Hypercontractile Properties of Cardiac Muscle Fibers in a Knock-in Mouse Model of Cardiac Myosin-binding Protein-C

Scatter factor/hepatocyte growth factor is essential for liver development

1995 • 1,398 citations

Mutations in the Gene for Cardiac Myosin-Binding Protein C and Late-Onset Familial Hypertrophic Cardiomyopathy

1998 • 759 citations

A new protein of the thick filaments of vertebrate skeletal myofibrils

1973 • 615 citations

Mutations in the cardiac myosin binding protein–C gene on chromosome 11 cause familial hypertrophic cardiomyopathy

1995 • 574 citations

Familial Hypertrophic Cardiomyopathy

1998 • 427 citations

Phosphorylation switches specific for the cardiac isoform of myosin binding protein-C: a modulator of cardiac contraction?

1995 • 400 citations

α-cardiac actin is a novel disease gene in familial hypertrophic cardiomyopathy

1999 • 394 citations

Organization and Sequence of Human Cardiac Myosin Binding Protein C Gene (MYBPC3) and Identification of Mutations Predicted to Produce Truncated Proteins in Familial Hypertrophic Cardiomyopathy

1997 • 295 citations

Clinical Features and Prognostic Implications of Familial Hypertrophic Cardiomyopathy Related to the Cardiac Myosin-Binding Protein C Gene

1998 • 282 citations

A Molecular Map of the Interactions between Titin and Myosin‐Binding Protein C

1996 • 272 citations

Dilated cardiomyopathy in homozygous myosin-binding protein-C mutant mice

1999 • 258 citations

I-Band Titin in Cardiac Muscle Is a Three-Element Molecular Spring and Is Critical for Maintaining Thin Filament Structure

1999 • 237 citations

Mutations in β-myosin S2 that cause familial hypertrophic cardiomyopathy (FHC) abolish the interaction with the regulatory domain of myosin-binding protein-C 1 1Edited by J. Karn

1999 • 233 citations

Myosin Binding Protein C, a Phosphorylation-Dependent Force Regulator in Muscle That Controls the Attachment of Myosin Heads by Its Interaction With Myosin S2

2000 • 223 citations

Genomic DNA microextraction: A method to screen numerous samples

1992 • 221 citations

A mouse model of myosin binding protein C human familial hypertrophic cardiomyopathy.

1998 • 198 citations

Alterations in Ca2+ sensitive tension due to partial extraction of C-protein from rat skinned cardiac myocytes and rabbit skeletal muscle fibers.

1991 • 192 citations

The ultrastructural location of C-protein, X-protein and H-protein in rabbit muscle

1986 • 188 citations

cAPK‐phosphorylation controls the interaction of the regulatory domain of cardiac myosin binding protein C with myosin‐S2 in an on‐off fashion

1999 • 185 citations

Alteration of myosin cross bridges by phosphorylation of myosin-binding protein C in cardiac muscle.

1996 • 183 citations

Protein kinase C-mediated phosphorylation of troponin I and C-protein in isolated myocardial cells is associated with inhibition of myofibrillar actomyosin MgATPase.

1993 • 178 citations

A Mutant Tropomyosin That Causes Hypertrophic Cardiomyopathy Is Expressed In Vivo and Associated With an Increased Calcium Sensitivity

1998 • 172 citations

Hypertrophic cardiomyopathy without hypertrophy: two families with myocardial disarray in the absence of increased myocardial mass.

1990 • 166 citations

Cardiac Myosin Binding Protein C

1999 • 162 citations

Phosphorylation of purified cardiac muscle C-protein by purified cAMP-dependent and endogenous Ca2+-calmodulin-dependent protein kinases.

1984 • 155 citations

The C-proteins of rabbit red, white, and cardiac muscles.

1983 • 129 citations

Complete sequence of human fast‐type and slow‐type muscle myosin‐binding‐protein C (MyBP‐C)

1993 • 120 citations

In Vivo Modeling of Myosin Binding Protein C Familial Hypertrophic Cardiomyopathy

1999 • 101 citations

Identification of the A-band localization domain of myosin binding proteins C and H (MyBP-C, MyBP-H) in skeletal muscle

1999 • 94 citations

Phosphorylation of chicken cardiac C-protein by calcium/calmodulin-dependent protein kinase II.

1991 • 90 citations

Effects of phosphorylation of troponin I and C protein on isometric tension and velocity of unloaded shortening in skinned single cardiac myocytes from rats.

1994 • 88 citations

Localization of C-protein isoforms in chicken skeletal muscle: ultrastructural detection using monoclonal antibodies.

1984 • 85 citations

Effects of Two Hypertrophic Cardiomyopathy Mutations in α-Tropomyosin, Asp175Asn and Glu180Gly, on Ca2+Regulation of Thin Filament Motility

1997 • 77 citations

COOH-terminal truncated cardiac myosin-binding protein C mutants resulting from familial hypertrophic cardiomyopathy mutations exhibit altered expression and/or incorporation in fetal rat cardiomyocytes

1999 • 73 citations

Isoform-specific Interaction of the Myosin-binding Proteins (MyBPs) with Skeletal and Cardiac Myosin Is a Property of the C-terminal Immunoglobulin Domain

1997 • 62 citations

Cyclic AMP inhibits contractility of detergent treated glycerol extracted cardiac muscle

1981 • 61 citations

A novel isoform of the smooth muscle cell differentiation marker smoothelin

1999 • 54 citations

Myosin Binding Protein C, a Potential Regulator of Cardiac Contractility

2000 • 53 citations

Reconstitution of skinned cardiac fibres with human recombinant cardiac troponin‐I mutants and troponin‐C

1995 • 43 citations