Ca2+ transients and Mn2+ entry in human neutrophils induced by thapsigargin

A new generation of Ca2+ indicators with greatly improved fluorescence properties.

1985 • 21,873 citations

Studies and Perspectives of Protein Kinase C

1986 • 5,148 citations

A model for receptor-regulated calcium entry

1986 • 2,535 citations

Thapsigargin, a novel molecular probe for studying intracellular calcium release and storage

1989 • 583 citations

Ion channels in human neutrophils activated by a rise in free cytosolic calcium concentration

1986 • 489 citations

A novel tumour promoter, thapsigargin, transiently increases cytoplasmic free Ca2+ without generation of inositol phosphates in NG115-401L neuronal cells

1988 • 344 citations

Phosphoinositides and receptor mechanisms

1987 • 320 citations

Agonists stimulate divalent cation channels in the plasma membrane of human platelets

1985 • 303 citations

Stimulus response coupling in the human neutrophil. II. Temporal analysis of changes in cytosolic calcium and calcium efflux.

1984 • 272 citations

Physiological [Ca2+]i level and pump-leak turnover in intact red cells measured using an incorporated Ca chelator

1982 • 251 citations

Phorbol esters inhibit the fMet-Leu-Phe- and leukotriene B4-stimulated calcium mobilization and enzyme secretion in rabbit neutrophils.

1985 • 196 citations

Phorbol myristate acetate stimulates ATP-dependent calcium transport by the plasma membrane of neutrophils.

1984 • 193 citations

Long-term phorbol ester treatment down-regulates protein kinase C and sensitizes the phosphoinositide signaling pathway to hormone and growth factor stimulation. Evidence for a role of protein kinase C in agonist-induced desensitization.

1988 • 186 citations

The calcium mobilizing and tumor promoting agent, thapsigargin elevates the platelet cytoplasmic free calcium concentration to a higher steady state level. A possible mechanism of action for the tumor promotion

1987 • 144 citations

The Ca2+ Pump of Plasma Membranes

2018 • 119 citations

Irreversible ATP depletion caused by low concentrations of formaldehyde and of calcium-chelator esters in intact human red cells

1984 • 114 citations

The ability of thapsigargin and thapsigargicin to activate cells involved in the inflammatory response

1985 • 107 citations

Isolation of large numbers of fully viable human neutrophils: a preparative technique using percoll density gradient centrifugation.

1982 • 87 citations

Evidence that phorbol ester interferes with stimulated Ca2+ redistribution by activating Ca2+ efflux in neutrophil leucocytes

1985 • 76 citations

Hysteretic activation of the Ca2+ pump revealed by calcium transients in human red cells

1983 • 68 citations

Phorbol ester-induced changes of cytoplasmic pH in neutrophils: role of exocytosis in Na+-H+ exchange

1985 • 64 citations

Effect of cytochalasins on cytosolic-free calcium concentration and phosphoinositide metabolism in leukocytes

1987 • 59 citations

Effect of thapsigargin on cytoplasmic Ca2+ and proliferation of human lymphocytes in relations to AIDS

1988 • 55 citations

Rate constants for calmodulin binding to Ca2+-ATPase in erythrocyte membranes

1982 • 54 citations

Adenosine triphosphate-dependent calcium pump in the plasma membrane of guinea pig and human neutrophils.

1984 • 50 citations

Role of cytosolic free calcium and phospholipase C in leukotrien‐B4‐stimulated secretion in human neutrophils

1987 • 45 citations

Temporal association of calcium mobilization, inositol trisphosphate generation, and superoxide anion release by human neutrophils activated by serum opsonized and nonopsonized particulate stimuli

1988 • 30 citations

Delayed activation of calcium pump during transient increases in cellular Ca2+ concentration and K+ conductance in hyperpolarizing human red cells

1986 • 21 citations

Effect of thapsigargin on cytoplasmic Ca2+ and proliferation of human lymphocytes in relation to AIDS

1988 • 18 citations

Lack of correlation between calcium mobilization and respiratory burst activation induced by chemotactic factors in rabbit polymorphonuclear leukocytes

1987 • 16 citations