Impaired Mammary Gland Development in Cyl-1−/− Mice during Pregnancy and Lactation Is Epithelial Cell Autonomous

Cancer Cell Cycles

1996 • 5,379 citations

The retinoblastoma protein and cell cycle control

1995 • 4,873 citations

Inhibitors of mammalian G1 cyclin-dependent kinases.

1995 • 3,258 citations

Mice lacking progesterone receptor exhibit pleiotropic reproductive abnormalities.

1995 • 1,834 citations

Stat5a and Stat5b Proteins Have Essential and Nonessential, or Redundant, Roles in Cytokine Responses

1998 • 1,316 citations

Stat5a is mandatory for adult mammary gland development and lactogenesis.

1997 • 1,106 citations

Overexpression of mouse D-type cyclins accelerates G1 phase in rodent fibroblasts.

1993 • 1,057 citations

Cyclin D1 provides a link between development and oncogenesis in the retina and breast

1995 • 1,017 citations

Development of mammary tumors from hyperplastic alveolar nodules transplanted into gland-free mammary fat pads of female C3H mice.

1959 • 985 citations

Null mutation of the prolactin receptor gene produces multiple reproductive defects in the mouse.

1997 • 797 citations

Genetic Alterations of Cyclins, Cyclin-Dependent Kinases, and Cdk Inhibitors in Human Cancer

1996 • 751 citations

CDK-Independent Activation of Estrogen Receptor by Cyclin D1

1997 • 698 citations

Mice lacking cyclin D1 are small and show defects in eye and mammary gland development.

1995 • 681 citations

Amplification and overexpression of cyclin D1 in breast cancer detected by immunohistochemical staining.

1994 • 673 citations

Prolactin induces phosphorylation of Tyr694 of Stat5 (MGF), a prerequisite for DNA binding and induction of transcription.

1994 • 599 citations

Cloning and expression of Stat5 and an additional homologue (Stat5b) involved in prolactin signal transduction in mouse mammary tissue.

1995 • 556 citations

Cyclin D1 protein expression and function in human breast cancer

1994 • 515 citations

Different Roles for Cyclins D1 and E in Regulation of the G₁-to-S Transition

1995 • 469 citations

Cyclin D1 Stimulation of Estrogen Receptor Transcriptional Activity Independent of cdk4†

1997 • 386 citations

Cyclin D1 induction in breast cancer cells shortens G1 and is sufficient for cells arrested in G1 to complete the cell cycle.

1994 • 377 citations

Estrogen receptor gene disruption: molecular characterization and experimental and clinical phenotypes.

1996 • 371 citations

17beta-Estradiol induces cyclin D1 gene transcription, p36D1-p34cdk4 complex activation and p105Rb phosphorylation during mitogenic stimulation of G(1)-arrested human breast cancer cells.

1996 • 344 citations

Convergence of Mitogenic Signalling Cascades from Diverse Classes of Receptors at the Cyclin D–Cyclin-Dependent Kinase–pRb-Controlled G₁ Checkpoint

1996 • 331 citations

Mammary epithelial cells undergo secretory differentiation in cycling virgins but require pregnancy for the establishment of terminal differentiation

1995 • 285 citations

The C/EBPβ transcription factor regulates epithelial cell proliferation and differentiation in the mammary gland

1998 • 260 citations

Prolactin synthesis and secretion by human breast cancer cells.

1995 • 254 citations

C/EBPβ, but not C/EBPα, is essential for ductal morphogenesis, lobuloalveolar proliferation, and functional differentiation in the mouse mammary gland

1998 • 254 citations

Activation of Stat5a and Stat5b by tyrosine phosphorylation is tightly linked to mammary gland differentiation.

1996 • 228 citations

Elucidation of a role for stromal steroid hormone receptors in mammary gland growth and development using tissue recombinants.

1997 • 216 citations

Transgenic mice carrying an imbalance in the native ratio of A to B forms of progesterone receptor exhibit developmental abnormalities in mammary glands

1998 • 203 citations

Direct action of 17 beta-estradiol on mouse mammary ducts analyzed by sustained release implants and steroid autoradiography.

1987 • 196 citations

Nuclear Factor I and Mammary Gland Factor (STAT5) Play a Critical Role in Regulating Rat Whey Acidic Protein Gene Expression in Transgenic Mice

1995 • 163 citations

Structure of the rat prolactin gene.

1980 • 153 citations

Relative Distribution of Estrogen and Progesterone Receptors among the Epithelial, Adipose, and Connective Tissue Components of the Normal Mammary Gland*

1981 • 102 citations

Genes, oncogenes, and hormones : advances in cellular and molecular biology of breast cancer

1991 • 76 citations

A specific role for cyclin D1 in mammary gland development.

1997 • 62 citations

Hyperplasia of mouse mammary epithelium induced by expression of the Wnt-1 (int-1) oncogene in reconstituted mammary gland.

1992 • 58 citations

Acquisition of estrogen-dependent progesterone receptors by normal mouse mammary gland. Ontogeny of mammary progesterone receptors

1988 • 38 citations

Genetic manipulation of mammary epithelium by transplantation

1996 • 37 citations

Intermediate filament protein expression in normal and malignant human mammary epithelial cells

1991 • 19 citations

Comparison of isotopic and non-isotopic labelling for in situ hybridisation of various mRNA targets with cRNA probes.

1998 • 19 citations

Genomic organization of the mouse cyclin D1 gene (Cyl-1)

1995 • 14 citations

The Mammary Gland

1985 • 6 citations