Cytolysin-Mediated Translocation (CMT)

Normal keratinization in a spontaneously immortalized aneuploid human keratinocyte cell line.

1988 • 4,008 citations

Type III Protein Secretion Systems in Bacterial Pathogens of Animals and Plants

1998 • 2,394 citations

Type III Secretion Machines: Bacterial Devices for Protein Delivery into Host Cells

1999 • 1,280 citations

Streptococcal Infections of Skin and Soft Tissues

1996 • 1,000 citations

Caveolae, DIGs, and the dynamics of sphingolipid—cholesterol microdomains

1997 • 783 citations

Type 1 pilus-mediated bacterial invasion of bladder epithelial cells

2000 • 727 citations

The Yersinia Yop virulon: a bacterial system for subverting eukaryotic cells

1997 • 564 citations

Structure of a Cholesterol-Binding, Thiol-Activated Cytolysin and a Model of Its Membrane Form

1997 • 459 citations

Listeriolysin O is essential for virulence of Listeria monocytogenes: direct evidence obtained by gene complementation

1989 • 426 citations

Virulence Mechanisms of Bacterial Pathogens

2016 • 400 citations

How do cytotoxic lymphocytes kill their targets?

1998 • 398 citations

The Mechanism of Membrane Insertion for a Cholesterol-Dependent Cytolysin

1999 • 358 citations

Regulation of calcium signalling in T lymphocytes by the second messenger cyclic ADP-ribose

1999 • 308 citations

Group A streptococci efficiently invade human respiratory epithelial cells.

1994 • 284 citations

A conserved amino acid sequence directing intracellular type III secretion by Salmonella typhimurium

2000 • 278 citations

Streptococcal toxins (streptolysin O, streptolysin S, erythrogenic toxin)

1980 • 266 citations

C5a peptidase alters clearance and trafficking of group A streptococci by infected mice

1996 • 234 citations

A guide to the use of pore-forming toxins for controlled permeabilization of cell membranes

1993 • 232 citations

Insertion of a Yop translocation pore into the macrophage plasma membrane by Yersinia enterocolitica: requirement for translocators YopB and YopD, but not LcrG

1999 • 220 citations

Environmental regulation of virulence in group A streptococci: transcription of the gene encoding M protein is stimulated by carbon dioxide

1992 • 197 citations

Two different but converging messenger pathways to intracellular Ca2+ release: the roles of nicotinic acid adenine dinucleotide phosphate, cyclic ADP-ribose and inositol trisphosphate

2000 • 187 citations

YopB and YopD constitute a novel class of Yersinia Yop proteins

1993 • 179 citations

Yersinia enterocolitica type III secretion-translocation system: channel formation by secreted Yops

1999 • 156 citations

Extracellular Cysteine Protease Produced by Streptococcus pyogenes Participates in the Pathogenesis of Invasive Skin Infection and Dissemination in Mice

1999 • 151 citations

Reduced Virulence of Group A Streptococcal Tn 916 Mutants That Do Not Produce Streptolysin S

1998 • 141 citations

Conversion of an M- group A streptococcus to M+ by transfer of a plasmid containing an M6 gene.

1986 • 141 citations

Thiol-activated cytolysins: structure, function and role in pathogenesis

2000 • 129 citations

Streptolysin O and adherence synergistically modulate proinflammatory responses of keratinocytes to group A streptococci

1998 • 127 citations

Positive transcriptional control of mry regulates virulence in the group A streptococcus

1993 • 117 citations

Invasion of cultured human cells by Streptococcus pyogenes

1995 • 109 citations

Effect of Group A Streptococcal Cysteine Protease on Invasion of Epithelial Cells

1998 • 86 citations

A ring-shaped structure with a crown formed by streptolysin O on the erythrocyte membrane

1993 • 86 citations

Use of Genetically Manipulated Strains of Clostridium perfringens Reveals that Both Alpha-Toxin and Theta-Toxin Are Required for Vascular Leukostasis To Occur in Experimental Gas Gangrene

1999 • 82 citations

Type III machines of pathogenic yersiniae secrete virulence factors into the extracellular milieu

1999 • 81 citations

Type III machines of Gram-negative bacteria: delivering the goods

2000 • 81 citations

An Arcanobacterium ( Actinomyces ) pyogenes Mutant Deficient in Production of the Pore-Forming Cytolysin Pyolysin Has Reduced Virulence

1999 • 71 citations

A STREPTOCOCCAL ENZYME THAT ACTS SPECIFICALLY UPON DIPHOSPHOPYRIDINE NUCLEOTIDE: CHARACTERIZATION OF THE ENZYME AND ITS SEPARATION FROM STREPTOLYSIN O

1957 • 67 citations

Keratinocyte proinflammatory responses to adherent and nonadherent group A streptococci

1997 • 49 citations

Virulence Mechanisms of Bacterial Pathogens

1994 • 48 citations

Spinning tails: homologies among bacterial flagellar systems

1996 • 45 citations

Saponin and Other Haemolysins (Vitamin A, Aliphatic Amines, Polyene Antibiotics) as Adjuvants for SRBC in the Mouse

1980 • 43 citations

NAD⁺-glycohydrolase fromStreptococcus pyogenesshows cyclic ADP-ribose forming activity

1995 • 42 citations

Thiol-activated cytolysins

1996 • 37 citations

Application of a new method for detecting streptococcal nicotinamide adenine dinucleotide glycohydrolase to various M types of Streptoccus pyogenes

1976 • 18 citations

Purification and some properties of streptococcal NAD-glycohydrolase

1996 • 15 citations