The Kidney in Systemic Disease

Inhibition of Prostaglandin Synthesis as a Mechanism of Action for Aspirin-like Drugs

1971 • 8,596 citations

The Glycosylation of Hemoglobin: Relevance to Diabetes Mellitus

1978 • 873 citations

Glomerular hemodynamics in experimental diabetes mellitus

1981 • 785 citations

Development and Clinical Application of a New Method for the Radioimmunoassay of Arginine Vasopressin in Human Plasma

1973 • 773 citations

Evidence for the Secretion of an Osteoclast Stimulating Factor in Myeloma

1974 • 681 citations

Control of renin release.

1967 • 526 citations

Function of the thick ascending limb of Henle's loop

1973 • 503 citations

Effect of vasopressin and cyclic AMP on permeability of isolated collecting tubules

1966 • 448 citations

Angiotensin II effects upon the glomerular microcirculation and ultrafiltration coefficient of the rat.

1976 • 414 citations

Sodium Chloride and Water Transport in the Medullary Thick Ascending Limb of Henle. EVIDENCE FOR ACTIVE CHLORIDE TRANSPORT

1973 • 410 citations

Contraction of Cultured Rat Glomerular Cells of Apparent Mesangial Origin after Stimulation with Angiotensin II and Arginine Vasopressin

1980 • 400 citations

The Dynamics of Glomerular Ultrafiltration in the Rat

1971 • 395 citations

Permselectivity of the glomerular capillary wall: III. Restricted transport of polyanions

1975 • 383 citations

The Mechanism of the Calorigenic Action of Thyroid Hormone

1971 • 372 citations

Production of Hypertonic Urine in the Absence of Pituitary Antidiuretic Hormone1

1957 • 360 citations

THE NATURE OF BENCE-JONES PROTEINS

1962 • 353 citations

Prostaglandin biosynthesis by rabbit renomedullary interstitial cells in tissue culture. Stimulation by angiotensin II, bradykinin, and arginine vasopressin.

1977 • 351 citations

Reduced Erythrocyte Deformability in Diabetes

1978 • 349 citations

Effects of norepinephrine and angiotensin II on the determinants of glomerular ultrafiltration and proximal tubule fluid reabsorption in the rat.

1975 • 336 citations

Bartter's syndrome: A disorder characterized by high urinary prostaglandins and a dependence of hyperreninemia on prostaglandin synthesis

1976 • 321 citations

Effect of Prostaglandin (PGEI) on the Permeability Response of Toad Bladder to Vasopressin, Theophylline and Adenosine 3′,5′-monophosphate

1965 • 298 citations

The renal handling of low molecular weight proteins

1972 • 275 citations

Patterns of Amyloidosis and Their Association with Plasma-Cell Dyscrasia, Monoclonal Immunoglobulins and Bence-Jones Proteins

1974 • 263 citations

Glomerular size and structure in diabetes mellitus. II. Late abnormalities

1977 • 262 citations

The Regulation of Extracellular Fluid Volume

1970 • 257 citations

The Role of Sodium-Potassium—Activated Adenosine Triphosphatase in the Reabsorption of Sodium by the Kidney*

1967 • 247 citations

Dynamics of glomerular ultrafiltration in the rat. II. Plasma-flow dependence of GFR

1972 • 246 citations

Fanconi syndrome in adults

1975 • 228 citations

Evidence for a prostaglandin-independent defect in chloride reabsorption in the loop of henle as a proximal cause of Bartter's syndrome

1978 • 220 citations

Intracellular pH transients in giant barnacle muscle fibers

1977 • 219 citations

Glomerular size and structure in diabetes mellitus

1977 • 212 citations

Acute Oliguric Renal Failure Induced by Indomethacin: Possible Mechanism

1979 • 211 citations

Studies of the Rate of Regression of the Glomerular Lesions in Diabetic Rats Treated with Pancreatic Islet Transplantation

1975 • 211 citations

Diabetes and hypertensive vascular disease

1973 • 208 citations

SOME EFFECTS OF HUMAN GROWTH HORMONE ON RENAL HEMODYNAMICS AND ON TUBULAR PHOSPHATE TRANSPORT IN MAN*

1962 • 207 citations

Unmasking of thromboxane A2 synthesis by ureteral obstruction in the rabbit kidney

1977 • 201 citations

Increased Synthesis of Prostaglandin-E-like Material by Platelets from Patients with Diabetes Mellitus

1977 • 195 citations

The Effects of Goldblatt Hypertension on Development of the Glomerular Lesions of Diabetes Mellitus in the Rat

1978 • 193 citations

The kidney in potassium depletion

1958 • 183 citations

Current Status of Capillary Basement-membrane Disease in Diabetes Mellitus

1977 • 181 citations

Vascular Reactivity to Angiotensin II and to Norepinephrine in Diabetic Subjects

1976 • 179 citations

The Effect of Ca and Antidiuretic Hormone on Na Transport across Frog Skin

1963 • 174 citations

Impaired water excretion in myxedema

1971 • 174 citations

ACUTE RENAL FAILURE IN MULTIPLE MYELOMA

1975 • 169 citations

Increased Plasma Arginine Vasopressin in Clinical Adrenocortical Insufficiency and Its Inhibition By Glucosteroids*

1967 • 169 citations

The Clinical Course of Diabetic Nephropathy

1976 • 169 citations

Glomerular size and structure in diabetes mellitus

1975 • 162 citations

Modulation by prostaglandin synthesis inhibitors of the action of exogenous angiotensin II on glomerular ultrafiltration in the rat.

1978 • 162 citations

Kidney Function and Glomerular Permeability to Macromolecules in Early Juvenile Diabetes

1971 • 150 citations

EFFECTS OF REDUCED GLOMERULAR FILTRATION ON URINE CONCENTRATION IN THE PRESENCE OF ANTIDIURETIC HORMONE*

1959 • 149 citations

The adult Fanconi syndrome

1957 • 148 citations

Evidence for renal glomerular receptors for angiotensin II

1974 • 148 citations

The mode of inhibition by calcium of cell-membrane adenosine-triphosphatase activity

1966 • 148 citations

Thromboxane A2 biosynthesis in the ureter obstructed isolated perfused kidney of the rabbit.

1978 • 146 citations

Biochemical properties of human glomerular basement membrane in normal and diabetic kidneys.

1974 • 143 citations

On the role of antidiuretic hormone in the inhibition of acute water diuresis in adrenal insufficiency and the effects of gluco- and mineralocorticoids in reversing the inhibition

1970 • 141 citations

ON THE IMPAIRMENT OF RENAL CONCENTRATING ABILITY IN PROLONGED HYPERCALCEMIA AND HYPERCALCIURIA IN MAN*

1961 • 141 citations

Renal potassium wasting in renal tubular acidosis (RTA)

1971 • 140 citations

Renal Dysfunction Associated With Methoxyflurane Anesthesia

1971 • 136 citations

Nonosmolar Factors Affecting Renal Water Excretion

1975 • 131 citations

Multiple myeloma and the adult Fanconi syndrome

1957 • 128 citations

Mechanism of Reduced Glomerular Filtration Rate in Chronic Malnutrition

1980 • 128 citations

Vasopressin-stimulated prostaglandin E biosynthesis in the toad urinary bladder. Effect of water flow.

1977 • 124 citations

Plasma protein changes, blood viscosity, and diabetic microangiopathy.

1976 • 119 citations

Renin, Angiotensin, and Norepinephrine in Alloxan Diabetes

1974 • 119 citations

Disturbance of Serum Viscosity in Diabetes Mellitus

1974 • 117 citations

Role of Plasma Vasopressin in Impaired Water Excretion of Glucocorticoid Deficiency

1978 • 116 citations

Effect of Mannitol on Glomerular Ultrafiltration in the Hydropenic Rat

1974 • 115 citations

Regional vascular effects of vasopressin: plasma levels and circulatory responses

1974 • 114 citations

Renal Sodium- and Potassium-Activated Adenosine Triphosphatase and Sodium Reabsorption in the Hypothyroid Rat

1973 • 113 citations

Amyloidosis

1967 • 111 citations

The Renal Diluting and Concentrating Mechanism in Hypercalcemia

1969 • 111 citations

Renal handling of sodium and water in the hypothyroid rat

1972 • 109 citations

Mechanics of Glomerular Ultrafiltration

1977 • 108 citations

Evidence for a direct effect of parathyroid hormone on urinary acidification

1965 • 108 citations

Centrally Mediated Effects of Sodium and Angiotensin II on Arterial Blood Pressure and Fluid Balance

1972 • 105 citations

Importance of sodium intake and mineralocorticoid hormone in the impaired water excretion in adrenal insufficiency

1972 • 104 citations

Nephrotoxicity of Bence Jones proteins in the rat: Importance of protein isoelectric point

1979 • 100 citations

Antidiuretic hormone increases renal prostaglandin synthesis in vivo

1978 • 100 citations

Effects of myxedema on the renal diluting and concentrating mechanism

1971 • 99 citations

Cellular actions of vasopressin in the mammalian kidney

1976 • 98 citations

George C. Griffith lecture. The role of renin in normal and pathological cardiovascular homeostasis.

1976 • 97 citations

Mechanism of Impaired Water Excretion in the Hypothyroid Rat

1974 • 97 citations

ON THE MECHANISM OF IMPAIRMENT OF RENAL CONCENTRATING ABILITY IN HYPERCALCEMIA*

1960 • 95 citations

Evidence for glomerular actions of ADH and dibutyryl cyclic AMP in the rat

1977 • 94 citations

ADRENAL STEROID INHIBITION OF VASOPRESSIN RELEASE FROM THE NEUROHYPOPHYSIS OF NORMAL SUBJECTS AND PATIENTS WITH ADDISON'S DISEASE *

1960 • 93 citations

THE ADULT FANCONI SYNDROME

1972 • 92 citations

CHANGES IN RENAL CONCENTRATING ABILITY PRODUCED BY PARATHYROID EXTRACT*

1959 • 91 citations

Nephrogenic diabetes insipidus caused by amyloid disease

1960 • 90 citations

Studies on the Mechanism of Hyponatremia and Impaired Water Excretion in Myxedema

1962 • 88 citations

Renal accumulation of salicylate and phenacetin: possible mechanisms in the nephropathy of analgesic abuse

1968 • 87 citations

Studies of diabetic nephropathy in animals and man.

1976 • 84 citations

Renal acidosis

1972 • 83 citations

Renal actions of prostaglandins: comparison with acetylcholine and volume expansion

1972 • 83 citations

Studies on the Site of Renal Salt Loss in a Patient with Bartter's Syndrome

1973 • 82 citations

Mechanisms of Impaired Water Excretion in Adrenal and Pituitary Insufficiency. I. The Role of Altered Glomerular Filtration Rate and Solute Excretion12

1958 • 82 citations

Studies on the exaggerated natriuretic response to a saline infusion in the hypothyroid rat

1970 • 81 citations

WILSON'S DISEASE AND THE FANCONI SYNDROME

1962 • 81 citations

Experimental Bence Jones cast nephropathy.

1976 • 78 citations

Role of antidiuretic hormone in the abnormal water diuresis of anterior hypopituitarism in man

1971 • 77 citations

Relation of distal tubular NaCl delivery and glomerular hydrostatic pressure

1972 • 77 citations

Hyporeninemic Hypoaldosteronism in Diabetes Mellitus: Studies of the Autonomic Nervous System's Control of Renin Release

1979 • 76 citations

Effect of salicylate on oxidative phosphorylation and respiration of mitochondrial fragments

1965 • 76 citations

Magnitude of the renal failure problem in diabetic patients.

1974 • 75 citations

Effects of phloretin and theophylline on 3-O-methylglucose transport by intestinal epithelial cells

1978 • 74 citations

Renal complications in multiple myeloma: Pathophysiology and some aspects of clinical management

1971 • 74 citations

Effects of Volume Expansion, Purified Parathyroid Extract, and Calcium on Renal Bicarbonate Absorption in the Dog

1974 • 74 citations

Modulation of Cyclic Nucleotides in Isolated Rat Glomeruli

1978 • 72 citations

EFFECT OF EXPERIMENTAL DIABETES, FOOD DEPRIVATION AND GENETIC OBESITY ON THE SENSITIVITY OF PITHED RATS TO AUTONOMIC AGENTS

1976 • 72 citations

Glomerular Filtration Rate and Renal Plasma Flow in Normal and Diabetic Man during Elevation of Blood Sugar Levels

1971 • 70 citations

On the mechanism of renal potassium wasting in renal tubular acidosis associated with the Fanconi syndrome (type 2 RTA)

1971 • 70 citations

EXCRETION AND REABSORPTION OF SODIUM AND WATER IN THE ADRENALECTOMIZED DOG

1949 • 70 citations

Diabetic glomerulopathy following unilateral nephrectomy in the rat

1978 • 68 citations

Effects of a portacaval or peritoneovenous shunt on renin in the hepatorenal syndrome

1979 • 68 citations

Evidence for a parathyroid hormone-dependent influence of calcium on the glomerular ultrafiltration coefficient.

1978 • 68 citations

Dynamics of glomerular ultrafiltration. IX. Effects of plasma protein concentration

1977 • 66 citations

Influence of diabetes upon the inflammatory response of the rat. A pharmacological analysis

1973 • 63 citations

Effects of Parathyroid Hormone on Glomerular Ultrafiltration in the Rat

1982 • 61 citations

AMINO-ACIDURIA, HYPOPHOSPHATEMIA, AND RICKETS IN LEAD POISONING<subtitle>Study of a Case</subtitle>

1955 • 60 citations

Effect of glycine and glucagon on glomerular filtration and renal metabolic rates

1977 • 59 citations

SPECIFIC RENAL FUNCTIONS IN HYPERTHYROIDISM AND MYXEDEMA

1947 • 59 citations

POLYURIA IN HYPERPARATHYROIDISM

1957 • 59 citations

RENAL PATTERNS IN MYELOMA

1960 • 58 citations

Stimulation of adenylate cyclase in isolated rat glomeruli by prostaglandins

1978 • 55 citations

Hypercalcemic Nephropathy

1978 • 54 citations

Sodium in smooth muscle relaxation

1977 • 54 citations

Factors in the Renal Failure of Multiple Myeloma

1965 • 53 citations

Glomerular Filtration Rate and Renal Plasma Flow in Long-term Juvenile Diabetics without Proteinuria

1972 • 53 citations

RESTORATION OF WATER DIURESIS IN ADDISONIAN PATIENTS BY EXPANSION OF THE VOLUME OF EXTRACELLULAR FLUID*

1962 • 51 citations

The acute effect of insulin on renal haemodynamics and protein excretion in diabetics

1978 • 50 citations

Angiotensin II binding to renal glomeruli from sodium-loaded and sodium-depleted rats

1976 • 50 citations

HYPOKALEMIC NEPHROPATHY IN RAT AND MAN: A LIGHT AND ELECTRON MICROSCOPIC STUDY.

1964 • 50 citations

Stimulation of prostaglandin biosynthesis in the renal papilla by hypertonic mediums

1978 • 48 citations

Hyperkalemia and Renal Tubular Acidosis Due to Renal Amyloidosis

1969 • 48 citations

Ionic milieu and control of K permeability in the parotid gland

1978 • 48 citations

Effect of parathormone and cyclic adenosine monophosphate on renal bicarbonate reabsorption

1974 • 45 citations

Adult Fanconi syndrome with monoclonal abnormality of immunoglobulin light chain

1967 • 44 citations

Hormonal Function and the Kidney.

1980 • 43 citations

RENAL CLEARANCE IN PATIENTS WITH MYXEDEMA

1955 • 43 citations

Evidence for parathyroid hormone sensitive adenylate cyclase in rat glomeruli

1974 • 42 citations

Unilateral renal disease in the rat. II. Glomerular mesangial uptake of colloidal carbon in unilateral aminonucleoside nephrosis and nephrotoxic serum nephritis.

1976 • 42 citations

Renal Concentrating Mechanism: Possible Role for Sodium-Potassium Activated Adenosine Triphosphatase

1969 • 40 citations

Hormone-sensitive adenylate-cyclase in isolated rabbit glomeruli

1974 • 39 citations

The Effect of Bence Jones Protein on the <i>in vitro</i> Function of Rabbit Renal Cortex

1968 • 39 citations

Parathormone-induced renal bicarbonate wastage in intestinal malabsorption and in chronic renal failure

1970 • 39 citations

A CORTISONE-RESISTANT ABNORMALITY IN THE DIURETIC RESPONSE TO INGESTED WATER IN PRIMARY MYXEDEMA

1954 • 38 citations

Effect of hypercalcemia on renal tubular sodium handling in the rat

1971 • 37 citations

Effects on Rat Kidney Slice Function In Vitro of Proteins from the Urines of Patients with Myelomatosis and Nephrosis

1974 • 36 citations

Magnitude of Metabolic Acidosis in Primary Hyperparathyroidism

1974 • 35 citations

Inhibitory effects of aspirin and indomethacin on the biosynthesis of PGE2 and PGF2α

1974 • 34 citations

The Renal Concentrating Capacity in Albino Rats after Long‐term Consumption of Phenacetin, NAPA (N‐acetyl‐p‐aminophenol) and Acetylsalicylic Acid

1964 • 32 citations

Binding of 125I-insulin to the isolated glomeruli of rat kidney.

1979 • 31 citations

Plasma Vasopressin Concentration in the Adrenally Insufficient Dog

1970 • 30 citations

Renal Amyloidosis, Nephrotic Syndrome, and Impaired Renal Tubular Reabsorption of Bicarbonate

1968 • 30 citations

Effect of indomethacin and adrenocorticotrophic hormone on renal function in man: An experimental model of inappropriate antidiuresis

1979 • 29 citations

EFFECT OF STEROIDS ON WATER DIURESIS AND VASOPRESSIN SENSITIVITY*

1961 • 28 citations

Thyroidal Regulation of Renal Energy Metabolism and (Na+ + K+)-Activated Adenosine Triphosphatase Activity

1975 • 28 citations

INHIBITION OF ACTIVE-TRANSPORT SODIUM-POTASSIUM-A.T.P.ase BY MYELOMA PROTEIN

1978 • 26 citations

The effect of glucose on the synthesis of prostaglandins by the renal papilla of the rat in vitro

1979 • 26 citations

Hormonal influences on glomerular filtration

1980 • 25 citations

Renal removal of low molecular weight proteins in myeloma and renal transplant patients.

1974 • 24 citations

IMPAIRED WATER EXCRETION CAPACITY IN PRIMARY MYXOEDEMA IMPROVED BY CORTICOSTEROIDS, CORTICOTROPHIN AND THYROID SUBSTITUTION

1960 • 24 citations

Detection, Significance and Treatment of Paraprotein in Patients Presenting with ‘Idiopathic’ Proteinuria without Myeloma

1978 • 24 citations

Renin Secretion during Mannitol Diuresis and Ureteral Occlusion

1968 • 24 citations

Interstitial Fibrosis and Chronic Renal Failure Following Methoxyflurane Anesthesia

1973 • 22 citations

The Relationship of "Chronic Pyelonephritis" to Chronic Potassium Deficiency

1963 • 22 citations

Urine Dilution and Concentration After Digoxin Infusion into the Renal Artery of Dogs

1970 • 20 citations

Characteristics of Renal Handling of Human Immunoglobulin Light Chain by the Perfused Rat Kidney

1979 • 20 citations

The Kidney in Systemic Disease.

1976 • 20 citations

THE DIURETIC RESPONSE TO ADMINISTERED WATER IN PATIENTS WITH PRIMARY MYXEDEMA

1960 • 17 citations

The influence of rouleaux on the resistance to flow through capillary channels at various shear rates

1975 • 17 citations

Renal Response to Sodium Restriction in Myxedema

1974 • 10 citations

The Immunohistopathology of Glomerular Antigens: III. Increased Mesangial Actomyosin in Experimental Diabetes in the Rat

1978 • 9 citations

Mechanism of decrease in plasma renin activity during volume expansion

1976 • 9 citations

The Nature of Genius

1956 • 6 citations

Reduction in cardiovascular and metabolic responses to phenylephrine in acutely pancreatectomized dogs

1966 • 3 citations

Deleted Work

1955 • 0 citations