Reduced expression of the A? subunit of protein phosphatase 2A in human gliomas in the absence of mutations in the A? and A? subunit genes
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References (35)
Protein serine/threonine phosphatases: structure, regulation, and functions in cell growth
1993 • 662 citations
Regulation of β-Catenin Signaling by the B56 Subunit of Protein Phosphatase 2A
1999 • 423 citations
The B56 Family of Protein Phosphatase 2A (PP2A) Regulatory Subunits Encodes Differentiation-induced Phosphoproteins That Target PP2A to Both Nucleus and Cytoplasm
1996 • 371 citations
Alterations of the PPP2R1B Gene in Human Lung and Colon Cancer
1998 • 358 citations
Protein phosphatase 2A: a panoply of enzymes
2000 • 328 citations
CDC55, a Saccharomyces cerevisiae Gene Involved in Cellular Morphogenesis: Identification, Characterization, and Homology to the B Subunit of Mammalian Type 2A Protein Phosphatase
1991 • 276 citations
.alpha.- And .beta.-forms of the 65-kDa subunit of protein phosphatase 2A have a similar 39 amino acid repeating structure
1990 • 236 citations
Identification of a New Family of Protein Phosphatase 2A Regulatory Subunits
1995 • 219 citations
Low frequency of alterations of the α (PPP2R1A) and β (PPP2R1B) isoforms of the subunit A of the serine-threonine phosphatase 2A in human neoplasms
2000 • 212 citations
Structure of the 55-kDa regulatory subunit of protein phosphatase 2A: evidence for a neuronal-specific isoform
1991 • 206 citations
Separation of PP2A Core Enzyme and Holoenzyme with Monoclonal Antibodies against the Regulatory A Subunit: Abundant Expression of Both Forms in Cells
1997 • 164 citations
High Complexity in the Expression of the B′ Subunit of Protein Phosphatase 2A0
1996 • 163 citations
CDC55, a Saccharomyces cerevisiae gene involved in cellular morphogenesis: identification, characterization, and homology to the B subunit of mammalian type 2A protein phosphatase.
1991 • 162 citations
Structure and expression of a 72-kDa regulatory subunit of protein phosphatase 2A. Evidence for different size forms produced by alternative splicing
1993 • 149 citations
Disruption of protein phosphatase 2A subunit interaction in human cancers with mutations in the Aα subunit gene
2001 • 144 citations
Molecular model of the A subunit of protein phosphatase 2A: interaction with other subunits and tumor antigens
1994 • 140 citations
Identification of binding sites on the regulatory A subunit of protein phosphatase 2A for the catalytic C subunit and for tumor antigens of simian virus 40 and polyomavirus.
1992 • 134 citations
Loss of Heterozygosity on Chromosome 19 in Secondary Glioblastomas
2000 • 133 citations
Acquisition of the Glioblastoma Phenotype during Astrocytoma Progression Is Associated with Loss of Heterozygosity on 10q25-qter
1999 • 126 citations
Alterations in protein phosphatase 2A subunit interaction in human carcinomas of the lung and colon with mutations in the Aβ subunit gene
2001 • 122 citations
Identification of a Novel Protein Phosphatase 2A Regulatory Subunit Highly Expressed in Muscle
1996 • 121 citations
PR48, a Novel Regulatory Subunit of Protein Phosphatase 2A, Interacts with Cdc6 and Modulates DNA Replication in Human Cells
2000 • 117 citations
Phenotype vs Genotype in the Evolution of Astrocytic Brain Tumors
2000 • 116 citations
Diversity in the Regulatory B-Subunits of Protein Phosphatase 2A: Identification of a Novel Isoform Highly Expressed in Brain
1994 • 113 citations
Different oligomeric forms of protein phosphatase 2A activate and inhibit simian virus 40 DNA replication.
1994 • 109 citations
Induction of p53-Independent Apoptosis by the Adenovirus E4orf4 Protein Requires Binding to the Bα Subunit of Protein Phosphatase 2A
2000 • 101 citations
Functional interaction between a novel protein phosphatase 2A regulatory subunit, PR59, and the retinoblastoma-related p107 protein
1999 • 99 citations
Protein serine/threonine phosphatases and cell transformation
1993 • 92 citations
Alterations of the PPP2R1B gene located at 11q23 in human colorectal cancers
2000 • 91 citations
The third subunit of protein phosphatase 2A (PP2A), a 55-kilodalton protein which is apparently substituted for by T antigens in complexes with the 36- and 63-kilodalton PP2A subunits, bears little resemblance to T antigens
1992 • 84 citations
Adenovirus E4orf4 protein interacts with both Bα and B′ subunits of protein phosphatase 2A, but E4orf4-induced apoptosis is mediated only by the interaction with Bα
2000 • 70 citations
Molecular cloning of a 74‐kDa regulatory subunit (B″ or δ) of human protein phosphatase 2A
1996 • 48 citations
Increasing the Ratio of PP2A Core Enzyme to Holoenzyme Inhibits Tat-Stimulated HIV-1 Transcription and Virus Production
1997 • 48 citations
Genomic organization and precise physical location of protein phosphatase 2A regulatory subunit A beta isoform gene on chromosome band 11q23
1998 • 27 citations
Tissue and Subcellular Distributions, and Characterization of Rat Brain Protein Phosphatase 2A Containing a 72-kDa /B'' Subunit
1997 • 26 citations