The Protein Network of HIV Budding

Proteomic Analysis of Dendritic Cell-Derived Exosomes: A Secreted Subcellular Compartment Distinct from Apoptotic Vesicles

2001 • 1,492 citations

Tsg101 and the Vacuolar Protein Sorting Pathway Are Essential for HIV-1 Budding

2001 • 1,351 citations

Receptor downregulation and multivesicular-body sorting

2002 • 1,192 citations

Exosome: from internal vesicle of the multivesicular body to intercellular signaling device

2000 • 1,033 citations

Escrt-III

2002 • 854 citations

AIP1/ALIX Is a Binding Partner for HIV-1 p6 and EIAV p9 Functioning in Virus Budding

2003 • 810 citations

Spread of HTLV-I Between Lymphocytes by Virus-Induced Polarization of the Cytoskeleton

2003 • 711 citations

HIV-1 and Ebola virus encode small peptide motifs that recruit Tsg101 to sites of particle assembly to facilitate egress

2001 • 706 citations

Recruitment of HIV and Its Receptors to Dendritic Cell-T Cell Junctions

2003 • 692 citations

Effect of mutations affecting the p6 gag protein on human immunodeficiency virus particle release.

1991 • 644 citations

Endosome-Associated Complex, ESCRT-II, Recruits Transport Machinery for Protein Sorting at the Multivesicular Body

2002 • 629 citations

The Trojan exosome hypothesis

2003 • 600 citations

Tsg101, a homologue of ubiquitin-conjugating (E2) enzymes, binds the L domain in HIV type 1 Pr55 ^Gag

2001 • 576 citations

Infectious HIV-1 assembles in late endosomes in primary macrophages

2003 • 477 citations

Hrs regulates multivesicular body formation via ESCRT recruitment to endosomes

2003 • 448 citations

Vps27 recruits ESCRT machinery to endosomes during MVB sorting

2003 • 445 citations

Viral Late Domains

2002 • 418 citations

Mammalian Tumor Susceptibility Gene 101 (TSG101) and the Yeast Homologue, Vps23p, Both Function in Late Endosomal Trafficking

2000 • 401 citations

Overexpression of the N-terminal domain of TSG101 inhibits HIV-1 budding by blocking late domain function

2002 • 349 citations

Proteolytic refolding of the HIV-1 capsid protein amino-terminus facilitates viral core assembly

1998 • 337 citations

Human Macrophages Accumulate HIV‐1 Particles in MHC II Compartments

2002 • 320 citations

STAM and Hrs Are Subunits of a Multivalent Ubiquitin-binding Complex on Early Endosomes

2003 • 306 citations

TSG101 interaction with HRS mediates endosomal trafficking and receptor down-regulation

2003 • 298 citations

Structure and functional interactions of the Tsg101 UEV domain

2002 • 294 citations

Overlapping Motifs (PTAP and PPEY) within the Ebola Virus VP40 Protein Function Independently as Late Budding Domains: Involvement of Host Proteins TSG101 and VPS-4

2003 • 277 citations

Mammalian class E vps proteins recognize ubiquitin and act in the removal of endosomal protein–ubiquitin conjugates

2002 • 264 citations

Localization of Human Immunodeficiency Virus Type 1 Gag and Env at the Plasma Membrane by Confocal Imaging

2000 • 263 citations

Mechanisms of enveloped RNA virus budding

2002 • 263 citations

HIV Gag mimics the Tsg101-recruiting activity of the human Hrs protein

2003 • 248 citations

Role of ESCRT-I in Retroviral Budding

2003 • 243 citations

Structure of the Tsg101 UEV domain in complex with the PTAP motif of the HIV-1 p6 protein

2002 • 235 citations

Equine infectious anemia virus utilizes a YXXL motif within the late assembly domain of the Gag p9 protein

1997 • 210 citations

Bro1 is an endosome-associated protein that functions in the MVB pathway in Saccharomyces cerevisiae

2003 • 207 citations

Highly Purified Human Immunodeficiency Virus Type 1 Reveals a Virtual Absence of Vif in Virions

1999 • 206 citations

The Late Domain of Human Immunodeficiency Virus Type 1 p6 Promotes Virus Release in a Cell Type-Dependent Manner

2002 • 200 citations

Biochemical and Structural Analysis of Isolated Mature Cores of Human Immunodeficiency Virus Type 1

2000 • 196 citations

In Vitro Assembly Properties of Purified Bacterially Expressed Capsid Proteins of Human Immunodeficiency Virus

1997 • 193 citations

Hrs Is Associated with STAM, a Signal-transducing Adaptor Molecule

1997 • 185 citations

TSG101/Mammalian VPS23 and Mammalian VPS28 Interact Directly and Are Recruited to VPS4-induced Endosomes

2001 • 182 citations

Alix (ALG-2-interacting Protein X), a Protein Involved in Apoptosis, Binds to Endophilins and Induces Cytoplasmic Vacuolization

2002 • 168 citations

YPXL/I Is a Protein Interaction Motif Recognized by Aspergillus PalA and Its Human Homologue, AIP1/Alix

2003 • 154 citations

Retroviral Genomic RNAs Are Transported to the Plasma Membrane by Endosomal Vesicles

2003 • 152 citations

CHMP1 functions as a member of a newly defined family of vesicle trafficking proteins

2001 • 149 citations

A dominant negative form of the AAA ATPase SKD1/VPS4 impairs membrane trafficking out of endosomal/lysosomal compartments: class Evpsphenotype in mammalian cells

2002 • 126 citations

Equine Infectious Anemia Virus Gag Polyprotein Late Domain Specifically Recruits Cellular AP-2 Adapter Protein Complexes during Virion Assembly

1998 • 118 citations

Actin-Binding Cellular Proteins inside Human Immunodeficiency Virus Type 1

2000 • 117 citations

Mammalian Cells Express Two VPS4 Proteins Both of Which are Involved in Intracellular Protein Trafficking

2001 • 95 citations

Development and Characterization of an In Vivo Pathogenic Molecular Clone of Equine Infectious Anemia Virus

1998 • 69 citations

The Late-Domain-Containing Protein p6 Is the Predominant Phosphoprotein of Human Immunodeficiency Virus Type 1 Particles

2002 • 56 citations

Cloning and Characterization of ELL-associated Proteins EAP45 and EAP20

2001 • 54 citations

Opportunities and challenges in targeting HIV entry

2002 • 14 citations