Presence of Platelet-derived Growth Factor in Normal and Fibrotic Lung Is Specifically Associated with Interstitial Macrophages, While Both Interstitial Macrophages and Alveolar Epithelial Cells Express the c-sis Proto-oncogene

Efficientin vitrosynthesis of biologically active RNA and RNA hybridization probes from plasmids containing a bacteriophage SP6 promoter

1984 • 6,459 citations

The biology of platelet-derived growth factor

1986 • 2,036 citations

Detection of mRNAs in sea urchin embryos by in situ hybridization using asymmetric RNA probes

1984 • 1,638 citations

Expression and secretion of type beta transforming growth factor by activated human macrophages.

1987 • 981 citations

Growth factors: Mechanism of action and relation to oncogenes

1984 • 885 citations

cDNA sequence and chromosomal localization of human platelet-derived growth factor A-chain and its expression in tumour cell lines

1986 • 786 citations

A significant part of macrophage-derived growth factor consists of at least two forms of PDGF

1985 • 719 citations

Idiopathic Pulmonary Fibrosis

1976 • 706 citations

Fibroblast growth enhancing activity of tumor necrosis factor and its relationship to other polypeptide growth factors.

1986 • 674 citations

Cryptogenic fibrosing alveolitis: clinical features and their influence on survival

1980 • 529 citations

Cultured endothelial cells produce a platelet-derived growth factor-like protein

1983 • 507 citations

Interstitial Lung Diseases of Unknown Cause

1984 • 472 citations

An Immunohistochemical Study of Architectural Remodeling and Connective Tissue Synthesis in Pulmonary Fibrosis

1989 • 469 citations

Exaggerated Spontaneous Release of Platelet-Derived Growth Factor by Alveolar Macrophages from Patients with Idiopathic Pulmonary Fibrosis

1987 • 420 citations

Production of platelet-derived growth factor-like molecules by cultured arterial smooth muscle cells accompanies proliferation after arterial injury.

1986 • 393 citations

Activated human monocytes express the c-sis proto-oncogene and release a mediator showing PDGF-like activity

1986 • 380 citations

Platelet-derived growth factor in idiopathic pulmonary fibrosis.

1990 • 376 citations

Production of fibronectin by the human alveolar macrophage: mechanism for the recruitment of fibroblasts to sites of tissue injury in interstitial lung diseases.

1981 • 344 citations

Polypeptide Growth Factors: Roles In Normal And Abnormal Cell Growth

1987 • 339 citations

Alveolar macrophages release an insulin-like growth factor I-type molecule.

1988 • 255 citations

Expression of the sis gene by endothelial cells in culture and in vivo.

1984 • 221 citations

Mechanisms of pulmonary fibrosis. Spontaneous release of the alveolar macrophage-derived growth factor in the interstitial lung disorders.

1983 • 217 citations

Arterial smooth muscle cells express platelet-derived growth factor (PDGF) A chain mRNA, secrete a PDGF-like mitogen, and bind exogenous PDGF in a phenotype- and growth state-dependent manner

1988 • 205 citations

Upregulation of platelet-derived growth factor-A and -B gene expression in alveolar macrophages of individuals with idiopathic pulmonary fibrosis.

1990 • 179 citations

Platelet-derived growth factor. Structure, function, and roles in normal and transformed cells.

1984 • 178 citations

Comparison of production of transforming growth factor-beta and platelet-derived growth factor by normal human mesothelial cells and mesothelioma cell lines.

1987 • 176 citations

Spontaneous expression of the c-sis gene and release of a platelet-derived growth factorlike molecule by human alveolar macrophages.

1986 • 144 citations

Expression of c-sis (PDGF B-chain) and PDGF A-chain genes in ten human malignant mesothelioma cell lines derived from primary and metastatic tumors.

1988 • 100 citations

Differential Expression of the Tumor Necrosis Factor/Cachectin Gene by Blood and Lung Mononuclear Phagocytes

1988 • 92 citations

Differential expression of platelet‐derived growth factor and transforming growth factor genes in small‐ and non‐small‐cell human lung carcinoma lines

1988 • 78 citations

Functional identification of regulatory elements within the promoter region of platelet-derived growth factor 2.

1989 • 67 citations

Modulation of fibronectin gene expression in human mononuclear phagocytes.

1987 • 57 citations

Expression of platelet-derived growth factor (PDGF)-related transcripts and synthesis of biologically active PDGF-like proteins by human malignant epithelial cell lines.

1988 • 52 citations

The distribution of phenotypically distinct macrophage subsets in the lungs of patients with cryptogenic fibrosing alveolitis.

1989 • 22 citations