Rapid modulation of osteoblast ion channel responses by 1α,25(OH) ₂ -vitamin D ₃ requires the presence of a functional vitamin D nuclear receptor

Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches

1981 • 18,584 citations

Down-Regulation of Na⁺/K⁺ATPase Activity by Human Parvovirus B19 Capsid Protein VP1

2013 • 8,607 citations

The nuclear receptor superfamily: The second decade

1995 • 6,929 citations

Regulation of the Voltage Gated K<sup>+</sup> Channel K<sub>v1.3</sub> by Recombinant Human Klotho Protein

2014 • 5,592 citations

Structure-Function Relationships in the Vitamin D Endocrine System*

1995 • 1,182 citations

Mice lacking the vitamin D receptor exhibit impaired bone formation, uterine hypoplasia and growth retardation after weaning

1997 • 1,149 citations

Nongenotropic, Sex-Nonspecific Signaling through the Estrogen or Androgen Receptors

2001 • 1,123 citations

Targeted ablation of the vitamin D receptor: An animal model of vitamin D-dependent rickets type II with alopecia

1997 • 933 citations

Duodenal calcium absorption in vitamin D receptor–knockout mice: Functional and molecular aspects

2001 • 579 citations

Steroid-hormone rapid actions, membrane receptors and a conformational ensemble model

2004 • 556 citations

Nongenomic Steroid Action: Controversies, Questions, and Answers

2003 • 553 citations

Rescue of the Skeletal Phenotype of Vitamin D Receptor-Ablated Mice in the Setting of Normal Mineral Ion Homeostasis: Formal Histomorphometric and Biomechanical Analyses1

1999 • 499 citations

Impaired insulin secretory capacity in mice lacking a functional vitamin D receptor

2003 • 429 citations

Rapid Actions of Steroid Receptors in Cellular Signaling Pathways

2002 • 362 citations

Inactivating Mutations in the 25-Hydroxyvitamin D₃1α-Hydroxylase Gene in Patients with Pseudovitamin D–Deficiency Rickets

1998 • 360 citations

Identification of a Structural Determinant Necessary for the Localization and Function of Estrogen Receptor α at the Plasma Membrane

2003 • 317 citations

Nuclear-Receptor Ligands and Ligand-Binding Domains

1999 • 314 citations

Identification of a specific binding protein for 1 alpha,25-dihydroxyvitamin D3 in basal-lateral membranes of chick intestinal epithelium and relationship to transcaltachia.

1994 • 310 citations

Capacitance steps and fusion pores of small and large-dense-core vesicles in nerve terminals

2002 • 295 citations

Fast insulin secretion reflects exocytosis of docked granules in mouse pancreatic B-cells

2002 • 283 citations

Deletion of Deoxyribonucleic Acid Binding Domain of the Vitamin D Receptor Abrogates Genomic and Nongenomic Functions of Vitamin D

2002 • 277 citations

ERβ Has Nongenomic Action in Caveolae

2002 • 265 citations

Vitamin D3 Metabolites Modulate Dihydropyridine-sensitive Calcium Currents in Clonal Rat Osteosarcoma Cells

1989 • 241 citations

Identification of a Membrane Receptor for 1,25-Dihydroxyvitamin D3 Which Mediates Rapid Activation of Protein Kinase C

1998 • 218 citations

Demonstration that 1 beta,25-dihydroxyvitamin D3 is an antagonist of the nongenomic but not genomic biological responses and biological profile of the three A-ring diastereomers of 1 alpha,25-dihydroxyvitamin D3.

1993 • 182 citations

Characterization of a vitamin D receptor knockout mouse as a model of colorectal hyperproliferation and DNA damage

2001 • 179 citations

Intracellular signaling pathways: nongenomic actions of estrogens and ligand-independent activation of estrogen receptors

2001 • 178 citations

Calcium regulates exocytosis at the level of single vesicles

2003 • 147 citations

Stimulation of Phosphorylation of Mitogen-Activated Protein Kinase by 1α,25-Dihydroxyvitamin D3 in Promyelocytic NB4 Leukemia Cells: A Structure-Function Study*

1998 • 126 citations

1,25(OH)₂‐vitamin D₃ induces translocation of the vitamin D receptor (VDR) to the plasma membrane in skeletal muscle cells

2002 • 123 citations

An Insulinotropic Effect of Vitamin D Analog with Increasing Intracellular Ca2+ Concentration in Pancreatic β-Cells through Nongenomic Signal Transduction1

1999 • 111 citations

Navigating Steroid Hormone Receptors through the Nuclear Compartment

2002 • 108 citations

Stimulation by 1α,25(OH)2-Vitamin D3 of Whole Cell Chloride Currents in Osteoblastic ROS 17/2.8 Cells

1997 • 100 citations

Growth Hormone Increases Bone Mineral Content in Postmenopausal Osteoporosis: A Randomized Placebo-Controlled Trial

2003 • 94 citations

Localization of Ca2+ Extrusion Sites in Pancreatic Acinar Cells

1996 • 88 citations

Nuclear receptors, coactivators and chromatin: new approaches, new insights

2001 • 77 citations

Estimation of mean exocytic vesicle capacitance in mouse adrenal chromaffin cells

1997 • 75 citations

Evidence for distinct membrane receptors for 1α,25-(OH)2D3 and 24R,25-(OH)2D3 in osteoblasts

2002 • 68 citations

Antagonistic effects of transforming growth factor-beta on vitamin D3 enhancement of osteocalcin and osteopontin transcription: reduced interactions of vitamin D receptor/retinoid X receptor complexes with vitamin E response elements.

1996 • 62 citations

A specific binding protein/receptor for 1α,25-dihydroxyvitamin D3 is present in an intestinal caveolae membrane fraction

2002 • 57 citations

Further analysis of spontaneous membrane potential activity and the hyperpolarizing response to parathyroid hormone in osteoblastlike cells

1987 • 45 citations

Altered Expression of Bone Sialoproteins in Vitamin D–Deficient rBSP2.7Luc Transgenic Mice

1999 • 43 citations

Multiple molecular mechanisms of 1α,25(oh)2-vitamin D3 rapid modulation of three ion channel activities in osteoblasts

2003 • 33 citations

Control of intracellular pH in rat calvarial osteoblasts: Coexistence of both chloride-bicarbonate and sodium-hydrogen exchange

1988 • 20 citations

Potassium currents and effects of vitamin D-3 metabolites and cyclic GMP in rat osteoblastic cells

1993 • 10 citations