Effect of Genetic Risk Factors and Disease Progression on the Cerebrospinal Fluid Tau Levels in Alzheimer's Disease

Clinical diagnosis of Alzheimer's disease

1984 • 27,279 citations

Gene Dose of Apolipoprotein E Type 4 Allele and the Risk of Alzheimer's Disease in Late Onset Families

1993 • 8,888 citations

Cloning of a gene bearing missense mutations in early-onset familial Alzheimer's disease

1995 • 3,985 citations

Candidate Gene for the Chromosome 1 Familial Alzheimer's Disease Locus

1995 • 2,548 citations

A68: a Major Subunit of Paired Helical Filaments and Derivatized Forms of Normal Tau

1991 • 1,397 citations

Immunochemical identification of the serine protease inhibitor α1-antichymotrypsin in the brain amyloid deposits of Alzheimer's disease

1988 • 899 citations

Tau protein and the neurofibrillary pathology of Alzheimer's disease

1993 • 710 citations

Reduction of β‐amyloid peptide₄₂ in the cerebrospinal fluid of patients with Alzheimer's disease

1995 • 684 citations

Alzheimer–associated presenilins 1 and 2 : Neuronal expression in brain and localization to intracellular membranes in mammalian cells

1996 • 549 citations

Detection of Proteins in Normal and Alzheimer's Disease Cerebrospinal Fluid with a Sensitive Sandwich Enzyme‐Linked Immunosorbent Assay

1993 • 481 citations

A4POE*4-associated Alzheimer's disease risk is modified by α1–antichymotrypsin polymorphism

1995 • 337 citations

Tau in cerebrospinal fluid: A potential diagnostic marker in Alzheimer's disease

1995 • 296 citations

Genetic association between intronic polymorphism in presenilin-1 gene and late-onset Alzheimer's disease

1996 • 244 citations

Elevation of microtubule-associated protein tau in the cerebrospinal fluid of patients with Alzheimer's disease

1995 • 223 citations

Increased cerebrospinal fluid tau in patients with Alzheimer's disease

1995 • 134 citations

Increasing cerebrospinal fluid tau levels in a subgroup of Alzheimer patients with apolipoprotein E allele ϵ4 during 14 months follow-up

1996 • 69 citations

Presenilin-1 polymorphism and Alzheimer's disease

1996 • 66 citations

Expression of apolipoprotein E in normal and diverse neurodegenerative disease brain

1996 • 45 citations

Apolipoprotein E and α₁‐antichymotrypsin polymorphism in Alzheimer's disease

1996 • 36 citations

?1-Antichymotrypsin gene polymorphism and risk for Alzheimer's disease

1996 • 33 citations