COMPARATIVE STUDIES OF THE EFFECTS OF RECOMBINANT GM-CSF AND GM-CSF ADMINISTERED VIA A POXVIRUS TO ENHANCE THE CONCENTRATION OF ANTIGEN- PRESENTING CELLS IN REGIONAL LYMPH NODES

The Dendritic Cell System and its Role in Immunogenicity

1991 • 4,733 citations

Vaccination with irradiated tumor cells engineered to secrete murine granulocyte-macrophage colony-stimulating factor stimulates potent, specific, and long-lasting anti-tumor immunity.

1993 • 2,828 citations

Dramatic increase in the numbers of functionally mature dendritic cells in Flt3 ligand-treated mice: multiple dendritic cell subpopulations identified.

1996 • 1,129 citations

Growth of factor-dependent hemopoietic precursor cell lines.

1980 • 793 citations

Vaccinia virus: a selectable eukaryotic cloning and expression vector.

1982 • 663 citations

The distinct leukocyte integrins of mouse spleen dendritic cells as identified with new hamster monoclonal antibodies.

1990 • 561 citations

Granulocyte-macrophage colony-stimulating factor: an effective adjuvant for protein and peptide-based vaccines

1996 • 308 citations

Granulocyte-macrophage-colony-stimulating factor enhances immune responses to melanoma-associated peptidesin vivo

1996 • 308 citations

Granulocyte-macrophage colony-stimulating factor augments the primary antibody response by enhancing the function of antigen-presenting cells.

1987 • 299 citations

Novel responses of human skin to intradermal recombinant granulocyte/macrophage-colony-stimulating factor: Langerhans cell recruitment, keratinocyte growth, and enhanced wound healing.

1992 • 265 citations

Structure of the chromosomal gene for granulocyte-macrophage colony stimulating factor: comparison of the mouse and human genes.

1985 • 257 citations

Granulocyte-macrophage colony-stimulating factor: an effective adjuvant for protein and peptide-based vaccines

1996 • 256 citations

Induction of MHC class II on human polymorphonuclear neutrophils by granulocyte/macrophage colony-stimulating factor, IFN-gamma, and IL-3.

1993 • 252 citations

Vaccination with syngeneic, lymphoma-derived immunoglobulin idiotype combined with granulocyte/macrophage colony-stimulating factor primes mice for a protective T-cell response.

1996 • 232 citations

Coordinated events during bacteria-induced DC maturation

1999 • 219 citations

Recovery of immunodeficient mice from a vaccinia virus/IL-2 recombinant infection

1987 • 198 citations

Immunotherapy of prostate cancer in the Dunning rat model: use of cytokine gene modified tumor vaccines.

1994 • 181 citations

Induction of protective host immunity to carcinoembryonic antigen (CEA), a self-antigen in CEA transgenic mice, by immunizing with a recombinant vaccinia-CEA virus.

1999 • 181 citations

Antigen-driven induction of CD11c on intestinal intraepithelial lymphocytes and CD8+ T cells in vivo.

1995 • 171 citations

Induction of antitumor immunity by recombinant vaccinia viruses expressing B7-1 or B7-2 costimulatory molecules.

1994 • 166 citations

Idiotype-cytokine fusion proteins as cancer vaccines. Relative efficacy of IL-2, IL-4, and granulocyte-macrophage colony-stimulating factor.

1994 • 135 citations

Pharmacological administration of granulocyte/macrophage-colony-stimulating factor is of significant importance for the induction of a strong humoral and cellular response in patients immunized with recombinant carcinoembryonic antigen

1998 • 112 citations

Selective induction of immune responses by cytokines coexpressed in recombinant fowlpox virus

1994 • 95 citations

Recombinant Human Granulocyte Macrophage-Colony Stimulating Factor (rhGM-CSF) and Autologous Melanoma Vaccine Mediate Tumor Regression in Patients with Metastatic Melanoma

1999 • 92 citations

Therapeutic efficacy of T cells derived from lymph nodes draining a poorly immunogenic tumor transduced to secrete granulocyte-macrophage colony-stimulating factor.

1996 • 72 citations

Evaluation of tolerability and antibody response after recombinant human granulocyte-macrophage colony-stimulating factor (rhGM-CSF) and a single dose of recombinant hepatitis B vaccine

1996 • 68 citations

Interleukin‐5 expressed by a recombinant virus vector enhances specific mucosal IgA responses in vivo

1993 • 57 citations

Prospective randomized placebo-controlled study of granulocyte-macrophage colony-stimulating factor without stem-cell transplantation after high-dose melphalan in patients with multiple myeloma.

1997 • 43 citations

Immunization With Recombinant Human Granulocyte-Macrophage Colony-Stimulating Factor as a Vaccine Adjuvant Elicits Both a Cellular and Humoral Response to Recombinant Human Granulocyte-Macrophage Colony-Stimulating Factor

1999 • 40 citations

Immunization with a Syngeneic Tumor Infected with Recombinant Vaccinia Virus Expressing Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF) Induces Tumor Regression and Long-Lasting Systemic Immunity

1997 • 37 citations

Induction of autoantibody responses to GM-CSF by hyperimmunization with an Id-GM-CSF fusion protein.

1995 • 27 citations

Lymphocyte and macrophage responses after vaccinia virus infections

1976 • 20 citations

Clearance of Recombinant Vaccinia Virus Expressing IL-2: Role of Local Host Immune Responses

1993 • 19 citations

Comparison of Linear and Branched Peptide Forms (MAPs) in the Induction of T Helper Responses to Point-Mutated ras Immunogens

1996 • 19 citations

Up-regulation of the MHC class II molecules on B cells by peptide ligands.

1994 • 9 citations

Characteristics of lymphoblasts appearing in efferent lymph in response to immunization with vaccinia virus.

1985 • 9 citations

Effect of Recombinant Human Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF) on Chemotherapy-Induced Myelosuppression in Patients with Chronic Lymphocytic Leukemia: A Crossover Study

1997 • 8 citations

Granulocyte-Macrophage Colony Stimulating Factor (rh-GM-CSF) in the Treatment of Chemotherapy-Induced Neutropenia

1995 • 3 citations