Immunochemical and immunohistochemical localization of Bcl-x protein in the rat central nervous system

Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programed cell death

1993 • 6,009 citations

bcl-x, a bcl-2-related gene that functions as a dominant regulator of apoptotic cell death

1993 • 3,111 citations

Bad, a heterodimeric partner for Bcl-xL and Bcl-2, displaces bax and promotes cell death

1995 • 2,114 citations

Bcl-2-deficient mice demonstrate fulminant lymphoid apoptosis, polycystic kidneys, and hypopigmented hair

1993 • 1,638 citations

BH1 and BH2 domains of Bcl-2 are required for inhibition of apoptosis and heterodimerization with Bax

1994 • 1,303 citations

BCL2 protein is topographically restricted in tissues characterized by apoptotic cell death.

1991 • 1,301 citations

Massive Cell Death of Immature Hematopoietic Cells and Neurons in Bcl-x-Deficient Mice

1995 • 1,167 citations

Inactivation of Bcl-2 by phosphorylation.

1995 • 744 citations

Induction of apoptosis by the Bcl-2 homologue Bak

1995 • 738 citations

Interactions among members of the Bcl-2 protein family analyzed with a yeast two-hybrid system.

1994 • 590 citations

Beta-amyloid precursor protein of Alzheimer disease occurs as 110- to 135-kilodalton membrane-associated proteins in neural and nonneural tissues.

1988 • 584 citations

Modulation of apoptosis by the widely distributed Bcl-2 homologue Bak

1995 • 514 citations

Cloning of a bcl-2 homologue by interaction with adenovirus E1B 19K

1995 • 501 citations

bcl-xLx is the major bcl-x mRNA form expressed during murine development and its product localizes to mitochondria

1994 • 435 citations

bcl-2 protein expression is widespread in the developing nervous system and retained in the adult PNS

1994 • 432 citations

Immunohistochemical analysis of in vivo patterns of Bcl-X expression.

1994 • 429 citations

Targeted disruption of Bcl-2 alpha beta in mice: occurrence of gray hair, polycystic kidney disease, and lymphocytopenia.

1994 • 396 citations

Characterization of A1, a novel hemopoietic-specific early-response gene with sequence similarity to bcl-2.

1993 • 336 citations

Expression of bcl-2 in fetal tissues suggests a role in morphogenesis.

1993 • 320 citations

Bcl-2 protein expression during murine development.

1994 • 164 citations

Cloning and molecular characterization of mouse bcl-x in B and T lymphocytes.

1994 • 133 citations

bcl-2 Gene Is Highly Expressed during Neurogenesis in the Central Nervous System

1993 • 109 citations

Increased expression of bcl-2 immunoreactivity in the developing cerebral cortex of the rat

1994 • 50 citations

Phospholipase C isozymes in neurons and glial cells in culture: an immunocytochemical and immunochemical study

1991 • 40 citations

Differential distribution of cellular forms of β-amyloid precursor protein in murine glial cell cultures

1992 • 40 citations

Interactions among members of the Bcl-2 protein family analyzed with a yeast two-hybrid system

1995 • 33 citations

High expression of Bcl-x protein in the developing human cerebellar cortex

1996 • 22 citations

Expression of Bcl-2 protein in murine neural cells in culture

1994 • 19 citations

Alzheimer’s Disease β-Amyloid Precursor Protein in Rat Neural Cells in Culture

1992 • 4 citations