Membrane damage by pore-forming bacterial cytolysins

Nucleotide sequence of an Escherichia coli chromosomal hemolysin

1985 • 572 citations

Bacterial toxins and cell membranes

1978 • 471 citations

Mechanism of membrane damage by streptolysin-O

1985 • 398 citations

On the mechanism of membrane damage by Staphylococcus aureus alpha-toxin.

1981 • 369 citations

Diphtheria toxin fragment forms large pores in phospholipid bilayer membranes.

1981 • 341 citations

Cytolytic activity of purified cytoplasmic granules from cytotoxic rat large granular lymphocyte tumors.

1984 • 337 citations

Streptococcal toxins (streptolysin O, streptolysin S, erythrogenic toxin)

1980 • 266 citations

Bacterial Protein Toxins

1985 • 237 citations

Interactions between membranes and cytolytic bacterial toxins

1974 • 225 citations

Mechanism of Cytolysis by Complement

1972 • 222 citations

Membrane damage by complement

1983 • 216 citations

The Lesions in Cell Membranes Caused by Complement

1969 • 209 citations

Formation of transmembrane tubules by spontaneous polymerization of the hydrophilic complement protein C9

1982 • 183 citations

The sequence and topology of human complement component C9.

1985 • 179 citations

Staphylococcal alpha-toxin: oligomerization of hydrophilic monomers to form amphiphilic hexamers induced through contact with deoxycholate detergent micelles.

1981 • 177 citations

Primary sequence of the alpha-toxin gene from Staphylococcus aureus wood 46

1984 • 168 citations

Cytolysis of nucleated cells by complement: cell death displays multi-hit characteristics.

1983 • 167 citations

Nonenteric toxins of Staphylococcus aureus

1979 • 165 citations

Macrophages release arachidonic acid, prostaglandin E2, and thromboxane in response to late complement components.

1984 • 144 citations

Effect of streptolysin O on erythrocyte membranes, liposomes, and lipid dispersions. A protein-cholesterol interaction.

1975 • 142 citations

Elimination of terminal complement intermediates from the plasma membrane of nucleated cells: the rate of disappearance differs for cells carrying C5b-7 or C5b-8 or a mixture of C5b-8 with a limited number of C5b-9.

1985 • 139 citations

Membrane glycoprotein receptor and hole-forming properties of a cytolytic protein toxin

1982 • 137 citations

Staphylococcal alpha-toxin-induced PGI2 production in endothelial cells: role of calcium

1985 • 125 citations

Thiol-activated (oxygen-labile) cytolysins

1978 • 119 citations

Molecular nature of the complement lesion.

1978 • 117 citations

Isolation and identification of two hemolytic forms of streptolysin-O

1984 • 112 citations

Correlation between toxin binding and hemolytic activity in membrane damage by staphylococcal alpha-toxin

1984 • 112 citations

Consequences of cell membrane attack by complement: release of arachidonate and formation of inflammatory derivatives.

1983 • 110 citations

Approximate dimensions of membrane lesions produced by streptolysin S and streptolysin O

1983 • 105 citations

Increased ion permeability of planar lipid bilayer membranes after treatment with the C5b-9 cytolytic attack mechanism of complement.

1976 • 103 citations

Physical States of Staphylococcal α-Toxin

1967 • 103 citations

Sensitive assay for detection of toxin-induced damage to the cytoplasmic membrane of human diploid fibroblasts

1975 • 96 citations

Studies on the binding of staphylococcal 125I-labeled α-toxin to rabbit erythrocytes

1976 • 96 citations

Nonenteric toxins of Staphylococcus aureus.

1979 • 92 citations

Staphylococcal alpha-toxin elicits hypertension in isolated rabbit lungs. Evidence for thromboxane formation and the role of extracellular calcium.

1984 • 81 citations

Transmembrane channel formation by complement: functional analysis of the number of C5b6, C7, C8, and C9 molecules required for a single channel.

1982 • 74 citations

Pseudomonas aeruginosa cytotoxin stimulates prostacyclin production in cultured pulmonary artery endothelial cells: Membrane attack and calcium influx

1985 • 69 citations

Binding and partial inactivation of Staphylococcus aureus alpha-toxin by human plasma low density lipoprotein.

1983 • 67 citations

Humoral immune killing of nucleated cells: mechanisms of complement-mediated attack and target cell defense.

1981 • 67 citations

The Functional Size of the Primary Complement Lesion in Resealed Erythrocyte Membrane Ghosts

1979 • 67 citations

Studies on the terminal stages of immune hemolysis. VI. Osmotic blockers of differing Stokes' radii detect complement-induced transmembrane channels of differing size.

1979 • 65 citations

Permeability changes induced in erthrocyte ghost targets by antibody-dependent cytotoxic effector cells: evidence for membrane pores.

1980 • 62 citations

On the cause and nature of C9-related heterogeneity of terminal complement complexes generated on target erythrocytes through the action of whole serum.

1984 • 59 citations

Membrane damage by complement.

1981 • 57 citations

Effect of calcium ions on staphylococcal alpha-toxin-induced hemolysis of rabbit erythrocytes

1985 • 56 citations

Correlation between the Ability of Tumor Cells to Resist Humoral Immune Attack and Their Ability to Synthesize Lipid

1978 • 54 citations

Common action of certain viruses, toxins, and activated complement: pore formation and its prevention by extracellular Ca2+

1984 • 49 citations

The relationship between channel size and the number of C9 molecules in the C5b-9 complex

1985 • 48 citations

Action of staphylococcal ?-toxin on membranes: Some recent advances

1979 • 41 citations

The relationship between channel size and the number of C9 molecules in the C5b-9 complex.

1985 • 40 citations

Steady-state analysis of tracer exchange across the C5b-9 complement lesion in a biological membrane.

1978 • 40 citations

Complement activation and attack on autologous cell membranes induced by streptolysin-O

1985 • 40 citations

Freeze-fracture analysis of the membrane lesion of human complement.

1983 • 37 citations

Studies on the Terminal Stages of Immune Hemolysis

1979 • 32 citations

Inhibition of complement-induced [14C]sucrose release by intracellular and extracellular monoclonal antibodies to C9: Evidence that C9 is a transmembrane protein

1984 • 27 citations

Permeability changes of Ehrlich mouse ascites tumor cells induced by a cytotoxin from Pseudomonas aeruginosa

1982 • 24 citations

Freeze-fracture analysis of the membrane lesion of complement

1982 • 4 citations

Purification of oligomeric staphylococcal α-toxin by affinity chromatography on Digitonin-Sepharose

1985 • 2 citations