Apolipoprotein E genotyping in the differential diagnosis, not prediction, of Alzheimer's disease

Clinical diagnosis of Alzheimer's disease

1984 • 27,279 citations

Gene Dose of Apolipoprotein E Type 4 Allele and the Risk of Alzheimer's Disease in Late Onset Families

1993 • 8,888 citations

The Consortium to Establish a Registry for Alzheimer's Disease (CERAD)

1991 • 4,669 citations

Segregation of a missense mutation in the amyloid precursor protein gene with familial Alzheimer's disease

1991 • 4,533 citations

Apolipoprotein E: high-avidity binding to beta-amyloid and increased frequency of type 4 allele in late-onset familial Alzheimer disease.

1993 • 4,145 citations

Association of apolipoprotein E allele ϵ4 with late‐onset familial and sporadic Alzheimer's disease

1993 • 3,693 citations

Diagnosis of Alzheimer's Disease

1985 • 2,482 citations

Protective effect of apolipoprotein E type 2 allele for late onset Alzheimer disease

1994 • 1,813 citations

Apolipoprotein E in sporadic Alzheimer's disease: Allelic variation and receptor interactions

1993 • 1,092 citations

Apolipoprotein E polymorphism and Alzheimer's disease

1993 • 1,076 citations

Genetic Linkage Evidence for a Familial Alzheimer's Disease Locus on Chromosome 14

1992 • 941 citations

Linkage studies in familial Alzheimer disease: evidence for chromosome 19 linkage.

1991 • 762 citations

Apolipoprotein E ∈4 allele distributions in late-onset Alzheimer's disease and in other amyloid-forming diseases

1993 • 504 citations

Apolipoprotein E4 allele in a population–based study of early–onset Alzheimer's disease

1994 • 449 citations

Making the diagnosis of Alzheimer's disease. A primer for practicing pathologists.

1993 • 408 citations

The apolipoprotein ε4 allele in patients with Alzheimer's disease

1993 • 401 citations

Apolipoprotein E Affects the Rate of Alzheimer Disease Expression: β-Amyloid Burden Is a Secondary Consequence Dependent on APOE Genotype and Duration of Disease

1994 • 332 citations

Apolipoprotein E: risk factor for Alzheimer disease.

1994 • 253 citations

Elevation of microtubule-associated protein tau in the cerebrospinal fluid of patients with Alzheimer's disease

1995 • 223 citations

Association of apolipoprotein E phenotypes with late onset Alzheimer's disease: population based study

1994 • 201 citations

Genetic linkage studies in Alzheimer's disease families

1988 • 163 citations

Cerebrospinal fluid concentration of neuron-specific enolase in diagnosis of Creutzfeldt-Jakob disease

1995 • 162 citations

The apolipoprotein E allele epsi;4 is overrepresented in patients with the Lewy body variant of Alzheimer's disease

1994 • 132 citations

The apolipoprotein E alleles as major susceptibility factors for Creutzfeldt-Jakob disease

1994 • 131 citations

The apolipoprotein E ε2 allele is associated with an increased risk of early‐onset alzheimer's disease and a reduced survival

1995 • 130 citations

Dendritic pathology of granule cells in Alzheimer's disease is unrelated to neuritic plaques

1994 • 98 citations

The apolipoprotein E/CI/CII gene cluster and late-onset Alzheimer disease.

1994 • 90 citations

Apolipoprotein E ϵ4 allele frequency in patients with Lewy body dementia, Alzheimer's disease and age-matched controls

1994 • 69 citations

Confirmation of association between the e4 allele of apolipoprotein E and Alzheimer's disease.

1994 • 65 citations

Molecular analysis of late onset Huntington's disease.

1993 • 64 citations

ApoE ϵ4 allelic association with Alzheimer's disease

1994 • 59 citations

[Alzheimer disease. Strong connection between apolipoprotein E and disease development].

1994 • 2 citations