Eukaryote genome duplication - where's the evidence?

Basic local alignment search tool

1990 • 87,358 citations

Evolution by gene duplication

1970 • 5,849 citations

Molecular evidence for an ancient duplication of the entire yeast genome

1997 • 1,786 citations

Comparative genetics in the grasses

1998 • 960 citations

Gene duplications and the origins of vertebrate development

1994 • 951 citations

An evolutionary perspective on synonymous codon usage in unicellular organisms

1986 • 874 citations

Vertebrate genome evolution and the zebrafish gene map

1998 • 823 citations

Evolution of genetic redundancy

1997 • 744 citations

DNA sequence evidence for the segmental allotetraploid origin of maize

1997 • 696 citations

Cereal Genome Evolution: Grasses, line up and form a circle

1995 • 690 citations

Comparative linkage maps of the rice and maize genomes.

1993 • 648 citations

The ParaHox gene cluster is an evolutionary sister of the Hox gene cluster

1998 • 481 citations

Evolution of the Vertebrate Genome as Reflected in Paralogous Chromosomal Regions in Man and the House Mouse

1993 • 475 citations

Gen(om)e duplications in the evolution of early vertebrates

1996 • 452 citations

How often do duplicated genes evolve new functions?

1995 • 414 citations

Ligand binding was acquired during evolution of nuclear receptors

1997 • 407 citations

Identification of the genomic locations of duplicate nucleotide sequences in maize by analysis of restriction fragment length polymorphisms.

1988 • 388 citations

Gene Families: The Taxonomy of Protein Paralogs and Chimeras

1997 • 387 citations

Ancient Linkage Groups and Frozen Accidents

1973 • 338 citations

How many genes in the human genome?

1994 • 298 citations

Vertebrate evolution by interspecific hybridisation – are we polyploid?

1997 • 291 citations

Zebrafish hox genes: genomic organization and modified colinear expression patterns in the trunk

1998 • 256 citations

Comparative mapping of Arabidopsis thaliana and Brassica oleracea chromosomes reveals islands of conserved organization.

1994 • 254 citations

Comparable Rates of Gene Loss and Functional Divergence After Genome Duplications Early in Vertebrate Evolution

1997 • 229 citations

Evolution of duplicate genes in a tetraploid animal, Xenopus laevis.

1993 • 228 citations

Two steps in the evolution of Antennapedia-class vertebrate homeobox genes.

1989 • 212 citations

Ancient large-scale genome duplications: phylogenetic and linkage analyses shed light on chordate genome evolution

1998 • 209 citations

Evolutionary origins and maintenance of redundant gene expression during metazoan development

1997 • 186 citations

Chromosomal localization of the proteasome Z subunit gene reveals an ancient chromosomal duplication involving the major histocompatibility complex.

1996 • 172 citations

Paralogy Mapping: Identification of a Region in the Human MHC Triplicated onto Human Chromosomes 1 and 9 Allows the Prediction and Isolation of NovelPBXandNOTCHLoci

1996 • 152 citations

Phylogenetic reconstruction of vertebrate Hox cluster duplications

1997 • 152 citations

Organization of the Fugu rubripes Hox clusters: evidence for continuing evolution of vertebrate Hox complexes

1997 • 151 citations

Gene duplication in tetraploid fish: model for gene silencing at unlinked duplicated loci.

1978 • 141 citations

Sequencing the Human Genome

1997 • 138 citations

Information enhancement methods for large scale sequence analysis

1993 • 133 citations

Zooming in on the Human–Mouse Comparative Map: Genome Conservation Re-examined on a High-Resolution Scale

1997 • 133 citations

Extent of genomic rearrangement after genome duplication in yeast

1998 • 127 citations

Gene number in an invertebrate chordate, Ciona intestinalis

1998 • 126 citations

Genetic redundancy in vertebrates: polyploidy and persistence of genes encoding multidomain proteins

1998 • 120 citations

Evidence for Ancient Tetraploidy and Conservation of Linkage Groups in Mammalian Chromosomes

1972 • 118 citations

Steroid receptor phylogeny and vertebrate origins

1997 • 117 citations

Evolution of gene order and chromosome number inSaccharomyces,Kluyveromyces and related fungi

1998 • 117 citations

Phylogenetic tests of the hypothesis of block duplication of homologous genes on human chromosomes 6, 9, and 1

1998 • 115 citations

Gene loss and gain in the evolution of the vertebrates

1994 • 113 citations

Evolution of gene families and relationship with organismal evolution: rapid divergence of tissue-specific genes in the early evolution of chordates

1996 • 108 citations

Conservation, Duplication, and Divergence of Developmental Genes During Chordate Evolution

1995 • 81 citations

Estimation of Hox gene cluster number in lampreys.

1998 • 64 citations

A comparative study of duplications in bacteria and eukaryotes: the importance of telomeres

1997 • 59 citations

Hox gene variation and evolution

1998 • 57 citations

Evolutionary significance of intra-genome duplications on human chromosomes

1997 • 57 citations

New Insights into the Genomic Organization and Origin of the Major Histocompatibility Complex: Role of Chromosomal (genome) Duplication in the Emergence of the Adaptive Immune System

2004 • 54 citations

Advanced techniques in chromosome research

1991 • 36 citations

The Notion of the Cambrian Pananimalia Genome and a Genomic Difference that Separated Vertebrates from Invertebrates

1998 • 19 citations