Depth of invasion parallels increased cyclooxygenase-2 levels in patients with gastric carcinoma

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Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction

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1995 • 2,308 citations

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1996 • 1,987 citations

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Cyclooxygenase-2 expression in human colon cancer cells increases metastatic potential

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1995 • 1,135 citations

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Increased expression of cyclooxygenase 2 occurs frequently in human lung cancers, specifically in adenocarcinomas.

1998 • 825 citations

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Prostaglandin endoperoxide synthase: regulation of enzyme expression

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Characterization of Prostaglandin G/H Synthase 1 and 2 in rat, dog, monkey, and human gastrointestinal tracts

1996 • 474 citations

Photolabeling of Prostaglandin Endoperoxide H Synthase-1 with 3-Trifluoro-3-(m-[125I]iodophenyl)diazirine as a Probe of Membrane Association and the Cyclooxygenase Active Site

1996 • 460 citations

Eicosanoids and the gastrointestinal tract

1995 • 426 citations

Cyclooxygenase-2 Overexpression Enhances Lymphatic Invasion and Metastasis in Human Gastric Carcinoma

1999 • 281 citations

Cyclooxygenase-2 inhibitors suppress the growth of gastric cancer xenografts via induction of apoptosis in nude mice

1998 • 236 citations

Size- and invasion-dependent increase in cyclooxygenase 2 levels in human colorectal carcinomas

1999 • 224 citations

Expression of cyclooxygenase-2 protein in gastric adenocarcinoma

1998 • 127 citations

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1996 • 115 citations

Aspirin and Related Nonsteroidal Anti-inflammatory Drugs as Chemopreventive Agents Against Colon Cancer

1995 • 83 citations

Effects of NSAIDs on Proliferation of Gastric Cancer Cells In Vitro: Possible Implication of Cyclooxygenase-2 in Cancer Development

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Overexpression of cyclooxygenase-2 protein is less frequent in gastric cancers with microsatellite instability

1999 • 70 citations

Roles of COX-1 and COX-2 in gastrointestinal pathophysiology

1998 • 57 citations