LIF receptor signaling limits immune-mediated demyelination by enhancing oligodendrocyte survival

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STATs in oncogenesis

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Placebo-controlled multicentre randomised trial of interferon β-1b in treatment of secondary progressive multiple sclerosis

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Multiple extracellular signals are required for long-term oligodendrocyte survival

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Targeted disruption of the low-affinity leukemia inhibitory factor receptor gene causes placental, skeletal, neural and metabolic defects and results in perinatal death

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Differential Production of IL-12, IFN-α, and IFN-γ by Mouse Dendritic Cell Subsets

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A quantitative analysis of oligodendrocytes in multiple sclerosis lesions

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Does oligodendrocyte survival depend on axons?

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Ciliary neurotrophic factor and leukemia inhibitory factor promote the generation, maturation and survival of oligodendrocytes in vitro

1994 • 285 citations

Interferon-gamma-induced oligodendrocyte cell death: implications for the pathogenesis of multiple sclerosis.

1995 • 283 citations

Role of MAP kinase in neurons

1998 • 250 citations

Interferon-γ-Induced Oligodendrocyte Cell Death: Implications for the Pathogenesis of Multiple Sclerosis

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Constitutively activated Stat3 protects fibroblasts from serum withdrawal and UV-induced apoptosis and antagonizes the proapoptotic effects of activated Stat1

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The tripartite CNTF receptor complex: Activation and signaling involves components shared with other cytokines

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Defective Gp130-Mediated Signal Transducer and Activator of Transcription (Stat) Signaling Results in Degenerative Joint Disease, Gastrointestinal Ulceration, and Failure of Uterine Implantation

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McAlpine's Multiple Sclerosis

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Signals transducers and activators of transcription (STAT)-induced STAT inhibitor-1 (SSI-1)/suppressor of cytokine signaling-1 (SOCS-1) suppresses tumor necrosis factor α-induced cell death in fibroblasts

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Treatment of Experimental Autoimmune Encephalomyelitis with Genetically Modified Memory T Cells

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Activation of NF-κB and c-jun Transcription Factors in Multiple Sclerosis Lesions

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Cytokine-Induced Nuclear Factor Kappa B Activation Promotes the Survival of Developing Neurons

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Myelin basic protein gene contains separate enhancers for oligodendrocyte and Schwann cell expression.

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Leukemia Inhibitory Factor Is Expressed in Astrocytes Following Cortical Brain Injury

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Analysis of neuronal and glial phenotypes in brains of mice deficient in leukemia inhibitory factor

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Analysis of neuronal and glial phenotypes in brains of mice deficient in leukemia inhibitory factor

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Suppressor of Cytokine Signaling-1 Attenuates the Duration of Interferon γ Signal Transduction in Vitro and in Vivo

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Cytokines that Signal Through the Leukemia Inhibitory Factor Receptor‐β Complex in the Nervous System

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Targeted expression of baculovirus p35 caspase inhibitor in oligodendrocytes protects mice against autoimmune-mediated demyelination

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Association of a Null Mutation in the CNTF Gene With Early Onset of Multiple Sclerosis

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Neurotrophic Molecules: Strategies for Designing Effective Therapeutic Molecules in Neurodegeneration

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Ciliary neurotrophic factor selectively protects human oligodendrocytes from tumor necrosis factor-mediated injury

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Differentiation of oligodendroglial progenitors derived from cortical multipotent cells requires extrinsic signals including activation of gp130/LIFbeta receptors.

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Oligodendroblasts Distinguished from O-2A Glial Progenitors by Surface Phenotype (O4+GalC-) and Response to Cytokines Using Signal Transducer LIFRβ

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Regulation of leukemia inhibitory factor synthesis in cultured human astrocytes.

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Differentiation of Oligodendroglial Progenitors Derived from Cortical Multipotent Cells Requires Extrinsic Signals Including Activation of gp130/LIFβ Receptors

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Quantitative assessment of blood-brain barrier permeability in multiple sclerosis using 68-Ga-EDTA and positron emission tomography.

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Myelin proteolipid protein: minimum sequence requirements for active induction of autoimmune encephalomyelitis in SWR/J and SJL/J mice

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The adoptive transfer of chronic relapsing experimental allergic encephalomyelitis with lymph node cells sensitized to myelin proteolipid protein

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Treatment of experimental autoimmune encephalomyelitis with antisense oligonucleotides against the low affinity neurotrophin receptor

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Antigen-driven regulation of experimental autoimmune encephalomyelitis

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