Aquaporin-2 Water Channels and Vasopressin Antagonists in Edematous Disorders

Effects of enalapril on mortality in severe congestive heart failure: Results of the Cooperative North Scandinavian Enalapril Survival Study (CONSENSUS)

1988 • 3,818 citations

Peripheral arterial vasodilation hypothesis: A proposal for the initiation of renal sodium and water retention in cirrhosis

1988 • 1,606 citations

Norepinephrine spillover to plasma in patients with congestive heart failure: evidence of increased overall and cardiorenal sympathetic nervous activity.

1986 • 1,025 citations

Vasopressin increases water permeability of kidney collecting duct by inducing translocation of aquaporin-CD water channels to plasma membrane.

1995 • 1,017 citations

Cloning and expression of apical membrane water channel of rat kidney collecting tubule

1993 • 1,002 citations

Requirement of Human Renal Water Channel Aquaporin-2 for Vasopressin-dependent Concentration of Urine

1994 • 870 citations

Prognostic importance of serum sodium concentration and its modification by converting-enzyme inhibition in patients with severe chronic heart failure.

1986 • 555 citations

Nucleotide sequence of cloned cDNA encoding bovine arginine vasopressin–neurophysin II precursor

1982 • 553 citations

Molecular cloning of the receptor for human antidiuretic hormone

1992 • 529 citations

Cloning and characterization of a vasopressin V2 receptor and possible link to nephrogenic diabetes insipidus

1992 • 519 citations

Pathogenesis of Sodium and Water Retention in High-Output and Low-Output Cardiac Failure, Nephrotic Syndrome, Cirrhosis, and Pregnancy

1988 • 486 citations

Prognostic value of arterial pressure, endogenous vasoactive systems, and renal function in cirrhotic patients admitted to the hospital for the treatment of ascites

1988 • 469 citations

Structure and comparison of the oxytocin and vasopressin genes from rat.

1984 • 411 citations

Radioimmunoassay of Plasma Arginine Vasopressin in Hyponatremic Patients with Congestive Heart Failure

1981 • 377 citations

Prognostic importance of serum sodium concentration and its modification by converting-enzyme inhibition in patients with severe chronic heart failure.

1986 • 372 citations

Characterization of a novel aquaretic agent, OPC‐31260, as an orally effective, nonpeptide vasopressin V₂ receptor antagonist

1992 • 350 citations

Pathogenesis of Sodium and Water Retention in High-Output and Low-Output Cardiac Failure, Nephrotic Syndrome, Cirrhosis, and Pregnancy

1988 • 333 citations

Molecular identification of the gene responsible for congenital nephrogenic diabetes insipidus

1992 • 331 citations

Role of Vasopressin in Abnormal Water Excretion in Cirrhotic Patients

1982 • 308 citations

Redistribution of aquaporin-2 water channels induced by vasopressin in rat kidney inner medullary collecting duct

1995 • 303 citations

Upregulation of aquaporin-2 water channel expression in chronic heart failure rat.

1997 • 289 citations

Body Fluid Volume Regulation in Health and Disease: A Unifying Hypothesis

1990 • 246 citations

THE RELATIONSHIP OF PLASMA VOLUME, PORTAL HYPERTENSION, ASCITES, AND RENAL SODIUM RETENTION IN CIRRHOSIS: THE OVERFLOW THEORY OF ASCITES FORMATION

1970 • 219 citations

Reduced central blood volume in cirrhosis

1989 • 209 citations

Vasopressin increases AQP-CD water channel in apical membrane of collecting duct cells in Brattleboro rats

1995 • 204 citations

Mutations in the vasopressin type 2 receptor gene (AVPR2) associated with nephrogenic diabetes insipidus

1992 • 184 citations

Mutations in the V2 vasopressin receptor gene are associated with X–linked nephrogenic diabetes insipidus

1992 • 179 citations

THE ROLE OF THE KIDNEY IN LAENNECʼS CIRRHOSIS OF THE LIVER

1958 • 153 citations

Isolation of Human Aquaporin 3 Gene

1995 • 152 citations

Osmoregulation during Pregnancy in the Rat

1981 • 143 citations

Role of water channel AQP-CD in water retention in SIADH and cirrhotic rats

1995 • 143 citations

PLASMA OSMOLALITY AND URINARY CONCENTRATION AND DILUTION DURING AND AFTER PREGNANCY: EVIDENCE THAT LATERAL RECUMBENCY INHIBITS MAXIMAL URINARY CONCENTRATING ABILITY

1981 • 138 citations

Peripheral arterial vasodilation hypothesis of sodium and water retention in pregnancy: implications for pathogenesis of preeclampsia-eclampsia.

1991 • 137 citations

Effects of oral AVP receptor antagonists OPC-21268 and OPC-31260 on congestive heart failure in conscious dogs

1994 • 134 citations

Nitric oxide synthase (NOS) inhibition for one week improves renal sodium and water excretion in cirrhotic rats with ascites.

1998 • 130 citations

Upregulation of aquaporin 2 water channel expression in pregnant rats.

1998 • 109 citations

Arginine vasopressin and the renal response to water loading in congestive heart failure

1986 • 108 citations

The Neurohypophyseal Hormones Vasopressin and Oxytocin. Precursor Structure, Synthesis and Regulation

1986 • 106 citations

Interrelationship between cardiac output and vascular resistance as determinants of effective arterial blood volume in cirrhotic patients

1985 • 102 citations

Modulation of plasma and platelet vasopressin by cardiac function in patients with heart failure

1986 • 95 citations

Isolation of human aquaporin-CD gene.

1994 • 89 citations

Therapeutic efficacy of the non-peptide AVP antagonist OPC-31260 in cirrhotic rats

1994 • 83 citations

Effect of V1-vasopressin receptor blockade on arterial pressure in conscious rats with cirrhosis and ascites

1991 • 82 citations

Acute hemodynamic effect of a vascular antagonist of vasopressin in patients with congestive heart failure

1985 • 82 citations

Blockade of the hydroosmotic effect of vasopressin normalizes water excretion in cirrhotic rats

1989 • 66 citations

Role of Antidiuretic Hormone in Impaired Water Excretion of Patients with Congestive Heart Failure*

1984 • 63 citations

Arginine vasopressin gene expression in chronic cardiac failure in rats

1990 • 61 citations

Effect of vasopressin antagonist on water excretion in inferior vena cava constriction

1986 • 59 citations

Vasopressin Gene Expression in Rats with Experimental Cirrhosis

1993 • 56 citations

Vasopressin and Renin in High Output Heart Failure of Rats

1985 • 54 citations

An odyssey into the milieu intérieur

1992 • 27 citations

Recent Observations With $beta;-Adrenoceptor BlockadeBeneficial Effects in Hypertension and Heart Failure

1998 • 18 citations

Arginine vasopressin secretion with mutants of wild-type and Brattleboro rats AVP gene.

1997 • 18 citations

Molecular basis of renal disease. Role of aquaporins in renal water handling: physiology and pathophysiology

1998 • 17 citations

Case 46-1991

1991 • 16 citations

Enhancement of vascular action of arginine vasopressin by diminished extracellular sodium concentration

1993 • 13 citations

Role of Vasopressin in Experimental Congestive Cardiac Failure

1986 • 9 citations