Inhibitors of the GABA uptake systems

PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT

1951 • 319,299 citations

Amino Acid Metabolism in Mammalian Cell Cultures

1959 • 4,025 citations

Chemical Nature of Synaptic Transmission in Vertebrates

1974 • 1,613 citations

Protein Determination of Large Numbers of Samples

1959 • 1,591 citations

Amino acid transmitters in the mammalian central nervous system

1974 • 1,169 citations

THE EXCITATION AND DEPRESSION OF SPINAL NEURONES BY STRUCTURALLY RELATED AMINO ACIDS

1960 • 853 citations

Growth and cultivation of dissociated neurons and glial cells from embryonic chick, rat and human brain in flask cultures.

1972 • 760 citations

Bicuculline, an antagonist of GABA and synaptic inhibition in the spinal cord of the cat

1971 • 685 citations

Properties of γ-aminobutyric acid (GABA) receptor binding in rat brain synaptic membrane fractions

1975 • 637 citations

Uptake and metabolism of γ-aminobutyric acid by neurones and glial cells

1975 • 564 citations

THE UPTAKE OF [³H]GABA BY SLICES OF RAT CEREBRAL CORTEX

1968 • 543 citations

GABA in nervous system function

1976 • 529 citations

Epilepsy and γ-Aminobutyric Acid-Mediated Inhibition

1975 • 491 citations

GABA UPTAKE IN RAT CENTRAL NERVOUS SYSTEM: COMPARISON OF UPTAKE IN SLICES AND HOMOGENATES AND THE EFFECTS OF SOME INHIBITORS

1971 • 417 citations

Pharmacological characterization of different types of GABA and glutamate receptors in vertebrates and invertebrates☆☆☆

1979 • 392 citations

UPTAKE AND METABOLISM OF GLUTAMATE IN ASTROCYTES CULTURED FROM DISSOCIATED MOUSE BRAIN HEMISPHERES

1977 • 343 citations

A new class of GABA agonist

1977 • 338 citations

INHIBITION OF GABA UPTAKE IN RAT BRAIN SLICES BY NIPECOTIC ACID, VARIOUS ISOXAZOLES AND RELATED COMPOUNDS

1975 • 329 citations

Metabolic Compartmentation and Neurotransmission

1975 • 301 citations

STRUCTURE AND BIOLOGICAL ACTIVITY OF A SERIES OF CONFORMATIONALLY RESTRICTED ANALOGUES OF GABA

1975 • 267 citations

The characterisation of [3H]GABA uptake into the satellite glial cells of rat sensory ganglia

1974 • 246 citations

Autoradiographic localisation of [3H]GABA and [3H]glutamate over satellite glial cells

1974 • 230 citations

Use of 3H-muscimol for GABA receptor studies

1978 • 224 citations

δ-Aminolaevulinic acid is a potent agonist for GABA autoreceptors

1979 • 212 citations

INHIBITION OF THE UPTAKE OF GABA AND RELATED AMINO ACIDS IN RAT BRAIN SLICES BY THE OPTICAL ISOMERS OF NIPECOTIC ACID

1976 • 202 citations

Uptake and metabolism of GABA in astrocytes cultured from dissociated mouse brain hemispheres

1977 • 186 citations

DIHYDROMUSCIMOL, THIOMUSCIMOL AND RELATED HETEROCYCLIC COMPOUNDS AS GABA ANALOGUES

1979 • 185 citations

STRUCTURE‐ACTIVITY STUDIES ON THE INHIBITION OF GABA BINDING TO RAT BRAIN MEMBRANES BY MUSCIMOL AND RELATED COMPOUNDS

1978 • 176 citations

Betel nut constituents as inhibitors of γ-aminobutyric acid uptake

1975 • 175 citations

Inhibitors of GABA metabolism

1979 • 170 citations

Exchange of neurotransmitter amino acid at nerve endings can simulate high affinity uptake

1974 • 168 citations

Selective inhibition of neuronal GABA uptake by cis-1,3-aminocyclohexane carboxylic acid

1976 • 163 citations

Is GABA release modulated by presynaptic receptors?

1978 • 144 citations

The inactivation of extracellularly administered amino acids in the feline spinal cord

1970 • 133 citations

EFFECTS OF GABA ANALOGUES OF RESTRICTED CONFORMATION ON GABA TRANSPORT IN ASTROCYTES AND BRAIN CORTEX SLICES AND ON GABA RECEPTOR BINDING

1979 • 133 citations

Influence of inhibitors of the high affinity GABA uptake on seizure thresholds in mice

1979 • 128 citations

A NEW CHEMICAL METHOD FOR QUANTIFYING MELANIN

1976 • 126 citations

Amino acids as chemical transmitters

1980 • 120 citations

GABA—Biochemistry and CNS Functions

1979 • 119 citations

Autoradiographic uptake patterns of [3H]GABA and [3H]-glycine in central nervous tissues with special reference to the cat spinal cord

1973 • 110 citations

Neurochemical correlates of synaptically active amino acids

1974 • 107 citations

COMPETITIVE INHIBITION OF GABA UPTAKE IN RAT BRAIN SLICES BY SOME GABA ANALOGUES OF RESTRICTED CONFORMATION

1972 • 105 citations

Effects of the Areca nut constituents arecaidine and guvacine on the action of GABA in the cat central nervous system

1977 • 103 citations

MUSCIMOL UPTAKE, RELEASE AND BINDING IN RAT BRAIN SLICES

1978 • 102 citations

Taurine uptake in astrocytes cultured from dissociated mouse brain hemispheres

1976 • 100 citations

Neurotransmitter amino acids

1976 • 98 citations

Presynaptic GABA autoreceptors on gabaergic nerve endings of the rat substantia nigra

1979 • 97 citations

The in vivo inactivation of GABA and other inhibitory amino acids in the cat nervous system

1976 • 94 citations

NEURONAL AND GLIAL SYSTEMS FOR γ‐AMINOBUTYRIC ACID TRANSPORT

1975 • 94 citations

Convulsant and anticonvulsant actions in DBA/2 mice of compounds blocking the reuptake of GABA

1979 • 92 citations

GABA UPTAKE IN RAT BRAIN SLICES: INHIBITION BY GABA ANALOGUES AND BY VARIOUS DRUGS

1973 • 92 citations

SODIUM‐DEPENDENT EFFLUX AND EXCHANGE OF GABA IN SYNAPTOSOMES

1974 • 90 citations

High affinity uptake of GABA in presumed GABA-ergic nerve endings in rat brain

1975 • 89 citations

Soft sheets of fibrillar bone from a fossil of the supraorbital horn of the dinosaur Triceratops horridus

2013 • 84 citations

Evidence for net uptake of GABA into mouse astrocytes in primary cultures?Its sodium dependence and potassium independence

1978 • 80 citations

Cis-3-aminocyclohexanecar☐ylic acid: a substrate for the neuronal GABA transport system

1977 • 76 citations

Transport of L-proline by rat brain slices

1976 • 74 citations

Gaba-receptors in the vertebrate nervous system

1977 • 72 citations

Piperidine‐4‐sulphonic Acid, a New Specific GAB A Agonist

1980 • 71 citations

Inhibition of the high-affinity, net uptake of GABA into cultured astrocytes by β-proline, nipecotic acid and other compounds

1978 • 66 citations

NEUROTRANSMITTER UPTAKE INTO SLICES OF RAT CEREBRAL CORTEX IN VITRO: EFFECT OF SLICE SIZE

1976 • 66 citations

The effects of l-2,4-diaminobutyric acid on the uptake of gamma-aminobutyric acid by a synaptosomal fraction from rat brain

1973 • 62 citations

THE CATIONIC COMPOSITION OF INCUBATED CEREBRAL CORTEX SLICES

1968 • 57 citations

Kinetic and pharmacologic characterization of gamma-aminobutyric acid receptive sites from mammalian brain

1979 • 48 citations

Net uptake of gamma-aminobutyric acid by a high affinity synaptosomal transport system.

1977 • 47 citations

Inhibition by Neuroleptics of Uptake of ³H‐GABA into Rat Brain Synaptosomes

1978 • 47 citations

Functional assessment of GABA uptake or exchange by synaptosomal fractions

1976 • 43 citations

High‐Affinity Uptake of (RS)‐Nipecotic Acid in Astrocytes Cultured from Mouse Brain. Comparison with GABA Transport

1980 • 42 citations

High-affinity uptake of ?-aminobutyric acid in cultured glial and neuronal cells

1979 • 42 citations

Role of amino acids and peptides in synaptic transmission

1973 • 40 citations

Organic Hydroxylamine Derivatives. X. Structural Analogues of gamma-Aminobutyric Acid (GABA) of the Isoxazole Enol-betaine Type. Synthesis of 5,6,7,8-Tetrahydro-4H-isoxazolo[4,5-d]azepin-3-ol Zwitterion and 4,5,6,7-Tetrahydroisoxazolo[4,5-c]pyridin-3-ol Zwitterion.

1974 • 33 citations

Does uptake limit the action of GABA agonists in vivo? Experiments with muscimol, isoguvacine and THIP in cat spinal cord

1978 • 32 citations

AMINO ACIDS AS CENTRAL NERVOUS TRANSMITTERS: BIOCHEMICAL STUDIES

1973 • 25 citations

Gaba-neuro-transmitters : pharmacochemical, biochemical, and pharmacological aspects : proceedings of the Alfred Benzon Symposium 12 held at the premises of the Royal Danish Academy of Sciences and Letters, Copenhagen 21-25 May 1978

1979 • 25 citations

A Simple Preparation of Nipecotic Acid

1963 • 22 citations

STEREOSPECIFICITY OF 2,4‐DIAMINOBUTYRIC ACID WITH RESPECT TO INHIBITION OF 4‐AMINOBUTYRIC ACID UPTAKE AND BINDING

1977 • 20 citations

l-2,4-Diaminobutyric acid and the GABA system

1977 • 19 citations

UPTAKE OF [¹⁴C]NIPECOTIC ACID INTO RAT DORSAL ROOT GANGLIA

1979 • 18 citations

High affinity uptake of neurotransmitter amino acids

1975 • 17 citations

Effects of Potassium On Concentrations of Ions and Proteins and On_PH In Brain-Cortex Slices from New-Born and Adult Rats

1971 • 17 citations

Hypocholesteremic Agents. II. The Hydrogenation of Some Pyridinesulfonic and Pyridinealkanesulfonic Acids

1964 • 14 citations

Nipecotic acid and 2,4-diaminobutyric acid enhance the actions of muscimol on cerebral cortical neurons

1978 • 13 citations

EVIDENCE FOR THE HETEROGENEITY OF L‐2,4‐DIAMINOBUTYRIC ACID UPTAKE IN RAT CORTEX

1978 • 8 citations

Pathological chemistry of the nervous system

1972 • 6 citations

[Chemistry of active materials from the fly agaric (Amanita muscaria)].

1969 • 6 citations

Microelectrophoretic effects of (+/-) cis-1,3-aminocyclohexane carboxylic acid on nigral neurones in control and tetanus toxin treated rats [proceedings].

1978 • 3 citations