Acute hemodynamic responses to vasodilator therapy in congestive heart failure

The Pharmacological Basis of Therapeutics

1976 • 1,403 citations

Hemodynamic Determinants of Oxygen Consumption of the Heart With Special Reference to the Tension-Time Index

1957 • 1,328 citations

THE EFFECT OF CORONARY OCCLUSION ON MYOCARDIAL CONTRACTION

1935 • 1,133 citations

Defective Cardiac Parasympathetic Control in Patients with Heart Disease

1971 • 971 citations

The Renin-Angiotensin System

1978 • 969 citations

Plasma norepinephrine in congestive heart failure

1978 • 919 citations

Control of myocardial oxygen consumption

1971 • 799 citations

Afterload mismatch and preload reserve: A conceptual framework for the analysis of ventricular function

1976 • 634 citations

Localized Disorders in Myocardial Contraction

1967 • 625 citations

Catecholamine excretion and cardiac stores of norepinephrine in congestive heart failure

1965 • 573 citations

Use of plasma norepinephrine for evaluation of sympathetic neuronal function in man

1976 • 548 citations

Relation of the renin-angiotensin-aldosterone system to clinical state in congestive heart failure.

1981 • 534 citations

Angiotensin-converting enzyme inhibitors from the venom of Bothrops jararaca. Isolation, elucidation of structure, and synthesis

1971 • 516 citations

Contractile State of Cardiac Muscle Obtained from Cats with Experimentally Produced Ventricular Hypertrophy and Heart Failure

1967 • 505 citations

Vasodilator Therapy of Cardiac Failure

1977 • 487 citations

Mechanism of tolerance development to organic nitrates.

1973 • 486 citations

IMPROVED LEFT VENTRICULAR FUNCTION DURING NITROPRUSSIDE INFUSION IN ACUTE MYOCARDIAL INFARCTION

1972 • 461 citations

Left ventricular compliance: Mechanisms and clinical implications

1976 • 458 citations

Augmentation of the Plasma Nor-Epinephrine Response to Exercise in Patients with Congestive Heart Failure

1962 • 443 citations

Circulatory adjustments to dynamic exercise and effect of physical training in normal subjects and in patients with coronary artery disease

1976 • 438 citations

The Effects of Nitroglycerin and Amyl Nitrite on Arteriolar and Venous Tone in the Human Forearm

1965 • 430 citations

SELECTIVITY OF BLOCKING AGENTS FOR PRE‐ AND POSTSYNAPTIC α‐ADRENOCEPTORS

1977 • 424 citations

Hemodynamic and Metabolic Responses to Vasodilator Therapy in Acute Myocardial Infarction

1973 • 421 citations

Role of the renin-angiotensin system in the systemic vasoconstriction of chronic congestive heart failure.

1978 • 396 citations

Effects of changes in preload, afterload and inotropic state on ejection and isovolumic phase measures of contractility in the conscious dog

1975 • 388 citations

Sustained Effectiveness of Converting-Enzyme Inhibition in Patients with Severe Congestive Heart Failure

1980 • 380 citations

Effect of Ischemia and Antianginal Drugs on the Distribution of Radioactive Microspheres in the Canine Left Ventricle

1971 • 379 citations

Treatment of Refractory Heart Failure with Infusion of Nitroprusside

1974 • 375 citations

Arterial impedance as ventricular afterload.

1975 • 369 citations

Comparison between the effects of nitroprusside and nitroglycerin on ischemic injury during acute myocardial infarction.

1976 • 368 citations

Mechanisms of Contraction of the Normal and Failing Heart.

1976 • 367 citations

A comparison of the effects of vasodilator stimuli on peripheral resistance vessels in normal subjects and in patients with congestive heart failure

1968 • 367 citations

Cardiovascular Effects of Angiotensin Mediated by the Central Nervous System

1972 • 362 citations

The action of peptides on the adrenal medulla. Release of adrenaline by bradykinin and angiotensin

1964 • 361 citations

EDEMA AND DECREASED RENAL BLOOD FLOW IN PATIENTS WITH CHRONIC CONGESTIVE HEART FAILURE: EVIDENCE OF “FORWARD FAILURE” AS THE PRIMARY CAUSE OF EDEMA 1

1946 • 353 citations

Captopril-induced Changes in Prostaglandin Production

1980 • 340 citations

Human Splanchnic and Forearm Vasoconstrictor Responses to Reductions of Right Atrial and Aortic Pressures

1974 • 334 citations

A SPECIFIC ORALLY ACTIVE INHIBITOR OF ANGIOTENSIN-CONVERTING ENZYME IN MAN

1977 • 332 citations

Impaired left ventricular relaxation during pacing-induced ischemia

1973 • 331 citations

Studies on Digitalis. X. Effects of Ouabain on Forearm Vascular Resistance and Venous Tone in Normal Subjects and in Patients in Heart Failure *

1964 • 323 citations

Nitroglycerin to Unmask Reversible Asynergy Correlation with Post Coronary Bypass Ventriculography

1974 • 323 citations

The role of vasodilator therapy in heart failure

1977 • 316 citations

Intravenous nitroglycerin in acute myocardial infarction.

1975 • 315 citations

Beneficial Effects of Vasodilator Agents in Severe Mitral Regurgitation Due to Dysfunction of Subvalvar Apparatus

1973 • 314 citations

The role of low pressure baroreceptors in reflex vasoconstrictor responses in man

1972 • 314 citations

Experimental Myocardial Infarction

1961 • 313 citations

Regional Myocardial function in the conscious dog during acute coronary occlusion and responses to morphine, propranolol, nitroglycerin, and lidocaine.

1976 • 310 citations

The Renin-Angiotensin System

1974 • 307 citations

Vasodilator Therapy for Heart Failure

1973 • 301 citations

Influence of Right Ventricular Filling Pressure on Left Ventricular Pressure and Dimension

1974 • 299 citations

Oral hydralazine therapy for chronic refractory heart failure.

1976 • 299 citations

The renin-angiotensin-aldosterone system in congestive failure in conscious dogs.

1976 • 297 citations

Effect of Nitroglycerin on the Coronary Circulation in Patients with Coronary Artery Disease or Increased Left Ventricular Work

1959 • 291 citations

Immediate and sustained hemodynamic and clinical improvement in chronic heart failure by an oral angiotensin-converting enzyme inhibitor.

1980 • 291 citations

PHENTOLAMINE FOR VASODILATOR TREATMENT OF SEVERE HEART-FAILURE

1971 • 282 citations

Control of myocardial oxygen consumption: relative influence of contractile state and tension development

1968 • 278 citations

Sodium Nitroprusside

1975 • 277 citations

Hemodynamics at rest and during supine and sitting bicycle exercise in normal subjects

1978 • 275 citations

Myocardial Norepinephrine Concentration in Man

1963 • 274 citations

Treatment of Chronic Congestive Heart Failure with Captopril, an Oral Inhibitor of Angiotensin-Converting Enzyme

1979 • 271 citations

Accentuated Vascular and Endocrine Response to Sq 20881 in Hypertension

1977 • 270 citations

Effect of nitrates and other coronary dilators on large and small coronary vessels: an hypothesis for the mechanism of action of nitrates.

1969 • 268 citations

Pharmacological mechanisms for left ventricular unloading in clinical congestive heart failure. Differential effects of nitroprusside, phentolamine, and nitroglycerin on cardiac function and peripheral circulation.

1976 • 264 citations

Sustained Reduction of Cardiac Impedance and Preload in Congestive Heart Failure with the Antihypertensive Vasodilator Prazosin

1977 • 262 citations

Acute and long-term response to an oral converting-enzyme inhibitor, captopril, in congestive heart failure.

1980 • 258 citations

Relationship of acetyl transferase activity to antinuclear antibodies and toxic symptoms in hypertensive patients treated with hydralazine.

1970 • 257 citations

Alpha-Adrenergic Receptor Subtypes

1980 • 255 citations

Sulfhydryl requirement for relaxation of vascular smooth muscle.

1973 • 254 citations

Cardiovascular Actions of Sodium Nitroprusside in Animals and Hypertensive Patients

1955 • 254 citations

Hemodynamic Effects of Orally Administered Isosorbide Dinitrate in Patients with Congestive Heart Failure

1974 • 247 citations

Hemodynamic and clinical tachyphylaxis to prazosin-mediated afterload reduction in severe chronic congestive heart failure.

1979 • 246 citations

Afterload as a primary determinant of ventricular performance

1963 • 243 citations

Use of Sublingual Nitroglycerin in Congestive Failure following Acute Myocardial Infarction

1972 • 240 citations

Angiotensin converting enzyme inhibition in patients with congestive heart failure.

1978 • 238 citations

Effects of angiotensin, vasopressin, and methoxamine on cardiac function and blood flow distribution in conscious dogs

1976 • 236 citations

A Comparison of Regional Blood Flow and Oxygen Utilization During Dynamic Forearm Exercise in Normal Subjects and Patients with Congestive Heart Failure

1974 • 233 citations

Studies on myocardial metabolism

1956 • 227 citations

Alterations in the Baroreceptor Reflex in Conscious Dogs with Heart Failure

1972 • 225 citations

Gerald Legh Malins McElligott.

1972 • 223 citations

Importance of the adrenergic nervous system in the support of circulatory function in patients with congestive heart failure

1963 • 218 citations

Hemodynamic Improvement after Oral Hydralazine in Left Ventricular Failure

1977 • 213 citations

Studies on Cardiac Dimensions in Intact, Unanesthetized Man

1963 • 210 citations

Impairment of autonomically mediated heart rate control in patients with cardiac dysfunction.

1975 • 205 citations

Failure of Intracoronary Nitroglycerin to Alleviate Pacing-Induced Angina

1972 • 202 citations

Hydralazine

1976 • 201 citations

Relationship of plasma volume changes to resistance and capacitance vessel effects of sympathomimetic amines and angiotensin in man.

1966 • 199 citations

Prazosin

1979 • 198 citations

Cardiac Norepinephrine Stores in Experimental Heart Failure in the Dog*

1964 • 197 citations

A COORDINATED APPROACH TO CHILDREN'S HEALTH IN INDIA

1981 • 197 citations

Tolerance to the circulatory effects of oral isosorbide dinitrate. Rate of development and cross-tolerance to glyceryl trinitrate.

1980 • 196 citations

Myocardial mechanics in aortic and mitral valvular regurgitation: the concept of instantaneous impedance as a determinant of the performance of the intact heart

1968 • 194 citations

Effect of nitroprusside on regional myocardial blood flow in coronary artery disease. Results in 25 patients and comparison with nitroglycerin.

1978 • 193 citations

Clinical use of sodium nitroprusside in chronic ischemic heart disease. Effects on peripheral vascular resistance and venous tone and on ventricular volume, pump and mechanical performance.

1975 • 193 citations

Long-term therapy of heart failure with prazosin: A randomized double blind trial

1980 • 183 citations

Experimental myocardial infarction

1970 • 181 citations

Afterload reduction and cardiac performance

1978 • 180 citations

IMPROVEMENT OF CHRONIC CONGESTIVE HEART-FAILURE BY ORAL CAPTOPRIL

1979 • 180 citations

Acute regional circulatory and renal hemodynamic effects of converting-enzyme inhibition in patients with congestive heart failure.

1981 • 179 citations

Dynamic aspects of acute mitral regurgitation: effects of ventricular volume, pressure and contractility on the effective regurgitant orifice area.

1979 • 179 citations

Converting enzyme inhibition in essential hypertension: the hypotensive response does not reflect only reduced angiotensin II formation.

1979 • 177 citations

Renin relationships in congestive cardiac failure, treated and untreated

1970 • 176 citations

Vasodilator therapy in acute myocardial infarction. A comparison of sodium nitroprusside and nitroglycerin.

1975 • 176 citations

Hemodynamic advantage of combined administration of hydralazine orally and nitrates nonparenterally in the vasodilator therapy of chronic heart failure

1977 • 173 citations

Pharmacokinetic-hemodynamic studies of intravenous nitroglycerin in congestive cardiac failure.

1980 • 173 citations

Efficacy of ambulatory systemic vasodilator therapy with oral prazosin in chronic refractory heart failure. Concomitant relief of pulmonary congestion and elevation of pump output demonstrated by improvements in symptomatology, exercise tolerance, hemodynamics and echocardiography.

1977 • 173 citations

Nitrate Therapy for Congestive Heart Failure

1978 • 173 citations

Response of plasma norepinephrine and epinephrine to dynamic exercise in patients with congestive heart failure

1982 • 171 citations

Left Ventricular Performance During Muscular Exercise in Patients with and without Cardiac Dysfunction

1966 • 169 citations

Hemodynamic Effects of Quantitatively Varied Experimental Aortic Regurgitation

1957 • 169 citations

Hemodynamic effects of nitroglycerin in acute myocardial infarction.

1975 • 168 citations

The Mechanism of Adaptation of Left Atrial Stretch Receptors in Dogs with Chronic Congestive Heart Failure

1977 • 166 citations

Release of norepinephrine and dopamine-beta-hydroxylase by nerve stimulation. I. Role of neuronal and extraneuronal uptake and of alpha presynaptic receptors.

1974 • 165 citations

Blockade and stimulation of renal, adrenal, and vascular angiotensin II receptors with 1-Sar, 8-Ala angiotensin II in normal man.

1976 • 165 citations

Sustained hemodynamic effects without tolerance during long-term isosorbide dinitrate treatment of chronic left ventricular failure

1980 • 164 citations

Action of Nitroglycerin on the Coronary Circulation in Normal and in Mild Cardiac Subjects

1959 • 164 citations

Studies on Cardiac Dimensions in Intact Unanesthetized Man

1965 • 164 citations

Hemodynamic and metabolic effects of isosorbide dinitrate in chronic congestive heart failure

1975 • 161 citations

The Hemodynamic Effects of Hypotensive Drugs in Man

1953 • 160 citations

Effect of angina on the left ventricular diastolic pressure-volume relationship.

1977 • 159 citations

Nature of the Inotropic Action of Angiotensin on Ventricular Myocardium

1965 • 159 citations

Mechanism of Norepinephrine Depletion in Experimental Heart Failure Produced by Aortic Constriction in the Guinea Pig

1965 • 157 citations

Mechanism of reduction of mitral regurgitation with vasodilator therapy

1979 • 157 citations

Mechanism for the postive inotropic effect of angiotensin II on isolated cardiac muscle.

1976 • 156 citations

Characterization of the Circulatory Response to Maximal Upright Exercise in Normal Subjects and Patients with Heart Disease

1967 • 155 citations

Partition of Blood Flow to the Cutaneous and Muscular Beds of the Forearm at Rest and during Leg Exercise in Normal Subjects and in Patients with Heart Failure

1969 • 154 citations

Blood levels after sublingual nitroglycerin.

1979 • 153 citations

Effects of sodium nitroprusside on left ventricular diastolic pressure-volume relations.

1977 • 152 citations

Effect of nitroglycerin on exercise-induced abnormalities of left ventricular regional function and ejection fraction in coronary artery disease. Assessment by radionuclide clineagiography in symptomatic and asymptomatic patients.

1978 • 152 citations

Effects of Nitroglycerin on Regional Myocardial Blood Flow in Coronary Artery Disease

1971 • 151 citations

Inhibition of Pressor Effects of Angiotensin I and Augmentation of Depressor Effects of Bradykinin by Synthetic Peptides

1972 • 146 citations

A study of the mechanism of the hemodynamic effects of hydralazine in man.

1963 • 145 citations

Hemodynamic consequences of afterload reduction in patients with chronic aortic regurgitation.

1976 • 144 citations

Effects of Norepinephrine on Coronary Circulation and Left Ventricular Dynamics in the Conscious Dog

1974 • 144 citations

Aortic input impedance in heart failure.

1978 • 143 citations

Impaired Atrial Receptor Responses in Dogs with Heart Failure Due to Tricuspid Insufficiency and Pulmonary Artery Stenosis

1973 • 143 citations

Angiotensin converting enzyme inhibition in patients with congestive heart failure.

1978 • 143 citations

Noninvasive assessment of load reduction in patients with asymptomatic aortic regurgitation

1980 • 143 citations

Mode of action of sodium nitroprusside on vascular smooth muscle

1975 • 139 citations

Nitroglycerin and Long-Acting Nitrates

1980 • 138 citations

Differential Response of Large and Small Coronary Arteries to Nitroglycerin and Angiotensin

1973 • 138 citations

Combined Oral Hydralazine-Nitrate Therapy in Left Ventricular Failure

1978 • 137 citations

Beneficial effects of hydralazine in severe mitral regurgitation.

1978 • 137 citations

The Kidney in Heart Failure

1977 • 137 citations

Hemodynamic effects of nitroglycerin ointment in congestive heart failure

1976 • 137 citations

Mechanism for Flow Distribution in Normal and Ischemic Myocardium during Increased Ventricular Preload in the Dog

1973 • 136 citations

Influence of right ventricular hemodynamics on left ventricular diastolic pressure-volume relations in man.

1979 • 135 citations

Extent of Regulation of the Heart's Contractile State in the Conscious Dog by Alteration in the Frequency of Contraction

1973 • 134 citations

Reduction of the Cardiac Response to Postganglionic Sympathetic Nerve Stimulation in Experimental Heart Failure

1966 • 134 citations

Effect of Nitroprusside on Left Ventricular Dynamics in Mitral Regurgitation

1974 • 134 citations

Vasodilator therapy for chronic left ventricular failure.

1976 • 134 citations

Hydralazine elimination in man

1973 • 133 citations

Myocardial Actions of Angiotensin

1964 • 132 citations

Hemodynamic assessment of oral peripheral vasodilator therapy in chronic congestive heart failure: Prolonged effectiveness of isosorbide dinitrate

1977 • 129 citations

The Circulatory Effects of Intravenous Phentolamine in Man

1965 • 129 citations

Direct myocardial effects of angiotensin II

1971 • 128 citations

Comparative hemodynamic effects of inotropic and vasodilator drugs in severe heart failure.

1977 • 128 citations

AN ESTIMATION OF THE HEPATIC BLOOD FLOW AND SPLANCHNIC OXYGEN CONSUMPTION IN HEART FAILURE 1

1948 • 126 citations

Use of Phentolamine in Acute Myocardial Infarction Associated with Hypertension and Left Ventricular Failure

1973 • 126 citations

Influence of reduction of preload and afterload by nitroglycerin on left ventricular diastolic pressure-volume relations and relaxation in man.

1977 • 125 citations

Effect of a new angiotensin converting enzyme inhibitor MK 421 and its lysine analogue on the components of the renin system in healthy subjects.

1981 • 124 citations

Improvement in left ventricular wall motion following nitroglycerin.

1975 • 124 citations

Attenuation of Prazosin Effect on Cardiac Output in Chronic Heart Failure

1979 • 123 citations

Abnormalities in the regional circulations accompanying congestive heart failure

1975 • 123 citations

Nitroprusside

1979 • 123 citations

Rebound Hemodynamic Events after the Abrupt Withdrawal of Nitroprusside in Patients with Severe Chronic Heart Failure

1979 • 122 citations

Effects of intravenous nitroglycerin on left ventricular function and ST segment changes in acute myocardial infarction.

1976 • 120 citations

Release of Adrenal Catecholamines by Angiotensin II

1966 • 119 citations

Some Effects of Nitroglycerin upon the Splanchnic, Pulmonary, and Systemic Circulations

1966 • 117 citations

CARDIOVASCULAR AND RENAL ADJUSTMENTS TO A HYPOTENSIVE AGENT

1952 • 117 citations

The role of renin and aldosterone in the salt retention of edema

1977 • 115 citations

Central and regional hemodynamic effects of intravenous isosorbide dinitrate, nitroglycerin and nitroprusside in patients with congestive heart failure

1981 • 115 citations

Comparison of effects of nitroprusside and prazosin on left ventricular function and the peripheral circulation in chronic refractory congestive heart failure.

1978 • 115 citations

Effect of a new angiotensin converting enzyme inhibitor MK 421 and its lysine analogue on the components of the renin system in healthy subjects

2004 • 114 citations

Reduced Systemic Vascular Resistance as Therapy for Severe Mitral Regurgitation of Valvular Origin

1975 • 114 citations

The effect of nitroglycerin on coronary blood flow and the hemodynamic response to exercise in coronary artery disease

1971 • 114 citations

Norepinephrine Stores and Contractile Force of Papillary Muscle from the Failing Human Heart

1966 • 113 citations

Effect of prazosin vs placebo on chronic left ventricular heart failure.

1979 • 112 citations

Arterial Sodium Content in Experimental Congestive Heart Failure

1970 • 111 citations

Oral isosorbide dinitrate in the treatment of angina pectoris. Dose-response relationship and duration of action during acute therapy.

1980 • 111 citations

Alpha blocking action of the antihypertensive agent, prazosin.

1977 • 110 citations

Effects of nitroglycerin on the major determinants of myocardial oxygen consumption

1975 • 109 citations

Phentolamine and cardiovascular performance.

1969 • 108 citations

Pharmacokinetic-hemodynamic studies of nitroglycerin ointment in congestive heart failure

1980 • 108 citations

Aortic Input Impedance during Nitroprusside Infusion

1979 • 108 citations

Hemodynamic and metabolic effects of sodium nitroprusside on the performance and metabolism of regional ischemic myocardium;.

1975 • 107 citations

Afterload reduction therapy with nitroprusside in severe aortic regurgitation: Improved cardiac performance and reduced regurgitant volume

1976 • 107 citations

Energetics of the human heart∗

1962 • 107 citations

Left Ventricular Stiffness Associated with Chronic Pressure and Volume Overloads in Man

1974 • 105 citations

Cardiac Norepinephrine Stores and the Contractile State of Heart Muscle

1966 • 105 citations

Hemodynamics at rest and during exercise after oral hydralazine in patients with cor pulmonale

1981 • 105 citations

Marked early attenuation of hemodynamic effects of oral prazosin therapy in chronic congestive heart failure

1979 • 105 citations

LOW-DOSE CAPTOPRIL IN CHRONIC HEART FAILURE: ACUTE HAEMODYNAMIC EFFECTS AND LONG-TERM TREATMENT

1980 • 104 citations

Nitrate effects on cardiac output and left ventricular outflow resistance in chronic congestive heart failure

1978 • 104 citations

Effects of nitroglycerin on left ventricular cavitary size and cardiac performance determined by ultrasound in man

1974 • 104 citations

Response of the kallikrein-kinin and renin-angiotensin systems to saline infusion and upright posture.

1975 • 103 citations

Chronic Vasodilator Therapy in the Management of Cardiogenic Shock and Intractable Left Ventricular Failure

1974 • 102 citations

Paradox of improved exercise but not resting hemodynamics with short-term prazosin in chronic heart failure

1979 • 102 citations

Beneficial effects of hydralazine on rest and exercise hemodynamics in patients with chronic severe aortic insufficiency.

1980 • 100 citations

Endocrine factors in congestive heart failure

1968 • 100 citations

Differences in Direct Effects of Adrenergic Stimuli on Coronary, Cutaneous, and Muscular Vessels

1972 • 99 citations

STUDIES ON HYDRALAZINE; EVIDENCE FOR A PERIPHERAL SITE OF ACTION 1

1954 • 99 citations

Peripheral Venoconstriction in Human Congestive Heart Failure

1956 • 99 citations

Angiotensin inhibition in severe heart failure: Acute central and limb hemodynamic effects of captopril with observations on sustained oral therapy

1981 • 99 citations

Systemic and coronary hemodynamic effects of sodium nitroprusside

1974 • 99 citations

Left Ventricular Volume Changes After Amyl Nitrite and Nitroglycerin in Man as Measured by Ultrasound

1974 • 98 citations

Determinants of drug response in severe chronic heart failure. 1. Activation of vasoconstrictor forces during vasodilator therapy.

1981 • 98 citations

Dose requirements of hydralazine in patients with severe chronic congestive heart failure

1980 • 97 citations

Coronary and Myocardial Actions of Angiotensin

1964 • 97 citations

Augmented Sympathetic Neurotransmitter Activity in the Peripheral Vascular Bed of Patients with Congestive Heart Failure and Cardiac Norepinephrine Depletion

1968 • 96 citations

Importance of Left Ventricular Chamber Size in Determining the Response to Hydralazine in Severe Chronic Heart Failure

1980 • 96 citations

Comparison of Direct Effects of Angiotensin and Other Vasoactive Agents on Small and Large Blood Vessels in Several Vascular Beds

1962 • 95 citations

Quantitative determination of trinitroglycerin in human plasma.

1979 • 94 citations

Immediate effects of hydralazine-isosorbide dinitrate combination on exercise capacity and exercise hemodynamics in patients with left ventricular failure.

1979 • 94 citations

Effects of nitroglycerin on cardiac function and regional blood flow distribution in conscious dogs

1978 • 93 citations

Comparison of Effects of Angiotensin and Norepinephrine on Pulmonary Circulation, Systemic Arteries and Veins, and Systemic Vascular Capacity in the Dog

1962 • 93 citations

Hemodynamic Effects of Quantitatively Varied Experimental Mitral Regurgitation

1957 • 93 citations

Hemodynamic effects of intravenous sodium nitroprusside in the conscious dog.

1978 • 93 citations

Comparative hemodynamic effects of chewable isosorbide dinitrate and nitroglycerin in patients with congestive heart failure.

1975 • 92 citations

The Effects of Intravenous Apresoline (Hydralazine) on Cardiovascular and Renal Function in Patients with and without Congestive Heart Failure

1956 • 91 citations

Renal Hyperemia Induced in Man by a New Phthalazine Derivative

1950 • 91 citations

Analysis of the hypotensive action of prazosin.

1975 • 91 citations

Orally administered isosorbide dinitrate in patients with and without left ventricular failure due to acute myocardial infarction

1977 • 91 citations

Myocardial Oxygen Consumption in Acute Experimental Cardiac Depression

1967 • 90 citations

Hydralazine in the management of left ventricular failure

1979 • 90 citations

Oral Hydralazine in Chronic Heart Failure: Sustained Beneficial Hemodynamic Effects

1980 • 90 citations

Myocardial prostaglandin E release by nitroglycerin and modification by indomethacin

1980 • 88 citations

Isosorbide dinitrate for the relief of severe heart failure after myocardial infarction

1976 • 87 citations

Hemodynamic effects of noninvasive systolic unloading (nitroprusside) and diastolic augmentation (external counterpulsation) in patients with acute myocardial infarction

1974 • 87 citations

Direct and reflex cardiostimulating effects of hydralazine

1977 • 87 citations

The Role of Anaerobic Metabolism in the Performance of Mild Muscular Work. I. Relationship to Oxygen Consumption and Cardiac Output, and the Effect of Congestive Heart Failure1

1958 • 86 citations

REDUCTION OF PRESSOR EFFECTS OF ANGIOTENSIN I IN MAN BY SYNTHETIC NONAPEPTIDE (B.P.P.9a OR SQ 20,881) WHICH INHIBITS CONVERTING ENZYME

1973 • 85 citations

Enhanced left ventricular performance with phentolamine in acute myocardial infarction

1974 • 85 citations

Angiotensin II: Important Role in the Maintenance of Arterial Blood Pressure

1973 • 83 citations

Effect of isosorbide dinitrate on response to submaximal and maximal exercise in patients with congestive heart failure

1979 • 81 citations

Reflex suppression of renin secretion during distention of cardiopulmonary receptors in dogs.

1976 • 81 citations

Metabolic assessment of exercise in chronic heart failure patients treated with short-term vasodilators.

1980 • 80 citations

Renin-Angiotensin System Inhibition in Conscious Sodium-Depleted Dogs

1978 • 80 citations

The Effect of Digoxin in the Splanchnic Circulation in Ventricular Failure

1965 • 80 citations

Inhibition of angiotensin converting enzyme by SQ 14,225 in conscious rabbits

1977 • 79 citations

Improved exercise ejection fraction with long-term prazosin therapy in patients with heart failure

1980 • 79 citations

Relationship between glutathione-dependent dentration and the vasodilator effectiveness of organic nitrates.

1969 • 75 citations

Aldosterone and its Regulation during Diuresis in Patients with Gross Congestive Heart Failure

1974 • 75 citations

Influence of short-term oral hydralazine therapy on exercise hemodynamics in patients with severe chronic heart failure

1979 • 74 citations

Results of long-term vasodilator therapy in patients with refractory congestive heart failure.

1981 • 74 citations

Reduction of S-T segment elevation with infusion of nitroprusside in patients with acute myocardial infarction

1976 • 73 citations

Mechanism for improved cardiac performance with arteriolar dilators in aortic insufficiency.

1981 • 72 citations

Comparison of Nitroglycerin-, Nitroprusside-, and Phentolamine-Induced Changes in Coronary Collateral Function in Dogs

1977 • 71 citations

Congestive heart failure in normotensive man. Haemodynamics, renin, and angiotensin II blockade.

1978 • 70 citations

Ventricular function and coronary hemodynamics after intravenous nitroglycerin in coronary artery disease

1978 • 69 citations

Vasodilator therapy in acute myocardial infarction.

1974 • 68 citations

Renin, aldosterone and cardiac decompensation: Studies with an oral converting enzyme inhibitor in heart failure

1979 • 68 citations

Renal effects of nitroprusside and hydralazine in patients with congestive heart failure.

1980 • 68 citations

Clinical pharmacology and therapeutic application of prazosin in acute and chronic refractory congestive heart failure

1978 • 67 citations

Effects of Experimentally Produced Heart Failure on the Peripheral Vascular Response to Severe Exercise in Conscious Dogs

1972 • 67 citations

Effect of phentolamine on noradrenaline uptake and release

1971 • 67 citations

The response of normal retinal blood vessels to angiotensin and noradrenaline

1963 • 67 citations

Effects of sodium, angiotensin, and steroids on vascular reactivity in man.

1974 • 67 citations

Cardiac Response to Increased Aortic Pressure Changes in Output and Left Ventricular Pressure Pattern at Various Levels of Inotropy

1969 • 66 citations

Comparative responses to dobutamine and nitroprusside in patients with chronic low output cardiac failure.

1977 • 66 citations

The oxygen supply of the human heart∗

1962 • 66 citations

Sodium Nitroprusside: A Review of Its Clinical Effectiveness as a Hypotensive Agent

1974 • 65 citations

Hydralazine and isosorbide dinitrate: comparative central and regional hemodynamic effects when administered alone or in combination.

1981 • 65 citations

Effect of nitroglycerin on total and regional coronary blood flow in the normal and ischaemic canine myocardium

1971 • 64 citations

Brief Reviews : Agents Which Block the Action of the Renin-Angiotensin System

1974 • 64 citations

Ineffectiveness of sublingual nitroglycerin in acute left ventricular failure in the presence of massive peripheral edema

1980 • 64 citations

Plasma Renin in Chronic Experimental Heart Failure and during Renal Sodium "Escape" from Mineralocorticoids

1968 • 64 citations

Cardiovascular effects of prazosin in normotensive and genetically hypertensive rats

1975 • 64 citations

Mechanics of isotonic left ventricular contractions

1973 • 64 citations

Control of myocardial performance early after open-heart operations by vasodilator treatment

1977 • 63 citations

Angiotensin II Inhibition

1977 • 63 citations

Use of phentolamine in acute myocardial infarction

1974 • 62 citations

Cardioaccelerator action of angiotensin

1962 • 62 citations

CAUTION WITH REGARD TO USE OF HEXAMETHONIUM AND "APRESOLINE"

1952 • 62 citations

Effects of prazosin on forearm resistance and capacitance vessels

1977 • 62 citations

Positive inotropic effects of hydralazine in human subjects: Comparison with prazosin in the setting of congestive heart failure

1980 • 61 citations

Effects of vasodilators on pulmonary hemodynamics and gas exchange in left ventricular failure

1980 • 61 citations

Central and peripheral hemodynamic effects of angiotensin inhibition in patients with refractory congestive heart failure.

1980 • 61 citations

Determinants of stroke volume in the isolated canine heart.

1974 • 61 citations

The Effect of "Sympatholytic Drugs on the Cardiovascular Responses to Epinephrine and Norepinephrine in Man

1951 • 61 citations

Inhibition of Converting Enzyme of the Renin-Angiotensin System in Kidneys and Hindlegs of Dogs

1972 • 61 citations

Development of pharmacodynamic tolerance to prazosin in congestive heart failure

1979 • 60 citations

The Mechanics of Left Ventricular Contraction in Acute Experimental Cardiac Failure*

1967 • 60 citations

The Pressure-Volume Responses of Human Forearm Veins During Epinephrine and Norepinephrine Infusions12

1957 • 60 citations

Central cardiovascular effects of SQ 14,225, an angiotensin-converting enzyme inhibitor in chloralose-anesthetized cats

1977 • 59 citations

Combination Vasodilator Therapy for Severe Chronic Congestive Heart Failure

1976 • 58 citations

Direct and reflex effects of nitroglycerin on coronary and left ventricular dynamics in conscious dogs

1972 • 58 citations

Increased Plasma Norepinephrine Levels During Prazosin Therapy for Severe Congestive Heart Failure

1980 • 58 citations

Mechanisms of beneficial effects of vasodilators and inotropic stimulation in the experimental failing ischemic heart

1978 • 57 citations

Effect of nitroprusside on smooth muscle and adrenergic nerve terminals in isolated blood vessels.

1976 • 56 citations

FINE STRUCTURAL CHANGES IN HEART MUSCLE IN RELATION TO THE LENGTH-TENSION CURVE

1963 • 56 citations

Comparative hemodynamic effects of intravenous nitroprusside and oral prazosin in refractory heart failure

1978 • 55 citations

Hemodynamic, Ventilatory and Blood Gas Changes during Infusion of Sodium Nitroferricyanide (Nitroprusside)

1977 • 55 citations

Acute and long-term effects of vasodilator therapy on resting and exercise hemodynamics and exercise tolerance.

1981 • 55 citations

THE MECHANISM OF THE INCREASED VENOUS PRESSURE WITH EXERCISE IN CONGESTIVE HEART FAILURE*†

1962 • 54 citations

BLOOD-GAS CHANGES DURING INDUCED HYPOTENSION WITH SODIUM NITROPRUSSIDE

1975 • 54 citations

Studies on hydralazine

1976 • 53 citations

Radioautographic Localization of Hydralazine-1-C14 in Arterial Walls.

1966 • 53 citations

Evaluation of sympathetic reflex effects on the inotropic action of nitroglycerin, quinidine, papaverine, aminophylline and isoproterenol.

1958 • 53 citations

Nitrate therapy of heart failure in valvular heart disease

1978 • 53 citations

Relation of sarcomere length and muscle length in resting myocardium

1970 • 52 citations

THE CIRCULATORY EFFECTS OF PHENTOLAMINE IN MAN WITH PARTICULAR RESPECT TO CHANGES IN FOREARM BLOOD FLOW.

1965 • 52 citations

Role of the venous system in circulatory control.

1978 • 51 citations

Aldosterone and the Edema of Congestive Heart Failure

1964 • 51 citations

Effectiveness of long-term vasodilator administration in the treatment of chronic left ventricular failure

1982 • 50 citations

Phentolamine for vasodilator therapy in left ventricular failure complicating acute myocardial infarction. Haemodynamic study.

1975 • 49 citations

Variations of Left Ventricular End-Diastolic Pressure, Volume, and Ejection Fraction with Changes in Outflow Resistance in Anesthetized Intact Dogs

1968 • 49 citations

Action of Angiotensin and Analogues on the Heart

1974 • 49 citations

Myocardial and haemodynamic effects of phentolamine

1971 • 48 citations

HEMODYNAMIC EFFECTS OF 1-HYDRAZINOPHTHALAZINE IN PATIENTS WITH ARTERIAL HYPERTENSION 1

1955 • 48 citations

Cardiovascular Dynamics, Blood Volumes, Renal Functions and Electrolyte Excretions in the Same Patients during Congestive Heart Failure and after Recovery of Cardiac Compensation

1953 • 47 citations

Aortic input impedance in man: acute response to vasodilator drugs.

1981 • 47 citations

The effect of sodium nitroprusside on the uptake and efflux of 45Ca from rabbit and rat vessels

1977 • 46 citations

Influence of aortic pressure-induced homeometric autoregulation on myocardial performance

1968 • 46 citations

Vascular responses after alpha adrenergic receptor blockade

1968 • 46 citations

Mechanisms of Contraction of the Normal and Failing Heart

1977 • 46 citations

The relationship of the renal vascular activity of angiotensin II to the autonomic nervous system.

1965 • 45 citations

Effects of the oral converting enzyme inhibitor, SQ 14225, in a model of low cardiac output in dogs.

1979 • 45 citations

THE EFFECTS OF SODIUM NITROPRUSSIDE ON MYOCARDIAL CONTRACTILITY AND HAEMODYNAMICS

1974 • 45 citations

Effects of continuous administration of angiotensin II on ventricular performance

1963 • 45 citations

Comparison of haemodynamic effects of phentolamine, sodium nitroprusside, and glyceryl trinitrate in acute myocardial infarction.

1977 • 45 citations

Comparative hemodynamic effects of converting enzyme inhibitor and sodium nitroprusside in severe heart failure

1980 • 44 citations

Hemodynamic Response of Oral Long-Acting Nitrates: Evidence of Gastrointestinal Absorption

1972 • 44 citations

Effect of Angiotensin II on the Intact Forearm Veins of Man

1963 • 43 citations

Circulatory Control via Vagal Afferents

1972 • 43 citations

Mechanism for improved cardiac performance with arteriolar dilators in aortic insufficiency.

1981 • 43 citations

Hemodynamics of Angiotensin in Man

1962 • 43 citations

Role of vasoconstrictor mechanisms in the control of left ventricular performance of the normal and damaged heart

1979 • 43 citations

Peripheral Venous and Arteriolar Responses to Infusions of Angiotensin in Normal and Hypertensive Subjects

1961 • 42 citations

Hemodynamic effects of intravenous phentolamine in low output cardiac failu;e. Dose-response relationships.

1978 • 42 citations

Sustained haemodynamic action of nitroglycerin ointment.

1976 • 41 citations

Effects of sodium nitroprusside and nitroglycerin on tension prolongation of cat papillary muscle during recovery from hypoxia.

1976 • 40 citations

Acute coronary occlusion: Prolonged increase in collateral flow following brief administration of nitroglycerin and methoxamine

1977 • 40 citations

The Kidney in Systemic Disease

1981 • 40 citations

Prolonged salutary effects of isosorbide dinitrate and nitroglycerin ointment on regional left ventricular function

1977 • 39 citations

Influence of congestive heart failure on prazosin kinetics

1979 • 39 citations

Beneficial hemodynamic response to chronic prazosin therapy in congestive heart failure

1981 • 38 citations

THE EFFECTS OF SYNTHETIC ANGIOTENSIN AND NORADRENALINE ON BLOOD PRESSURE AND RENAL FUNCTION

1961 • 38 citations

Effect of acute ischemia, nitroglycerin and nitroprusside on regional myocardial thickening, stress and perfusion. Experimental echocardiographic studies.

1979 • 38 citations

Oral vasodilator therapy for chronic heart failure: A plea for caution

1978 • 38 citations

Depressed inotropic state and reduced myocardial oxygen consumption in the human heart

1973 • 38 citations

A Hypoxic Pulmonary Vasoconstrictor Response in Dogs during and after Infusion of Sodium Nitroprusside

1979 • 37 citations

Radionuclide angiography: Noninvasive assessment of hemodynamic changes after administration of nitroglycerin

1979 • 36 citations

Postural hypotension and tachycardia during hydralazine--isosorbide dinitrate therapy for chronic heart failure.

1981 • 36 citations

Influence of Experimental Edema on Metabolically Determined Blood Flow

1974 • 36 citations

Provocation of myocardial ischemic events during initiation of vasodilator therapy for severe chronic heart failure

1981 • 36 citations

The clinical results of oral and parenteral administration of 2-(N'p-tolyl-N′-m-hydroxyphenylami-nomethyl) imidazoline hydrochloride (regitine) in the treatment of hypertension and an evaluation of the cerebral hemodynamic effects

1953 • 36 citations

Comparative Effects of Intra‐arterially Administered Hydralazine and Sodium Nitrite on Blood Flow and Volume of Forearm ¹

1963 • 36 citations

Beta adrenergic mediated inotropic and chronotropic actions of phentolamine

1970 • 36 citations

Comparative Effects of Intra‐arterially Administered Isoprenaline and Sodium Nitrite on Blood Flow and Volume of the Forearm

1967 • 35 citations

Inhibition of Angiotensin I-Initiated Hemodynamic Changes in Anesthetized Dogs by a Synthetic Nonapeptide

1972 • 35 citations

The dynamics of mitral insufficiency

1954 • 34 citations

Afterload reduction with phentolamine in patients with acute pulmonary edema

1977 • 34 citations

Biotransformation of Organic Nitrates

1975 • 34 citations

The renin-angiotensin-aldosterone system in rabbits with congestive heart failure produced by aortic constriction.

1977 • 34 citations

Some Contributions to the Pharmacology of Synthetic Angiotensin

1962 • 33 citations

Acute and long-term effects of vasodilator therapy on resting and exercise hemodynamics and exercise tolerance.

1981 • 33 citations

TECHNIQUES OF VASCULAR CONTROL FOR DELIBERATE HYPOTENSION DURING ANAESTHESIA

1975 • 33 citations

Rest and exercise hemodynamic effects of oral hydralazine in patients with coronary artery disease and left ventricular dysfunction.

1980 • 32 citations

Studies on the inotropic mechanism of phentolamine

1970 • 32 citations

Altered prazosin pharmacokinetics in congestive heart failure

1980 • 32 citations

Response of the left ventricle to nitroglycerin in patients with and without mitral regurgitation.

1974 • 32 citations

Mechanisms of cardioaccelerator action of angiotensin

1965 • 31 citations

Arterial hypertension elicited by prolonged intra-vertebral infusion of angiotensin II in conscious dog

1971 • 31 citations

Phentolamine and Beta‐Adrenergic Receptors

1971 • 31 citations

Circulatory Control via Vagal Afferents VI. The bleeding bradycardia in the rat, its elicitation and relation to the release of vasopressin

1973 • 30 citations

Nitroglycerin-induced improvement in exercise tolerance and hemodynamics in patients with chronic rheumatic heart valve disease

1978 • 29 citations

Hemodynamic evaluation of hydralazine dosage in refractory heart failure

1980 • 29 citations

Arterial Angiotensin Levels in Edematous Patients.

1963 • 29 citations

The Contribution of Local Factors to the Elevated Venous Tone of Congestive Heart Failure

1974 • 29 citations

The effects of intracoronary nitroglycerin on left ventricular systolic and diastolic function in man.

1980 • 28 citations

Myocardial inactivity of therapeutic concentrations of hydralazine and diazoxide

1974 • 28 citations

Hemodynamic and Metabolic Responses to Upright Exercise in Patients with Congestive Heart Failure

1979 • 28 citations

Renin activity and norepinephrine, cation, and water contents of cardiovascular tissue of dogs with congestive heart failure and ascites

1970 • 28 citations

THE EFFECTS OF 1-HYDRAZINOPHTHALAZINE ON CEREBRAL BLOOD FLOW, VASCULAR RESISTANCE, OXYGEN UPTAKE AND JUGULAR OXYGEN TENSION IN HYPERTENSIVE SUBJECTS 1

1953 • 28 citations

Sustained effectiveness of chronic prazosin therapy in severe chronic congestive heart failure

1981 • 28 citations

Beneficial effects of afterload reduction therapy in patients with congestive heart failure and moderate aortic stenosis.

1980 • 27 citations

Differences in hemodynamic effects of nitroprusside and prazosin in severe chronic congestive heart failure

1979 • 27 citations

Cardiac adrenergic activity in experimental heart failure assessed with beta receptor blockade

1969 • 27 citations

Improvement in exercise haemodynamics by isosorbide dinitrate in patients with severe congestive cardiac failure secondary to ischaemic heart disease.

1978 • 27 citations

The effects of the beta-blocker atenolol and nitroglycerin on left ventricular function and geometry in man.

1979 • 26 citations

Haemodynamic effects of prazosin.

1976 • 26 citations

Cardiovascular and Renal Responses to the Combination of Hexamethonium and 1-Hydrazinophthalazine (Apresoline®) in Hypertensive Subjects1

1955 • 26 citations

Further Studies of the Effects on Myocardial Energy Utilization Elicited by Nitroglycerin

1960 • 25 citations

Absence of direct chronotropic action of angiotensin infused into the sinus node artery

1965 • 25 citations

Pharmacological Properties of Hydrallazine, Dihydrallazine and Some Related Compounds

1957 • 24 citations

Arterial pressure as a determinant of left ventricular filling pressure after acute myocardial infarction

1974 • 24 citations

Role of endocrine factors in chronic congestive heart failure, with emphasis on catecholamines.

1980 • 24 citations

Hemodynamic effects of topical, oral and sublingual nitroglycerin in left ventricular failure

1977 • 22 citations

Cardiopulmonary Effects of Glyceryl Trinitrate and Isosorbide Dinitrate

1968 • 22 citations

Mode of action of hydralazine on guinea pig atria.

1967 • 21 citations

PLASMA RENIN IN CONGESTIVE HEART FAILURE IN MAN

1970 • 21 citations

Circulatory response to vasodilator therapy in congestive cardiomyopathy.

1976 • 21 citations

Evidence for a positive inotropic effect of nitroglycerol on isolated human ventricular myocardium

1971 • 21 citations

Changes in the oxygen content of axillary venous blood during leg exercise in patients with rheumatic heart disease.

1955 • 21 citations

Postural hypotension and tachycardia during hydralazine--isosorbide dinitrate therapy for chronic heart failure.

1981 • 20 citations

Comparison of haemodynamic effects of oral hydralazine and prazosin hydrochloride in patients with chronic congestive heart failure.

1979 • 19 citations

STUDIES WITH PRAZOSIN—A NEW EFFECTIVE HYPOTENSIVE AGENT. II

1977 • 19 citations

Haemodynamic effects of hydralazine at rest and during exercise in patients with chronic heart failure.

1980 • 19 citations

Isosorbide Dinitrate-Induced Improvement in Left Ventricular Ejection Fraction during Exercise in Coronary Arterial Disease

1978 • 19 citations

High renin in heart failure: a manifestation of hyponatremia.

1979 • 19 citations

Vascular responses after alpha adrenergic receptor blockade

1968 • 19 citations

Effects of isosorbide dinitrate and hydralazine on regional metabolic responses to arm exercise in patients with heart failure

1981 • 19 citations

Haemodynamic effects of hydrallazine and of hydrallazine plus glyceryl trinitrate paste in heart failure.

1978 • 19 citations

Haemodynamic effects of phentolamine in chronic obstructive pulmonary disease.

1971 • 18 citations

Effect of sodium nitroprusside on myocardial performance and venous tone

1975 • 17 citations

Prazosin: Preliminary Clinical and Pharmacological Observations

1974 • 17 citations

Contrasting acute and chronic effects of nitrates on exercise capacity in heart failure

1979 • 17 citations

Reversal of premature mitral valve closure by nitroprusside infusion in severe aortic insufficiency: Beat to beat pressure-flow and echocardiographic relationships

1976 • 17 citations

Cardiac effects of angiotensin injections into perfused right coronary artery

1967 • 17 citations

Dose dependence of the hemodynamic responses to nitrate therapy in patients with refractory congestive heart failure

1979 • 16 citations

Effects of intracoronary and intravenous nitroglycerin on coronary collateral function.

1976 • 16 citations

Hemodynamic Improvement following a Single Dose of Oral Phentolamine

1979 • 15 citations

Vascular effects of angiotensin and norepinephrine in the dog, cat, and monkey

1965 • 15 citations

The renin-angiotensin-aldosterone system and catecholamines in chronic congestive heart failure. Effect of angiotensin I converting enzyme inhibitor SQ 14225 (captopril).

1980 • 15 citations

Pattern of differential vasoconstriction in response to acute and chronic low-output states in the conscious dog

1974 • 14 citations

Cardio-dynamic effects of mitral commissurotomy.

1950 • 14 citations

Central and Renal Circulation, Renin and Aldosterone in Plasma during Prazosin Treatment in Essential Hypertension

1979 • 14 citations

Mechanism of the hypotensive effect of prazosin.

1976 • 14 citations

Relationship of Cardiorenal Function to Renin-Aldosterone System in Patients with Valvular Heart Disease

1971 • 13 citations

Variable hemodynamic response to oral hydralazine in patients with refractory congestive heart failure*

1980 • 13 citations

Comparative haemodynamic and peripheral vasodilator effects of oral and chewable isosorbide dinitrate in patients with refractory congestive cardiac failure.

1979 • 13 citations

Lowered Aortic Impedance as Therapy for Severe Mitral Regurgitation

1974 • 13 citations

The effect of isosorbide dinitrate on left ventricular size, wall stress and left ventricular function in chronic refractory heart failure

1978 • 13 citations

Dose dependent reduction in right and left ventricular filling pressures with hydralazine

1978 • 13 citations

Some cardiovascular actions of sodium nitroprusside in the dog.

1973 • 13 citations

THE EFFECT OF ADRENERGIC BLOCKADE ON THE CIRCULATORY RESPONSE TO EXERCISE IN MAN.

1965 • 13 citations

Haemodynamic effects of sodium nitroprusside in 21 subjects with congestive heart failure.

1979 • 12 citations

Sustained benefits of oral pentaerythritol tetranitrate on ventricular function in chronic congestive heart failure

1980 • 12 citations

Prolonged hemodynamic effects (12 hours) of orally administered sustained-release nitroglycerin

1979 • 12 citations

Use of oral prazosin hydrochloride in congestive failure following acute myocardial infarction

1979 • 12 citations

Contrasting effects of nitroprusside and phentolamine in experimental myocardial infarction

1977 • 12 citations

Responses of the Human Upper Extremity Vascular Bed to Exercise, Cold, Levarterenol, Angiotensin, Hypertension, Heart Failure, and Respiratory Tract Infection with Fever *

1964 • 12 citations

Oral Therapy with Phentolamine in Chronic Congestive Heart Failure

1979 • 12 citations

Effect of Progressive Pressure Reduction with Nitroprusside on Acute Myocardial Infarction in Humans

1981 • 12 citations

Coronary flow changes and cardiac adrenergic blockade during nitroglycerin infusions

1970 • 12 citations

Natriuretic Effect of Angiotensin in Dogs Revealed after Administration of Reserpine and Guanethidine

1967 • 11 citations

Oral captopril in ambulatory management of severe congestive heart failure: Sustained beneficial effects on ventricular function with 6 months therapy shown by cardiac catheterization, nuclear scintigraphy, echography, treadmill exercise and symptomatology

1980 • 11 citations

Hemodynamic Effects of Phentolamine In Cor Pulmonale

1972 • 11 citations

Comparison of haemodynamic effects of oral prazosin, oral hydralazine, and intravenous nitroprusside in same patients with chronic heart failure.

1979 • 11 citations

Treatment of Acute Aortic Insufficiency with Sodium Nitroferricyanide

1977 • 11 citations

Alpha-adrenergic blocking activity of prazosin

1979 • 10 citations

Effect of vasodilator drugs on exercise performance in cardiac failure. Comparison of hydralazine and prazosin.

1980 • 10 citations

Direct inotropic effects of the afterload reducing agents, hydralazine and prazosin, evaluated in isolated cat papillary muscle preparation

1978 • 10 citations

Vasodilator treatment with isosorbide dinitrate and hydralazine in chronic heart failure.

1981 • 10 citations

Hemodynamic effects of nitroglycerin VS pure preload reduction: Masked arteriolar dilatory effect

1978 • 9 citations

Effect of phentolamine on peripheral venous distensibility in congestive heart failure

1974 • 9 citations

Increased forearm venous compliance during exercise with nitroglycerin.

1974 • 9 citations

Adrenergic Control of the Peripheral Circulation in Cardiomyopathic Hamsters with Heart Failure

1973 • 9 citations

Regulation of cardiac output after administration of isoproterenol and ouabain: interactions of systolic impedance and contractility

1972 • 8 citations

Phentolamine

1970 • 8 citations

The role of the sympathetic nervous system in the pathogenesis of halothane-induced malignant hyperthermia in the pietrain pig [proceedings].

1978 • 8 citations

Effects of Prazosin on Plasma Renin Activity and Blood Pressure

1979 • 8 citations

Hemodynamics, compartments and the renin-aldosterone system in chronic heart failure.

1975 • 8 citations

Study of left ventricular pressure-volume relations during nitroprusside infusion in human subjects without coronary artery disease.

1979 • 7 citations

Relationship between the hypotensive and alpha-adrenoceptor blocking actions of prazosin.

1979 • 7 citations

Renin and Aldosterone in the Cardiomyopathic Hamster in Congestive Heart Failure

1977 • 7 citations

The cause of hypoxemia induced by nitroglycerin

1979 • 7 citations

Relationship between the hypotensive and alpha-adrenoceptor blocking actions of prazosin.

1979 • 7 citations

Phenotlamine. Use in congestive heart failure.

1970 • 6 citations

Isosorbide dinitrate in acute and chronic heart failure

1979 • 6 citations

Treatment of chronic heart failure with slow release phentolamine

1978 • 6 citations

Direct effects of prazosin on the canine sinus node

1981 • 6 citations

Comparative hemodynamic effects of low dose and high dose nitroprusside in patients with refractory congestive heart failure

1979 • 5 citations

Effects of nitroglycerin infusion on the hemodynamic response to exercise in rats in heart failure

1979 • 5 citations

Controlled study of intravenous nitroglycerin treatment for two days in patients with recent myocardial infarction

1980 • 5 citations

Can hydralazine therapy for severe, chronic, heart failure be safely and effectively initiated outside the hospital?

1980 • 5 citations

Aldosterone and renin-angiotensin responses to stimuli in patients with treated congestive heart failure.

1976 • 5 citations

Influence of Angiotensin on the Hemodynamic Response to Exercise in Normotensive Subjects

1968 • 4 citations

Comparison of the cardiovascular effects of phentolamine, sodium nitroprusside and nitroglycerin in anaesthetized cats (Comparison of vasodilators)

1977 • 4 citations

Effects of oral hydralazine on rest and exercise hemodynamics in patients with aortic or mitral regurgitation and left ventricular dysfunction

1981 • 4 citations

Hemodynamic Effects of Phentolamine in Mitral Stenosis and Congestive Cardiomyopathy

1979 • 4 citations

Mechanism of transient prazosin hemodynamic “tachyphyl-axis” in heart failure: Acute, subacute and late serial evaluation of alpha receptor responses with phenylephrine by cardiac catheterization during prolonged oral prazosin therapy

1981 • 3 citations

Sodium Nitroprusside Therapy in Congestive Cardiomyopathy—Variability in Hemodynamic Response

1978 • 3 citations

Hemodynamic Effects of Phentolamine in Valvular Abnormalities

1978 • 3 citations

Relationships of acute captopril effect in heart failure on renin and sympathetic mechanisms

1980 • 3 citations

Relationship of myocardial prostaglandin E to hemodynamic effects of isosorbide dinitrate

1979 • 3 citations

Effect of nitroprusside on end-diastolic pressure-diameter relations of the human left ventricle after pericardiotomy

1980 • 3 citations

Effects of systemic vasodilators on pulmonary venous tone

1979 • 2 citations

Hydralazine effects on hemodynamics, cardiac contractile function and myocardial energetics in isolated myocardium

1980 • 2 citations

Hydralazine improves rest and exercise cardiac performance in mitral regurgitation

1980 • 2 citations

Oral prazosin in cardiac failure due to acute myocardial infarction: Comparable hemodynamic effects to nitroprusside

1979 • 2 citations

Preservation of blood flow to kidney and gut by intravenous nitroglycerin during exercise in rats with heart failure

1979 • 1 citations

Plasma norepinephrine determines hypotensive responsiveness to nitroprusside in hypertension

1980 • 1 citations

Nitroglycerin effects in valvular aortic stenosis

1979 • 1 citations

Angiotensin II blockade in congestive heart failure.

1978 • 1 citations

Deleted Work

1955 • 0 citations