Role of opioid neuropeptides in immunoregulation

Noradrenergic and peptidergic innervation of lymphoid tissue

1985 • 996 citations

A molecular basis for bidirectional communication between the immune and neuroendocrine systems.

1989 • 842 citations

Opioid Peptides Mediate the Suppressive Effect of Stress on Natural Killer Cell Cytotoxicity

1984 • 611 citations

Suggestive Evidence for Receptors for Morphine and Methionine-Enkephalin on Normal Human Blood T Lymphocytes

1979 • 574 citations

Enhancement of natural cytotoxicity by beta-endorphin.

1983 • 457 citations

Opioid Peptides and Opioid Receptors in Cells of the Immune System

1988 • 436 citations

Specific Nonopiate Receptors for β-Endorphin

1979 • 412 citations

Regulation of the in vitro antibody response by neuroendocrine hormones

1982 • 405 citations

beta-Endorphin enhances lymphocyte proliferative responses.

1982 • 393 citations

Corticotropin releasing factor induction of leukocyte-derived immunoreactive ACTH and endorphins

1986 • 361 citations

Human lymphocyte production of corticotropin and endorphin-like substances: association with leukocyte interferon.

1981 • 358 citations

Beta-endorphin and met-enkephalin stimulate human peripheral blood mononuclear cell chemotaxis.

1984 • 292 citations

Activation of Mouse T-Helper Cells Induces Abundant Preproenkephalin mRNA Synthesis

1986 • 269 citations

B-endorphin modulates human immune activity via non-opiate receptor mechanisms

1982 • 234 citations

Stereoselective muscarinic acetylcholine and opiate receptors in human phagocytic leukocytes

1980 • 223 citations

Pro-opiomelanocortin messenger ribonucleic acid and posttranslational processing of beta endorphin in spleen macrophages.

1986 • 221 citations

beta-Endorphin augments the cytolytic activity and interferon production of natural killer cells.

1986 • 213 citations

Opsonizing properties of an isolated hemolymph agglutinin and demonstration of lectin-like recognition molecules at the surface of hemocytes fromMytilus edulis

1983 • 204 citations

Induction of human cutaneous mast cell degranulation by opiates and endogenous opioid peptides: Evidence for opiate and nonopiate receptor participation

1984 • 201 citations

Opiate receptors on lymphocytes and platelets in man

1983 • 190 citations

Endorphins stimulate normal human peripheral blood lymphocyte natural killer activity

1984 • 189 citations

Stress, opioid peptides, the immune system, and cancer

1985 • 188 citations

OPIOID PEPTIDES RAPIDLY STIMULATE SUPEROXIDE PRODUCTION BY HUMAN POLYMORPHONUCLEAR LEUKOCYTES AND MACROPHAGES

1985 • 176 citations

Enkephalins as immunomodulators

1983 • 172 citations

Immunoreactive beta-endorphin in a subpopulation of mouse spleen macrophages.

1984 • 172 citations

Evidence for the involvement of opioid neuropeptides in the adherence and migration of immunocompetent invertebrate hemocytes.

1989 • 160 citations

Stimulatory effects of opioid neuropeptides on locomotory activity and conformational changes in invertebrate and human immunocytes: evidence for a subtype of delta receptor.

1989 • 152 citations

Neuroimmunomodulation with enkephalins: Enhancement of human natural killer (NK) cell activity in vitro

1984 • 136 citations

Isolation and identification of enkephalins in pedal ganglia of Mytilus edulis (Mollusca).

1984 • 116 citations

Effect of alpha-endorphin on the antigen-induced primary antibody response of human blood B cells in vitro.

1986 • 100 citations

Suppression of T lymphocyte chemotactic factor production by the opioid peptides beta-endorphin and met-enkephalin.

1985 • 97 citations

Effects of footshock stress and morphine on natural killer lymphocytes in rats: studies of tolerance and cross-tolerance

1986 • 95 citations

Evidence for a δ-class opioid receptor on cells of the immune system

1988 • 95 citations

Comparative aspects of opioid-dopamine interaction

1982 • 90 citations

Potentiation of histamine-induced itch and flare responses in human skin by the enkephalin analogue FK 33-824, ?-endorphin and morphine

1982 • 83 citations

Comparative neurobiology of opioids in invertebrates with special attention to senescent alterations

1987 • 80 citations

Met-enkephalin induced alterations of macrophage functions

1984 • 75 citations

Involvement of agglutinins (lectins) in invertebrate defense reactions: The immuno-biological importance of carbohydrate-specific binding molecules

1983 • 75 citations

Bidirectional effect of met-enkephalin on macrophage effector functions

1986 • 74 citations

Enkephalins—Enhancement of active T-cell rosettes from lymphoma patients

1983 • 69 citations

Human neutrophil migration is enhanced by beta-endorphin

1984 • 68 citations

Enkephalins—Enhancement of active T-cell rosettes from normal volunteers

1984 • 57 citations

Neutrophil Chemotaxis During and After General Anesthesia and Operation

1976 • 56 citations

Neurobiology of Mytilus edulis

1991 • 56 citations

The effect of β-endorphin on natural cytotoxicity and antibody dependent cellular cytotoxicity

1984 • 54 citations

Β-Endorphin Modulates Immune Functions

1984 • 53 citations

Leu-enkephalin binding to cultured human T lymphocytes

1984 • 46 citations

Migration of human helper/inducer T cells in response to supernatants from Con A-stimulated suppressor/cytotoxic T cells.

1983 • 42 citations

Proenkephalin a-like mRNA in human leukemia leukocytes and CNS-tissues

1986 • 40 citations

Morphine inhibits the carrageenan-induced oedema and the chemoluminescence of leucocytes stimulated by zymosan

1985 • 37 citations

Cell shape of polymorphonuclear leukocytes is influenced by opioids

1985 • 37 citations

Stereospecific opiate binding in living human polymorphonuclear leucocytes

1985 • 36 citations

Enkephalins and endorphins: Activation molecules for the immune system and natural killer activity?

1985 • 34 citations

Presence of met-enkephalin-Arg6-Phe7 in molluscan neural tissues

1984 • 34 citations

Evidence for an inhibitory role of β-endorphin and other opioids on human total T rosette formation

1984 • 34 citations

Enkephalins Modulate in Vivo Immune Reactions Through Delta‐ and Mu‐Opioid Receptorsa

1988 • 33 citations

Influence of morphine and naloxone on human peripheral blood T-lymphocytes

1983 • 32 citations

Leu-enkephalin binding to cultured human T lymphocytes

1984 • 31 citations

High affinity dopamine binding to mouse thymocytes and Mytilus edulis (Bivalvia) hemocytes

1989 • 29 citations

Opioid Peptides in Periphery

1983 • 28 citations

Acute injections of opiate peptides into the rat cerebral ventricle: A macrophage-like cellular response

1983 • 28 citations

The evolvement of signal systems: Conformational matching a determining force stabilizing families of signal molecules

1988 • 27 citations

Opiate receptor mediated internalization of I-?-endorphin in human polymorphonuclear leucocytes

1986 • 25 citations

The Influence of Endogenous Opioid Peptides on Venous Granulocytes

1986 • 19 citations

Opioid Receptors on Murine Splenocytes

1988 • 18 citations

?-Endorphin-like immunoreactivity in plasma cells of the canine colonic mucosa

1980 • 18 citations

Immunoregulation by opioid peptides: I. Absence of classical opioid receptor on human mononuclear cells.

1985 • 15 citations

Neuropeptides are Chemoattractants for Human Monocytes and Tumor Cells: A Basis for Mind-Body Communication

1986 • 14 citations

Interactions of morphine with PGE1, isoproterenol, dopamine and aminophylline in rat mast cells; their effect on IgE-mediated14C-serotonin release

1983 • 13 citations

The effects of opiates on calcium accumulation on rat peritoneal mast cells

1983 • 8 citations

Mediators and Modulators of Human Lymphocyte Chemotaxis

1983 • 8 citations

Interaction of Endogenous Opioids and Developing T Lymphocytes

1988 • 4 citations

Suppression of Anaphylactic Shock by Enkephalinsa

1988 • 4 citations