Production of interleukin-12 and expression of its receptors by murine microglia

Identification and purification of natural killer cell stimulatory factor (NKSF), a cytokine with multiple biologic effects on human lymphocytes.

1989 • 1,989 citations

Tumor necrosis factor mediates myelin and oligodendrocyte damage in vitro

1988 • 1,371 citations

Astrocytes present myelin basic protein to encephalitogenic T-cell lines

1984 • 773 citations

Purification to homogeneity and partial characterization of cytotoxic lymphocyte maturation factor from human B-lymphoblastoid cells.

1990 • 679 citations

Antigen presentation and tumor cytotoxicity by interferon‐γ‐treated microglial cells

1987 • 648 citations

Proliferation of astrocytes in vitro in response to cytokines. A primary role for tumor necrosis factor.

1990 • 548 citations

Cloning and expression of murine IL-12.

1992 • 474 citations

Expression of costimulatory molecules B7-1 (CD80), B7-2 (CD86), and interleukin 12 cytokine in multiple sclerosis lesions.

1995 • 473 citations

Mouse interleukin‐12 (IL‐12) p40 homodimer: a potent IL‐12 antagonist

1995 • 441 citations

Mouse monoclonal antibodies against rat major histocompatibility antigens. Two Ia antigens and expression of Ia and class I antigens in rat thymus

1982 • 364 citations

MHC antigen expression on bulk isolated macrophage-microglia from newborn mouse brain: induction of Ia antigen expression by γ-interferon

1987 • 346 citations

IL-12 receptor. II. Distribution and regulation of receptor expression.

1992 • 298 citations

Gamma-interferon promotes proliferation of adult human astrocytes in vitro and reactive gliosis in the adult mouse brain in vivo.

1991 • 217 citations

Effects of colony stimulating factors on isolated microglia in vitro

1990 • 216 citations

Self-antigen-induced Th2 responses in experimental allergic encephalomyelitis (EAE)-resistant mice. Th2-mediated suppression of autoimmune disease.

1995 • 203 citations

TNFα induces IL-6 production by astrocytes but not by microglia

1992 • 185 citations

Cloning and characterization of a mouse IL-12 receptor-beta component.

1995 • 155 citations

Soluble tumor necrosis factor receptor inhibits interleukin 12 production by stimulated human adult microglial cells in vitro.

1996 • 100 citations

Tumor necrosis factor induces expression of MHC class I antigens on mouse astrocytes

1988 • 91 citations

Selective induction of interleukin-6 in mouse microglia by granulocyte-macrophage colony-stimulating factor

1996 • 56 citations

Induction of MHC class II antigen expression on murine microglia by interleukin-3

1994 • 29 citations

Expression of H-2 antigen on oligodendrocytes is induced by soluble factors from concanavalin A activated T cells

1985 • 26 citations

The production of typhoid antibodies in rabbits with the use of living typhoid organisms adsorbed on aluminum cream.

1946 • 1 citations