Delayed and Reduced Adaptive Humoral Immune Responses in Children with Shigellosis Compared with in Adults

Global burden of Shigella infections: implications for vaccine development and implementation of control strategies.

1999 • 1,261 citations

Classification and definition of protein-calorie malnutrition.

1972 • 994 citations

Bacterial pathogenesis: A molecular approach

1995 • 456 citations

A bacterial invasin induces macrophage apoptosis by binding directly to ICE.

1996 • 405 citations

Mucosal adjuvant effect of cholera toxin in mice results from induction of T helper 2 (Th2) cells and IL-4.

1995 • 392 citations

IgG2 subclass restriction of antibody to pneumococcal polysaccharides.

1986 • 259 citations

Mucosal Antitoxic and Antibacterial Immunity after Cholera Disease and after Immunization with a Combined B Subunit-Whole Cell Vaccine

1984 • 235 citations

Regulation of human IgG subclass production by cytokines. IFN-gamma and IL-6 act antagonistically in the induction of human IgG1 but additively in the induction of IgG2.

1994 • 227 citations

Immunity in Shigellosis. II. Protection Induced by Oral Live Vaccine or Primary Infection

1972 • 207 citations

Plasma anti-pneumococcal antibody activity of the IgG class and subclasses in otitis prone children.

1984 • 179 citations

Monoclonal immunoglobulin A antibody directed against serotype-specific epitope of Shigella flexneri lipopolysaccharide protects against murine experimental shigellosis.

1995 • 168 citations

A novel two colour ELISPOT assay

1988 • 166 citations

Enteropathogens Associated with Acute and Persistent Diarrhea in BangladeshiChildren <5 Years of Age

1992 • 159 citations

Prospective study of the association between serum antibodies to lipopolysaccharide O antigen and the attack rate of shigellosis

1991 • 158 citations

Serum Antibodies to Lipopolysaccharide and Natural Immunity to Shigellosis in an Israeli Military Population

1988 • 155 citations

Studies in volunteers to evaluate candidate Shigella vaccines: further experience with a bivalent Salmonella typhi-Shigella sonnei vaccine and protection conferred by previous Shigella sonnei disease

1990 • 145 citations

Death in Shigellosis: Incidence and Risk Factors in Hospitalized Patients

1990 • 125 citations

Cytokine Secretion in Acute Shigellosis Is Correlated to Disease Activity and Directed More to Stool than to Plasma

1995 • 124 citations

Prospective study of systemic and mucosal immune responses in dysenteric patients to specific Shigella invasion plasmid antigens and lipopolysaccharides

1991 • 99 citations

Age-Associated Differences in Immunoglobulin G1 (IgG1) and IgG2 Subclass Antibodies to Pneumococcal Polysaccharides following Vaccination

1999 • 77 citations

Innate Immune Responses in Children and Adults with Shigellosis

2000 • 65 citations

Immunoglobulin subclass distribution and dynamics of Shigella-specific antibody responses in serum and stool samples in shigellosis

1995 • 62 citations

Age-Specific Prevalence of Serum Antibodies to the Invasion Plasmid and Lipopolysaccharide Antigens of Shigella Species in Chilean and North American Populations

1992 • 54 citations

Computerized assessment of production of multiple human cytokines at the single-cell level using image analysis

1996 • 49 citations

Local and Systemic Antibody Responses to Shigella Infection in Rhesus Monkeys

1987 • 48 citations

Dysentery, not watery diarrhoea, is associated with stunting in Bangladeshi children.

1987 • 45 citations

Comparison of cytokine production in blood cell cultures of healthy children and adults

1995 • 31 citations

Dissociation between cytokine mRNA expression and protein production in shigellosis

1996 • 30 citations

Quantification of superantigen induced IFN-γ production by computerised image analysis — inhibition of cytokine production and blast transformation by pooled human IgG

1994 • 25 citations

Immunoglobulin G (IgG) and IgA subclass pattern of human antibodies to Shigella flexneri and Salmonella serogroup B and D lipopolysaccharide O antigens

1986 • 21 citations

Immune responses to Shigella dysenteriae 1 and Shigella flexneri lipopolysaccharide and polysaccharide antigens in Bangladeshi patients with shigellosis

1993 • 16 citations

Quantitative single cell methods that identify cytokine and chemokine expression in dendritic cells

2001 • 15 citations

Selective correlation of interferon‐γ, tumour necrosis factor‐α and granulocyte–macrophage colony‐stimulating factor with immunoglobulin G1 and immunoglobulin G3 subclass antibody in leprosy

1999 • 14 citations

Social and Behavioral Factors in Transmission and Response to Shigellosis

1991 • 11 citations

Antimicrobial Therapy for Shigellosis: Issues on Antimicrobial Resistance

1998 • 6 citations

Regulation of isotype immunoglobulin and interleukin production by adjuvants in vitro.

1990 • 6 citations

Lymphocyte Subset Profile of Young Healthy Children Residing in a Rural Area: Possible Role of Recurrent Gastrointestinal Infections

1999 • 4 citations