Disruption of protein phosphatase 2A subunit interaction in human cancers with mutations in the Aα subunit gene

Inhibitory effect of a marine-sponge toxin, okadaic acid, on protein phosphatases. Specificity and kinetics

1988 • 1,699 citations

Wnt Signaling in Oncogenesis and Embryogenesis--a Look Outside the Nucleus

2000 • 1,253 citations

Protein serine/threonine phosphatases: structure, regulation, and functions in cell growth

1993 • 662 citations

Protein phosphatases come of age

1989 • 616 citations

Okadaic acid: an additional non-phorbol-12-tetradecanoate-13-acetate-type tumor promoter.

1988 • 595 citations

The Structure of the Protein Phosphatase 2A PR65/A Subunit Reveals the Conformation of Its 15 Tandemly Repeated HEAT Motifs

1999 • 434 citations

Regulation of β-Catenin Signaling by the B56 Subunit of Protein Phosphatase 2A

1999 • 423 citations

The B56 Family of Protein Phosphatase 2A (PP2A) Regulatory Subunits Encodes Differentiation-induced Phosphoproteins That Target PP2A to Both Nucleus and Cytoplasm

1996 • 371 citations

Alterations of the PPP2R1B Gene in Human Lung and Colon Cancer

1998 • 358 citations

Protein phosphatase 2A: a panoply of enzymes

2000 • 328 citations

CDC55, a Saccharomyces cerevisiae Gene Involved in Cellular Morphogenesis: Identification, Characterization, and Homology to the B Subunit of Mammalian Type 2A Protein Phosphatase

1991 • 276 citations

.alpha.- And .beta.-forms of the 65-kDa subunit of protein phosphatase 2A have a similar 39 amino acid repeating structure

1990 • 236 citations

Identification of a New Family of Protein Phosphatase 2A Regulatory Subunits

1995 • 219 citations

Low frequency of alterations of the α (PPP2R1A) and β (PPP2R1B) isoforms of the subunit A of the serine-threonine phosphatase 2A in human neoplasms

2000 • 212 citations

Structure of the 55-kDa regulatory subunit of protein phosphatase 2A: evidence for a neuronal-specific isoform

1991 • 206 citations

Comparison of heterotrimeric protein phosphatase 2A containing different B subunits.

1994 • 187 citations

Molecular cloning of cDNAs encoding two isoforms of the catalytic subunit of protein phosphatase 2A

1987 • 165 citations

Separation of PP2A Core Enzyme and Holoenzyme with Monoclonal Antibodies against the Regulatory A Subunit: Abundant Expression of Both Forms in Cells

1997 • 164 citations

High Complexity in the Expression of the B′ Subunit of Protein Phosphatase 2A0

1996 • 163 citations

CDC55, a Saccharomyces cerevisiae gene involved in cellular morphogenesis: identification, characterization, and homology to the B subunit of mammalian type 2A protein phosphatase.

1991 • 162 citations

Structure and expression of a 72-kDa regulatory subunit of protein phosphatase 2A. Evidence for different size forms produced by alternative splicing

1993 • 149 citations

Molecular model of the A subunit of protein phosphatase 2A: interaction with other subunits and tumor antigens

1994 • 140 citations

Identification of binding sites on the regulatory A subunit of protein phosphatase 2A for the catalytic C subunit and for tumor antigens of simian virus 40 and polyomavirus.

1992 • 134 citations

Identification of a Novel Protein Phosphatase 2A Regulatory Subunit Highly Expressed in Muscle

1996 • 121 citations

PR48, a Novel Regulatory Subunit of Protein Phosphatase 2A, Interacts with Cdc6 and Modulates DNA Replication in Human Cells

2000 • 117 citations

Diversity in the Regulatory B-Subunits of Protein Phosphatase 2A: Identification of a Novel Isoform Highly Expressed in Brain

1994 • 113 citations

Different oligomeric forms of protein phosphatase 2A activate and inhibit simian virus 40 DNA replication.

1994 • 109 citations

Functional interaction between a novel protein phosphatase 2A regulatory subunit, PR59, and the retinoblastoma-related p107 protein

1999 • 99 citations

APC: the plot thickens

1999 • 97 citations

Molecular cloning and sequence analysis of the catalytic subunit of bovine type 2A protein phosphatase.

1987 • 96 citations

Protein serine/threonine phosphatases and cell transformation

1993 • 92 citations

Alterations of the PPP2R1B gene located at 11q23 in human colorectal cancers

2000 • 91 citations

Isolation and sequence analysis of a cDNA clone encoding the entire catalytic subunit of a type‐2A protein phosphatase

1987 • 88 citations

Subunit interactions control protein phosphatase 2A. Effects of limited proteolysis, N-ethylmaleimide, and heparin on the interaction of the B subunit

1991 • 85 citations

The third subunit of protein phosphatase 2A (PP2A), a 55-kilodalton protein which is apparently substituted for by T antigens in complexes with the 36- and 63-kilodalton PP2A subunits, bears little resemblance to T antigens

1992 • 84 citations

Expression of the A subunit of protein phosphatase 2A and characterization of its interactions with the catalytic and regulatory subunits.

1992 • 78 citations

Molecular cloning and sequence of cDNA encoding polyoma medium tumor antigen-associated 61-kDa protein.

1989 • 77 citations

Modulation of the Enzymatic Properties of Protein Phosphatase 2A Catalytic Subunit by the Recombinant 65‐kDa Regulatory Subunit PR65α

1997 • 69 citations

Isolation and partial characterization of an Mr 60,000 subunit of a type 2A phosphatase from rabbit reticulocytes

1989 • 59 citations

Increasing the Ratio of PP2A Core Enzyme to Holoenzyme Inhibits Tat-Stimulated HIV-1 Transcription and Virus Production

1997 • 48 citations

Binding Specificity of Protein Phosphatase 2A Core Enzyme for Regulatory B Subunits and T Antigens

1999 • 48 citations

Molecular cloning of a 74‐kDa regulatory subunit (B″ or δ) of human protein phosphatase 2A

1996 • 48 citations

Dilated cardiomyopathy in transgenic mice expressing a mutant A subunit of protein phosphatase 2A

2000 • 46 citations

Molecular cloning of cDNA for the catalytic subunit of rat liver type 2A protein phosphatase, and detection of high levels of expression of the gene in normal and cancer cells

1988 • 45 citations

Different Oligomeric Forms of Protein Phosphatase 2A Activate and Inhibit Simian Virus 40 DNA Replication

1994 • 40 citations

Tissue and Subcellular Distributions, and Characterization of Rat Brain Protein Phosphatase 2A Containing a 72-kDa /B'' Subunit

1997 • 26 citations

Absence of PPP2R1B gene alterations in primary ovarian cancers

1999 • 24 citations