Nongenomic effects of neurosteroids

Steroid Hormone Metabolites Are Barbiturate-Like Modulators of the GABA Receptor

1986 • 2,194 citations

Molecular biology of GABA _A receptors

1990 • 947 citations

Stress-induced elevations of gamma-aminobutyric acid type A receptor-active steroids in the rat brain.

1991 • 943 citations

Excitatory amino acids in the brain - focus on NMDA receptors

1987 • 641 citations

A corticosteroid Receptor in Neuronal Membranes

1991 • 522 citations

Modulation of the GABA receptor complex by a steroid anaesthetic

1984 • 496 citations

Steroid modulation of the chloride ionophore in rat brain: structure-activity requirements, regional dependence and mechanism of action.

1988 • 459 citations

Neurosteroids, via sigma receptors, modulate the [3H]norepinephrine release evoked by N-methyl-D-aspartate in the rat hippocampus.

1995 • 426 citations

Neurosteroid biosynthesis: genes for adrenal steroidogenic enzymes are expressed in the brain

1993 • 402 citations

EPILEPTIC SEIZURES IN WOMEN RELATED to PLASMA ESTROGEN and PROGESTERONE DURING the MENSTRUAL CYCLE

1976 • 387 citations

Neurosteroids: Biosynthesis of Pregnenolone and Progesterone in Primary Cultures of Rat Glial Cells*

1989 • 372 citations

Neurosteroids: Cytochrome P-450 _scc in Rat Brain

1987 • 362 citations

CORRELATIONS BETWEEN THE CHEMICAL STRUCTURE AND THE PHARMACOLOGICAL ACTIONS OF THE STEROIDS¹

1942 • 348 citations

Anticonvulsant activity of neurosteroids: correlation with gamma-aminobutyric acid-evoked chloride current potentiation.

1994 • 343 citations

Characterization of steroid interactions with gamma-aminobutyric acid receptor-gated chloride ion channels: evidence for multiple steroid recognition sites.

1990 • 328 citations

Neurosteroids: oligodendrocyte mitochondria convert cholesterol to pregnenolone.

1987 • 294 citations

Neurosteroids: biochemistry, modes of action, and clinical relevance.

1994 • 271 citations

A key enzyme in the biosynthesis of neurosteroids, 3β-hydroxysteroid dehydrogenase/Δ5-Δ4-isomerase (3β-HSD), is expressed in rat brain

1995 • 207 citations

Effects of subunit types of the cloned GABAA receptor on the response to a neurosteroid

1991 • 174 citations

Avian neurosteroids. I. Pregnenolone biosynthesis in the quail brain

1995 • 153 citations

Neurosteroids modulate calcium currents in hippocampal CA1 neurons via a pertussis toxin-sensitive G-protein-coupled mechanism

1994 • 147 citations

Dehydroepiandrosterone is an anxiolytic in mice mice on the plus maze

1994 • 143 citations

GABAergic control of anterior pituitary hormone secretion

1982 • 133 citations

Immunocytochemical localization and biological activity of 3 beta- hydroxysteroid dehydrogenase in the central nervous system of the frog

1994 • 131 citations

Relationship Between Symptom Severity and Hormone Changes in Women With Premenstrual Syndrome*

1989 • 127 citations

The effect of progesterone and its metabolites on the interictal epileptiform discharge in the cat's cerebral cortex

1987 • 121 citations

Neurosteroidogenesis in Rat Retinas

1994 • 109 citations

Biosynthesis and assay of neurosteroids in rats and mice: Functional correlates

1995 • 109 citations

Pregnanolone emulsion A preliminary pharmacokinetic and pharmacodynamic study of a new intravenous anaesthetic agent

1990 • 108 citations

Avian neurosteroids. II. Localization of a cytochrome P450scc-like substance in the quail brain

1995 • 108 citations

Pregnenolone and pregnenolone sulfate, alone and with ethanol, in mice on the plus-maze

1994 • 90 citations

The Anaesthetic Potency of 3α‐Hydroxy‐5α‐pregnan‐20‐one and 3α‐Hydroxy‐5β‐pregnan‐20‐one Determined with an Intravenous EEG‐Threshold Method in Male Rats

1987 • 87 citations

Evidence for a role of neurosteroids in modulation of diurnal changes and acute stress-induced corticosterone secretion in rats

1995 • 83 citations

Evidence for a role for the neurosteroid allopregnanolone in the modulation of reproductive function in female rats

1995 • 80 citations

Steroid synthesis in rat brain cell cultures

1989 • 73 citations

Different γ-Aminobutyric Acid Receptor Subtypes are Involved in the Regulation of Opiate-Dependent and Independent Luteinizing Hormone-Releasing Hormone Secretion

1989 • 67 citations

Neurosteroids and brain function

1991 • 66 citations

γ-Aminobutyric Acid_AReceptors Mediate 3α-Hydroxy-5a-Pregnan-20-one-Induced Gonadotropin Secretion*

1990 • 59 citations

Dehydroepiandrosterone sulfate alters synaptic potentials in area CA1 of the hippocampal slice

1994 • 57 citations

Serum phenytoin, phenobarbital, carbamazepine, albumin; and plasma estradiol, progesterone concentrations during the menstrual cycle in women with epilepsy

2009 • 53 citations

Neuroendocrinology of Premenstrual Syndrome

1992 • 41 citations

Clinical and experimental studies on the role of GABA in the regulation of acth secretion: a review☆

1984 • 40 citations

GABA inhibits sexual behaviour in female rats

1988 • 36 citations

Epilepsy in women. Oestrogen and progesterone plasma levels

1976 • 35 citations

GABAergic drugs and lordosis behavior in the female rat

1989 • 29 citations

Gonadal sex hormones and dystonia: Experimental studies in genetically dystonic hamsters

1995 • 28 citations

Suppression in gonadotropes of gonadotropin-releasing hormone-stimulated follicle-stimulating hormone release by the gonadal- and neurosteroid 3 alpha-hydroxy-4-pregnen-20-one involves cytosolic calcium.

1994 • 25 citations

Potency of lipid and protein formulation of 5α-pregnanolone at induction of anaesthesia and the corresponding regional brain distribution

1995 • 25 citations

Neurosteroids and aggressive behaviour in Alzheimer's disease

1994 • 5 citations