator actions but lacking platelet aggregatory activity.

1988 • 49 citations

PGI2: A potential mediator of inflammation

1978 • 46 citations

A twist in anti-inflammation: Annexin 1 acts via the lipoxin A4 receptor

2005 • 36 citations

Lipoxin A4 inhibits cholinergic neurotransmission through nitric oxide generation in the rabbit trachea

1995 • 33 citations

Effects of various cyclooxygenase and lipoxygenase metabolites on guinea-pig cerebral arteries

1992 • 21 citations

Protein kinase C‐regulated production of prostacyclin by rat endothelium is increased in the presence of lipoxin A4

1990 • 20 citations

Mesenteric vascular responses to i.v. administration of lipoxin A₄ and lipoxin B₄ in the conscious rat

1988 • 18 citations

Lipoxins A4 and B4 dilate cerebral arterioles of newborn pigs

1989 • 18 citations

Nitric oxide-induced inhibition of mouse paw edema: involvement of soluble guanylate cyclase and potassium channels

2002 • 17 citations

Role of lipoxins A4 and B4 in the generation of arachidonic acid metabolites by rat mast cells and their effect on [3H]serotonin release

1992 • 14 citations