Evidence for vesicles that mediate long-chain fatty acid uptake by human microvascular endothelial cells

A SIMPLE METHOD FOR THE ISOLATION AND PURIFICATION OF TOTAL LIPIDES FROM ANIMAL TISSUES

1957 • 63,238 citations

HMEC-1: Establishment of an Immortalized Human Microvascular Endothelial Cell Line

1992 • 1,258 citations

Cloning of a rat adipocyte membrane protein implicated in binding or transport of long-chain fatty acids that is induced during preadipocyte differentiation. Homology with human CD36.

1993 • 982 citations

Filipin-sensitive caveolae-mediated transport in endothelium: reduced transcytosis, scavenger endocytosis, and capillary permeability of select macromolecules.

1994 • 894 citations

Caveolin moves from caveolae to the Golgi apparatus in response to cholesterol oxidation.

1994 • 425 citations

Pneumococcal trafficking across the blood-brain barrier. Molecular analysis of a novel bidirectional pathway.

1998 • 393 citations

Murine SR-BI, a High Density Lipoprotein Receptor That Mediates Selective Lipid Uptake, Is N-Glycosylated and Fatty Acylated and Colocalizes with Plasma Membrane Caveolae

1997 • 375 citations

Unbound free fatty acid levels in human serum.

1995 • 310 citations

The Cellular Fatty Acid Binding Proteins: Aspects of Structure, Regulation, and Function

1988 • 308 citations

Regulation of caveolin and caveolae by cholesterol in MDCK cells

1998 • 307 citations

Acyltransferases and Transacylases Involved in Fatty Acid Remodeling of Phospholipids and Metabolism of Bioactive Lipids in Mammalian Cells

1997 • 293 citations

Analysis of long-chain free fatty acid binding to bovine serum albumin by determination of stepwise equilibrium constants

1971 • 271 citations

Mechanism of long chain fatty acid permeation in the isolated adipocyte.

1981 • 262 citations

Caveolin cycles between plasma membrane caveolae and the Golgi complex by microtubule-dependent and microtubule-independent steps.

1995 • 243 citations

Fatty acid uptake by isolated rat heart myocytes represents a carrier-mediated transport process.

1988 • 214 citations

Hepatocellular uptake of oleate is energy dependent, sodium linked, and inhibited by an antibody to a hepatocyte plasma membrane fatty acid binding protein.

1986 • 210 citations

Identification of Caveolin-1 as a Fatty Acid Binding Protein

1999 • 200 citations

Internalization and subcellular localization of transferrin and transferrin receptors in HeLa cells.

1983 • 172 citations

Peroxisome Proliferator–Activated Receptors: A Critical Link among Fatty Acids, Gene Expression and Carcinogenesis

1999 • 129 citations

NEM inhibits transcytosis, endocytosis, and capillary permeability: implication of caveolae fusion in endothelia

1995 • 127 citations

Isolation and characterization of peroxisomes from the liver of normal untreated rats

1985 • 126 citations

Biochemical and biophysical identification of cystic fibrosis transmembrane conductance regulator chloride channels as components of endocytic clathrin-coated vesicles.

1994 • 116 citations

Uptake of long-chain fatty acids in HepG2 cells involves caveolae

2002 • 108 citations

Clathrin polymerization is not required for bulk-phase endocytosis in rat fetal fibroblasts.

1994 • 102 citations

Uptake of oleate from albumin solutions by rat liver. Failure to detect catalysis of the dissociation of oleate from albumin by an albumin receptor.

1987 • 100 citations

Intracellular Transport of Low Density Lipoprotein Derived Free Cholesterol Begins at Clathrin-Coated Pits and Terminates at Cell Surface Caveolae

1996 • 98 citations

Nitrogen Cavitation for Cell Disruption to Obtain Mitochondria from Cultured Cells

2000 • 90 citations

The expression of scavenger receptor class B, type I (SR-BI) and caveolin-1 in parenchymal and nonparenchymal liver cells

2001 • 67 citations

Depletion of intracellular potassium disrupts coated pits and reversibly inhibits cell polarization during fibroblast spreading.

1993 • 63 citations

Transport of Long-Chain Fatty Acids across the Muscular Endothelium

1998 • 54 citations

Effect of endocytosis inhibitors on alveolar clearance of albumin, immunoglobulin G, and SP-A in rabbits

1994 • 49 citations

Fatty acids binding to albumin increases its uptake and transcytosis by the lung capillary endothelium.

1988 • 48 citations

Association of the fusion protein NSF with clathrin-coated vesicle membranes.

1996 • 45 citations

A method of computing drug distribution in plasma using stepwise association constants: Clofibrate acid as an illustrative example

1976 • 43 citations

Skeletal Muscle Metabolism in Exercise and Diabetes

1998 • 42 citations

Linolenic Acid Transport in Hamster Intestinal Cells Is Carrier-Mediated

1993 • 39 citations

Oleic acid distribution in small intestinal epithelial cells expressing intestinal-fatty acid binding protein

1998 • 34 citations

Identification of high affinity membrane-bound fatty acid-binding proteins using a photoreactive fatty acid

1993 • 33 citations

Zinc transport across an endothelium includes vesicular cotransport with albumin

1996 • 32 citations

Fatty acids are not an important fuel for coronary microvascular endothelial cells

1989 • 31 citations

The effects of inhibitors of vacuolar acidification on the release of Listeria monocytogenes from phagosomes of Caco-2 cells

1996 • 29 citations

Rapid transport of fatty acids from rat liver endothelial to parenchymal cells after uptake of cholesteryl ester-labeled acetylated LDL

1986 • 21 citations

Caveolar Microdomains of the Sarcolemma

1999 • 17 citations

Hepatic transport of a fluorescent stearate derivative: electrochemical driving forces in intact rat liver

1991 • 16 citations

Specific inhibition of endothelial cell proliferation by isolated endothelial plasma membranes

1986 • 15 citations

Use of a Human Microvascular Endothelial Cell Line as a Model System to Evaluate Cholesterol Uptake

1993 • 13 citations