An analysis of randomized trials evaluating the effect of cholesterol reduction on total mortality and coronary heart disease incidence.

Blood pressure, stroke, and coronary heart disease *1Part 1, prolonged differences in blood pressure: prospective observational studies corrected for the regression dilution bias

1990 • 4,310 citations

Helsinki Heart Study: Primary-Prevention Trial with Gemfibrozil in Middle-Aged Men with Dyslipidemia

1987 • 3,889 citations

Fifteen year mortality in Coronary Drug Project patients: Long-term benefit with niacin

1986 • 1,857 citations

Clofibrate and Niacin in Coronary Heart Disease

1975 • 1,660 citations

EFFECT OF DIET AND SMOKING INTERVENTION ON THE INCIDENCE OF CORONARY HEART DISEASE

1981 • 1,050 citations

Methods for combining randomized clinical trials: Strengths and limitations

1987 • 998 citations

A note on graphical presentation of estimated odds ratios from several clinical trials

1988 • 632 citations

A Controlled Clinical Trial of a Diet High in Unsaturated Fat in Preventing Complications of Atherosclerosis

1969 • 600 citations

CONTROLLED TRIAL OF SOYA-BEAN OIL IN MYOCARDIAL INFARCTION

1968 • 473 citations

Colestipol hydrochloride in hypercholesterolemic patients—Effect on serum cholesterol and mortality

1978 • 208 citations

Corn Oil in Treatment of Ischaemic Heart Disease

1965 • 189 citations

Low Fat, Low Cholesterol Diet in Secondary Prevention of Coronary Heart Disease

1978 • 172 citations

Bias in the one‐step method for pooling study results

1990 • 165 citations

Multifactorial Primary Prevention of Cardiovascular Diseases in Middle-aged Men

1985 • 154 citations

Coronary heart disease death, nonfatal acute myocardial infarction and other clinical outcomes in the multiple risk factor intervention trial

1986 • 107 citations

Reduction of myocardial reinfarction by the combined treatment with clofibrate and nicotinic acid

1977 • 106 citations

Multifactorial trial in the prevention of coronary heart disease: 3. Incidence and mortality results

1983 • 99 citations

The Oslo study: Diet and antismoking advice. Additional results from a 5-year primary preventive trial in middle-aged men

1985 • 81 citations

Controlled trial of clofibrate in cerebral vascular disease

1972 • 75 citations

A sustained delivery system for intramuscular administration of lipophilic drugs using globular partially quaternised poly[thio-1-(N,N-diethyl aminomethyl)-1-ethylene]

1986 • 12 citations