Critical Role of Tyrosine 277 in the Ligand-Binding and Transactivating Properties of Retinoic Acid Receptor α

A decade of molecular biology of retinoic acid receptors

1996 • 2,893 citations

The retinoids; Biology, chemistry, and medicine

1994 • 400 citations

Multiple isoforms of the mouse retinoic acid receptor alpha are generated by alternative splicing and differential induction by retinoic acid.

1991 • 395 citations

Differentially expressed isoforms of the mouse retinoic acid receptor beta generated by usage of two promoters and alternative splicing.

1991 • 390 citations

Activation function 2 (AF-2) of retinoic acid receptor and 9-cis retinoic acid receptor: presence of a conserved autonomous constitutive activating domain and influence of the nature of the response element on AF-2 activity.

1994 • 354 citations

Alteration of a single amino acid residue in retinoic acid receptor causes dominant-negative phenotype.

1994 • 46 citations

Serine 232 and Methionine 272 Define the Ligand Binding Pocket in Retinoic Acid Receptor Subtypes

1998 • 41 citations

In vitro binding of retinoids to the nuclear retinoic acid receptor α

1990 • 35 citations

Arg269 and Lys220 of retinoic acid receptor-beta are important for the binding of retinoic acid.

1994 • 28 citations

Alteration in the Retinoid Specificity of Retinoic Acid Receptor-β by Site-directed Mutagenesis of Arg269 and Lys220

1995 • 26 citations

Differential Role of Homologous Positively Charged Amino Acid Residues for Ligand Binding in Retinoic Acid Receptor α Compared with Retinoic Acid Receptor β

1997 • 19 citations

Identification of Sulfhydryl-modified Cysteine Residues in the Ligand Binding Pocket of Retinoic Acid Receptor β

1997 • 18 citations

Identification of Amino Acids Critical for the DNA Binding and Dimerization Properties of the Human Retinoic Acid Receptor α

1996 • 18 citations