Phosphatidylinositol turnover is not a general regulator of neuroblastoma cell differentiation: comparison between two differentiating agents, retinoic acid and γ‐interferon

Direct activation of calcium-activated, phospholipid-dependent protein kinase by tumor-promoting phorbol esters.

1982 • 4,786 citations

Inositol trisphosphate and diacylglycerol as second messengers

1984 • 3,535 citations

Release of Ca2+ from a nonmitochondrial intracellular store in pancreatic acinar cells by inositol-1,4,5-trisphosphate

1983 • 2,596 citations

Identification of a receptor for the morphogen retinoic acid

1987 • 2,007 citations

Effects of vitamin A and its analogs (retinoids) on normal and neoplastic cells

1980 • 1,094 citations

Identification of a second human retinoic acid receptor

1988 • 1,049 citations

Identification and spatial distribution of retinoids in the developing chick limb bud

1987 • 964 citations

Transmembrane signalling by the T cell antigen receptor. Perturbation of the T3-antigen receptor complex generates inositol phosphates and releases calcium ions from intracellular stores.

1985 • 742 citations

Decreased expression of N-myc precedes retinoic acid-induced morphological differentiation of human neuroblastoma

1985 • 644 citations

The polyphosphoinositide phosphodiesterase of erythrocyte membranes

1981 • 614 citations

Thrombin-induced phosphodiesteratic cleavage of phosphatidylinositol bisphosphate in human platelets.

1983 • 394 citations

Retinoic Acid-Induced Growth Inhibition and Morphologic Differentiation of Human Neuroblastoma Cells In Vitro<xref ref-type="fn" rid="fn2">2</xref>

1982 • 384 citations

Thyrotropin-releasing hormone rapidly activates the phosphodiester hydrolysis of polyphosphoinositides in GH3 pituitary cells. Evidence for the role of a polyphosphoinositide-specific phospholipase C in hormone action.

1983 • 292 citations

Diacylglycerol stimulates DNA synthesis and cell division in mouse 3T3 cells: role of Ca2+-sensitive phospholipid-dependent protein kinase.

1984 • 266 citations

Oncogenes, ions, and phospholipids

1985 • 171 citations

Separation of multiple isomers of inositol phosphates formed in GH3 cells

1987 • 138 citations

INTERFERON

1975 • 117 citations

Fluoroaluminates mimic guanosine 5′-[γ-thio]triphosphate in activating the polyphosphoinositide phosphodiesterase of hepatocyte membranes. Role for the guanine nucleotide regulatory protein Gp in signal transduction

1987 • 110 citations

An early decrease in phosphatidylinositol turnover occurs on induction of friend cell differentiation and precedes the decrease in c-myc expression

1985 • 105 citations

An Early Event in the Interferon-Induced Transmembrane Signaling Process

1986 • 91 citations

Noncycling Tumor Cells Are Sensitive Targets for the Antiproliferative Activity of Human Interferon

1979 • 67 citations

Retinoic Acid-Induced Differentiation of Human Neuroblastoma: A Cell Variant System Showing Two Distinct Responses

1986 • 55 citations

Interleukin 2 rapidly stimulates synthesis and breakdown of polyphosphoinositides in interleukin 2-dependent, murine T-cell lines.

1987 • 43 citations

Ultrastructural features of a human neuroblastoma cell line treated with retinoic acid

1985 • 39 citations

Hund's rule

1985 • 25 citations

How Do Retinoids Work

1987 • 23 citations

Interferon and cell differentiation

1986 • 22 citations

Neuroblastoma-An Overview of Laboratory Studies Aimed at Inducing Tumor Regression by Initiation of Differentiation or Administration of Antitumor Drugs

1986 • 9 citations

Interferons do not signal cells through rapid alterations in phosphatidylinositide hydrolysis, cytoplasmic free calcium, or cytoplasmic alkalinization.

1985 • 3 citations