Decreased cerebrospinal fluid neuropeptide Y (NPY) in patients with treatment refractory unipolar major depression: preliminary evidence for association with preproNPY gene polymorphism

A Diagnostic Interview

1978 • 5,735 citations

Neuropeptide Y—a novel brain peptide with structural similarities to peptide YY and pancreatic polypeptide

1982 • 2,244 citations

Allostasis and Allostatic Load Implications for Neuropsychopharmacology

2000 • 1,699 citations

THE CEREBROSPINAL FLUID

1938 • 896 citations

Modulation of Anxiety and Neuropeptide Y-Y1 Receptors by Antisense Oligodeoxynucleotides

1993 • 528 citations

Hamilton Depression Rating Scale

1981 • 421 citations

Centrally administered neuropeptide Y (NPY) produces anxiolytic-like effects in animal anxiety models

1989 • 378 citations

Anxiolytic-Like Action of Neuropeptide Y: Mediation by Y1 Receptors in Amygdala, and Dissociation from Food Intake Effects

1993 • 363 citations

The neurocircuitry and receptor subtypes mediating anxiolytic-like effects of neuropeptide Y

2002 • 342 citations

Corticotropin-releasing factor and neuropeptide y: role in emotional integration

1994 • 320 citations

Behavioral insensitivity to restraint stress, absent fear suppression of behavior and impaired spatial learning in transgenic rats with hippocampal neuropeptide Y overexpression

2000 • 306 citations

CSF monoamine metabolites in melancholia

1984 • 286 citations

Dynamic allele-specific hybridization

1999 • 284 citations

Neurotransmitters and Suicidal Behavior

1997 • 276 citations

Neuropeptide Y and peptide YY as possible cerebrospinal fluid markers for major depression and schizophrenia, respectively

1988 • 256 citations

Amygdalar neuropeptide Y Y1 receptors mediate the anxiolytic-like actions of neuropeptide Y in the social interaction test

1999 • 239 citations

Decreased experimental anxiety and voluntary ethanol consumption in rats following central but not basolateral amygdala lesions

1997 • 229 citations

Association of a leucine(7)-to-proline(7) polymorphism in the signal peptide of neuropeptide Y with high serum cholesterol and LDL cholesterol levels

1998 • 218 citations

Robust and Accurate Single Nucleotide Polymorphism Genotyping by Dynamic Allele-Specific Hybridization (DASH): Design Criteria and Assay Validation

2001 • 194 citations

CSF Somatostatin in Affective Illness

1983 • 190 citations

Behavioral effects of neuropeptide Y receptor agonists in the elevated plus-maze and fear-potentiated startle procedures

1995 • 190 citations

Antisense inhibition of neuropeptide Y (NPY)-Y1 receptor expression blocks the anxiolytic-like action of NPY in amygdala and paradoxically increases feeding

1995 • 182 citations

A Functional Neuropeptide Y Leu7Pro Polymorphism Associated With Alcohol Dependence in a Large Population Sample From the United States

2002 • 173 citations

Behavioral and endocrine adaptation, and up-regulation of NPY expression in rat amygdala following repeated restraint stress

1999 • 158 citations

Reduced Neuropeptide Y Concentrations in Suicide Brain

1992 • 158 citations

Neuropeptide Y (NPY) and depression: From animal studies to the human condition

2002 • 143 citations

Neuropeptide-Y exerts antidepressant-like effects in the forced swim test in rats

2000 • 142 citations

The role of neuropeptide Y in cardiovascular regulation

1991 • 131 citations

Neuropeptide Y promotes sleep and inhibits ACTH and cortisol release in young men

2000 • 128 citations

Effect of a selective neuropeptide Y Y2 receptor antagonist, BIIE0246 on neuropeptide Y release

2000 • 124 citations

Altered intracellular processing and release of neuropeptide Y due to leucine 7 to proline 7 polymorphism in the signal peptide of preproneuropeptide Y in humans

2001 • 119 citations

Brain Neuropeptide Υ (NPY) in Stress and Alcohol Dependence

2002 • 116 citations

Involvement of hippocampal neuropeptide Y in mediating the chronic actions of lithium, electroconvulsive stimulation and citalopram

2000 • 116 citations

Electroconvulsive shocks increase the concentration of neocortical and hippocampal neuropeptide Y (NPY)-like immunoreactivity in the rat

1990 • 108 citations

Alterations in neuropeptide Y levels and Y1 binding sites in the Flinders Sensitive Line rats, a genetic animal model of depression

1999 • 100 citations

Suppressed neuropeptide Y (NPY) mRNA in rat amygdala following restraint stress

1998 • 100 citations

Effect of repeated electroconvulsive treatment on regional concentrations of tachykinins, neurotensin, vasoactive intestinal polypeptide, neuropeptide Y, and galanin in rat brain

1989 • 96 citations

Cerebrospinal fluid neuropeptides in mood disorder and dementia

1992 • 90 citations

Low levels of somatostatin in human CSF mark depressive episodes

1984 • 89 citations

Reduced neuropeptide Y mRNA expression in the prefrontal cortex of subjects with bipolar disorder

1999 • 85 citations

Neuropeptide Y polymorphism and alcohol consumption in middle‐aged men

2000 • 79 citations

Cerebrospinal fluid monoamine metabolites in 114 healthy individuals 18–88 years of age

1993 • 70 citations

Cerebrospinal fluid neuropeptide Y in depression and schizophrenia

1987 • 68 citations

Neuropeptide Y polymorphism and alcohol consumption in middle-aged men

2000 • 67 citations

NPY leu7pro and Alcohol Dependence in Finnish and Swedish Populations

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CSF monoamine metabolites and somatostatin in Alzheimer's disease and major depression

1991 • 56 citations

Cerebrospinal fluid neuropeptides in Alzheimer's disease and vascular dementia

1995 • 43 citations

Neuropeptide Y in Frontal Cortex Is Not Altered in Major Depression

1995 • 37 citations

Cerebrospinal Fluid Immunoreactive Somatostatin Concentrations in Patients with Cushing’s Disease and Major Depression: Relationship to Indices of Corticotropin-Releasing Hormone and Cortisol Secretion

1993 • 29 citations

Neuropeptides and Alzheimer's disease

1995 • 23 citations

Novel Neuropeptide Y Processing in Human Cerebrospinal Fluid From Depressed Patients

1996 • 20 citations

Neuropeptides and Alzheimer's disease

1995 • 13 citations

Age-related increase in neuropeptide Y-like immunoreactivity in cerebrospinal fluid in women.

1994 • 11 citations

Robust and Accurate Single Nucleotide Polymorphism Genotyping by Dynamic Allele Specific Hybridization (DASH)

2001 • 1 citations