Differential regulation of μ‐opiate receptors in heroin‐ and morphine‐dependent rats

PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT

1951 • 319,299 citations

Protein Determination of Large Numbers of Samples

1959 • 1,591 citations

Opiate Receptor Binding of Agonists and Antagonists Affected Differentially by Sodium

1974 • 554 citations

Opiate Agonists and Antagonists Discriminated by Receptor Binding in Brain

1973 • 527 citations

Analogues of β-LPH61–64 posessing selective agonist activity at μ-opiate receptors

1981 • 503 citations

SPECTRUM OF THE μ‐, δ‐ AND κ‐BINDING SITES IN HOMOGENATES OF RAT BRAIN

1982 • 278 citations

Quantitative aspects of precipitated abstinence in morphine-dependent rats.

1973 • 252 citations

The Pharmacokinetics of Heroin in Patients with Chronic Pain

1984 • 242 citations

Evidence from opiate binding studies that heroin acts through its metabolites

1983 • 207 citations

Narcotic Receptor Sites in Morphine-dependent Rats

1974 • 201 citations

Cellular site of opiate dependence

1980 • 201 citations

A comparative study of physiological and subjective effects of heroin and morphine administered intravenously in postaddicts.

1961 • 153 citations

The pharmacologic effects of heroin in relationship to its rate of biotransformation.

1960 • 140 citations

Separation of Morphine Analgesia from Physical Dependence

1984 • 126 citations

Repeated electroconvulsive shock or chronic morphine treatment increases the number of 3HDALA2, DLEU5enkephalin binding sites in rat brain membranes

1982 • 106 citations

Affinity Labels for Opioid Receptors

1985 • 103 citations

Clinical characteristics of addictions

1953 • 96 citations

Morphine tolerance increases μ-noncompetative δ binding sites

1986 • 88 citations

Supersensitivity of brain opiate receptor subtypes after chronic naltrexone treatment

1982 • 87 citations

Opiate Receptor: Multiple Effects of Metal Ions

1982 • 68 citations

Differences in Binding Properties of μ and δ Opioid Receptor Subtypes from Rat Brain: Kinetic Analysis and Effects of Ions and Nucleotides

1985 • 66 citations

Comparison of intravenously administered methadone, morphine and heroin

1986 • 55 citations

Multiple opiate binding sites in the central nervous system of the rabbit. Large predominance of a mu subtype in the cerebellum and characterization of a kappa subtype in the thalamus.

1983 • 55 citations

Differential regulation of the mu-, delta-, and kappa-opiate receptor subtypes by guanyl nucleotides and metal ions

1982 • 50 citations

Absence of Cross-Tolerance to Heroin in Morphine-Tolerant Mice

1980 • 49 citations

Different receptor sites mediate opioid agonism and antagonism

1983 • 43 citations

Receptor-mediated stimulation of brain GTPase by opiates in normal and dependent rats

1984 • 42 citations

High and low affinity opioid binding sites: Relationship to mu and delta sites

1982 • 40 citations

Enkephalin levels in rat brain after various regimens of morphine administration

1979 • 33 citations

Differential effects of heroin on opioid levels in the rat brain

1987 • 20 citations

In vivo binding of naloxone to opioid receptors in morphine-dependent mice

1983 • 14 citations

Hypothalamic ACTH and MSH levels increase in morphine tolerance and decrease after morphine withdrawal

1983 • 11 citations

Mechanism of opioid tolerance and dependence

1984 • 10 citations

Properties of opiate binding in the rat spinal cord

1982 • 6 citations

Tolerance and withdrawal are associated with ligand dependent receptor regulation in vitro and in vivo

1984 • 5 citations

Sodium-induced alterations of opiate effects on the binding of 3H-dihydromorphine to mouse brain homogenates

1978 • 2 citations

Effects of acute administration of and tolerance development to morphine on the striatal calmodulin systems in mice of different ages

1984 • 2 citations