The usefulness of human tumor cell lines in the study of chemosensitivity. A study of malignant melanomas

Quantitation of Differential Sensitivity of Human-Tumor Stem Cells to Anticancer Drugs

1978 • 982 citations

Prospective clinical trial of a human tumor cloning system.

1983 • 340 citations

An in vitro colony assay for human tumours grown in immune-suppressed mice and treated in vivo with cytotoxic agents

1978 • 296 citations

IN-VITRO CLONOGENIC ASSAY FOR PREDICTING RESPONSE OF OVARIAN CANCER TO CHEMOTHERAPY

1980 • 165 citations

The cytotoxic action of carcinolytic agents in tissue culture

1956 • 140 citations

Combination chemotherapy in vitro with adriamycin. Observations of additive, antagonistic, and synergistic effects when used in two-drug combinations on cultured human lymphoma cells.

1976 • 120 citations

Basis for natural variation in sensitivity to 5-fluorouracil in mouse and human cells in culture.

1979 • 104 citations

Levodopa and dopamine analogs as DNA polymerase inhibitors and antitumor agents in human melanoma.

1980 • 89 citations

Combination chemotherapy in vitro with cis-dichlorodiammineplatinum(II).

1976 • 69 citations

Evaluation of a “Nude” Mouse-Human Tumor Panel as a Predictive Secondary Screen for Cancer Chemotherapeutic Agents<xref ref-type="fn" rid="FN2">2</xref>

1979 • 58 citations

Rhodium (II) Butyrate: A Potential Anticancer Drug With Cell Cycle Phase-Specific Effects in HeLa Cells<xref ref-type="fn" rid="FN2">2</xref>

1980 • 56 citations

Do cell lines in vitro reflect the properties of the tumours of origin? A study of lines derived from human melanoma xenografts

1981 • 50 citations

An approach to the problem of heterogeneity of human tumour-cell populations

1979 • 50 citations

A human melanoma cell line established from xenograft in athymic mice

1980 • 50 citations

Human tumour xenografts: a critical appraisal.

1980 • 40 citations

Assessment of tumour growth and of response to chemotherapy of human melanomas in athymic, nude mice.

1980 • 36 citations

In vitro sensitivity of human melanoma xenografts to cytotoxic drugs. Correlation within vivo chemosensitivity

1980 • 33 citations

Rapid Assays for Evaluating the Drug Sensitivity of Tumor Cells2

1977 • 32 citations

Studies on the mechanism of action of DTIC (NSC-45388).

1976 • 24 citations

An inverse relationship between the growth rate of human melanoma xenografts and their response to some cytostatic drugs

1980 • 18 citations

Screening for anti-cancer agents; the relative merits of in vitro and in vivo techniques

1975 • 18 citations

Chemosensitivity of human bladder cancer cells in long-term culture and clinical responses to the selected anticancer drug

1979 • 17 citations

Amygdalin (Laetrile): effect on clonogenic cells from human myeloid leukemia cell lines and normal human marrow.

1980 • 14 citations

Biochemical parameters of growth inhibition of human leukemia cells by antitumor anthracycline agents.

1979 • 10 citations

Utilization of metabolic activation for in vitro screening of potential antineoplastic agents.

1979 • 9 citations