Histone Acetylation Regulates the Time of Replication Origin Firing

Functional Discovery via a Compendium of Expression Profiles

2000 • 2,581 citations

Twenty-Five Years of the Nucleosome, Fundamental Particle of the Eukaryote Chromosome

1999 • 1,774 citations

The localization of replication origins on ARS plasmids in S. cerevisiae

1987 • 1,051 citations

The B-type cyclin kinase inhibitor p40SIC1 controls the G1 to S transition in S. cerevisiae

1994 • 902 citations

Replication Dynamics of the Yeast Genome

2001 • 811 citations

Disruption of Higher-Order Folding by Core Histone Acetylation Dramatically Enhances Transcription of Nucleosomal Arrays by RNA Polymerase III

1998 • 568 citations

Spreading of transcriptional represser SIR3 from telomeric heterochromatin

1996 • 523 citations

Cdc6p-dependent loading of Mcm proteins onto pre-replicative chromatin in budding yeast

1997 • 496 citations

Microarray Deacetylation Maps Determine Genome-Wide Functions for Yeast Histone Deacetylases

2002 • 467 citations

Global histone acetylation and deacetylation in yeast

2000 • 457 citations

Histone acetyltransferase activity of yeast Gcn5p is required for the activation of target genes in vivo

1998 • 444 citations

The in vivo replication origin of the yeast 2μm plasmid

1987 • 437 citations

Highly Specific Antibodies Determine Histone Acetylation Site Usage in Yeast Heterochromatin and Euchromatin

2001 • 436 citations

Transcriptional repression by UME6 involves deacetylation of lysine 5 of histone H4 by RPD3

1998 • 421 citations

Regulation of DNA-replication origins during cell-cycle progression

1998 • 415 citations

Genomewide studies of histone deacetylase function in yeast

2000 • 415 citations

Formation of a Preinitiation Complex by S-phase Cyclin CDK-Dependent Loading of Cdc45p onto Chromatin

1998 • 326 citations

Assembly of a Complex Containing Cdc45p, Replication Protein A, and Mcm2p at Replication Origins Controlled by S-Phase Cyclin-Dependent Kinases and Cdc7p-Dbf4p Kinase

2000 • 322 citations

Histone Acetyltransferase HBO1 Interacts with the ORC1 Subunit of the Human Initiator Protein

1999 • 315 citations

Nuclear localization and histone acetylation: a pathway for chromatin opening and transcriptional activation of the human β-globin locus

2000 • 312 citations

Time of replication of yeast centromeres and telomeres

1988 • 295 citations

The origin recognition complex: from simple origins to complex functions

2002 • 290 citations

The Cdc7 protein kinase is required for origin firing during S phase

1998 • 282 citations

Genome-wide binding map of the histone deacetylase Rpd3 in yeast

2002 • 279 citations

The arrest of replication forks in the rDNA of yeast occurs independently of transcription

1992 • 271 citations

[46] Analysis of replication intermediates by two-dimensional agarose gel electrophoresis

1995 • 270 citations

A position effect on the time of replication origin activation in yeast

1992 • 263 citations

Replication program of active and inactive multigene families in mammalian cells.

1988 • 247 citations

Differential assembly of Cdc45p and DNA polymerases at early and late origins of DNA replication

1999 • 241 citations

Histone deacetylase activity of Rpd3 is important for transcriptional repression in vivo

1998 • 235 citations

A yeast origin of replication is activated late in S phase

1991 • 204 citations

Microbial Determinations by Flow Cytometry

1979 • 203 citations

Gcn4 Activator Targets Gcn5 Histone Acetyltransferase to Specific Promoters Independently of Transcription

2000 • 201 citations

Replication Factors MCM2 and ORC1 Interact with the Histone Acetyltransferase HBO1

2001 • 194 citations

The Positioning and Dynamics of Origins of Replication in the Budding Yeast Nucleus

2001 • 186 citations

CLB5-Dependent Activation of Late Replication Origins in S. cerevisiae

1998 • 176 citations

Telomeric chromatin modulates replication timing near chromosome ends

1999 • 172 citations

Interactions of Isw2 Chromatin Remodeling Complex with Nucleosomal Arrays: Analyses Using Recombinant Yeast Histones and Immobilized Templates

2001 • 169 citations

Cell Cycle-Dependent Establishment of a Late Replication Program

1997 • 160 citations

Replication profile of Saccharomyces cerevisiae chromosome VI

1997 • 158 citations

Multiple determinants controlling activation of yeast replication origins late in S phase.

1996 • 148 citations

Biochemical Function of Mouse Minichromosome Maintenance 2 Protein

1998 • 139 citations

Binding of Human Minichromosome Maintenance Proteins with Histone H3

1996 • 127 citations

A role for the Cdc7 kinase regulatory subunit Dbf4p in the formation of initiation-competent origins of replication

1999 • 120 citations

Time of Replication of ARS Elements along Yeast Chromosome III

1989 • 115 citations

Long-Distance Control of Origin Choice and Replication Timing in the Human β-Globin Locus Are Independent of the Locus Control Region

2000 • 113 citations

Factors affecting the timing and imprinting of replication on a mammalian chromosome

1995 • 83 citations

Mcm2 and Mcm3 are constitutive nuclear proteins that exhibit distinct isoforms and bind chromatin during specific cell cycle stages of Saccharomyces cerevisiae.

1997 • 70 citations

The replication timing program of the Chinese hamster β-globin locus is established coincident with its repositioning near peripheral heterochromatin in early G1 phase

2001 • 69 citations

Time of replication of ARS elements along yeast chromosome III.

1989 • 59 citations

Disturbance of Normal Cell Cycle Progression Enhances the Establishment of Transcriptional Silencing in Saccharomyces cerevisiae

1995 • 47 citations

A role for a replicator dominance mechanism in silencing

1999 • 36 citations

Identification of a Compound Origin of Replication at theHMR-E Locus in Saccharomyces cerevisiae

1999 • 20 citations