Input organization and plasticity of hypocretin neurons

The hypocretins: Hypothalamus-specific peptides with neuroexcitatory activity

1998 • 3,711 citations

The Synaptic Organization of the Brain

2004 • 3,543 citations

Neurons Containing Hypocretin (Orexin) Project to Multiple Neuronal Systems

1998 • 3,381 citations

Narcolepsy in orexin Knockout Mice

1999 • 3,014 citations

The Sleep Disorder Canine Narcolepsy Is Caused by a Mutation in the Hypocretin (Orexin) Receptor 2 Gene

1999 • 2,583 citations

Brief Communication: Sleep Curtailment in Healthy Young Men Is Associated with Decreased Leptin Levels, Elevated Ghrelin Levels, and Increased Hunger and Appetite

2004 • 2,291 citations

Short Sleep Duration Is Associated with Reduced Leptin, Elevated Ghrelin, and Increased Body Mass Index

2004 • 2,277 citations

A mutation in a case of early onset narcolepsy and a generalized absence of hypocretin peptides in human narcoleptic brains

2000 • 2,065 citations

The Distribution and Mechanism of Action of Ghrelin in the CNS Demonstrates a Novel Hypothalamic Circuit Regulating Energy Homeostasis

2003 • 1,617 citations

Genetic Ablation of Orexin Neurons in Mice Results in Narcolepsy, Hypophagia, and Obesity

2001 • 1,387 citations

The melanin‐concentrating hormone system of the rat brain: An immuno‐ and hybridization histochemical characterization

1992 • 1,052 citations

Orexins, orexigenic hypothalamic peptides, interact with autonomic, neuroendocrine and neuroregulatory systems

1999 • 1,028 citations

Rapid Rewiring of Arcuate Nucleus Feeding Circuits by Leptin

2004 • 975 citations

Hypothalamic Orexin Neurons Regulate Arousal According to Energy Balance in Mice

2003 • 892 citations

Chemically defined projections linking the mediobasal hypothalamus and the lateral hypothalamic area

1998 • 817 citations

On the Interactions of the Hypothalamic-Pituitary-Adrenal (HPA) Axis and Sleep: Normal HPA Axis Activity and Circadian Rhythm, Exemplary Sleep Disorders

2005 • 797 citations

Hypocretin/Orexin- and melanin-concentrating hormone-expressing cells form distinct populations in the rodent lateral hypothalamus: Relationship to the neuropeptide Y and agouti gene-related protein systems

1998 • 687 citations

Hypocretin (orexin) activation and synaptic innervation of the locus coeruleus noradrenergic system

1999 • 587 citations

Hypothalamic Hypocretin (Orexin): Robust Innervation of the Spinal Cord

1999 • 522 citations

Synaptic Interaction between Hypocretin (Orexin) and Neuropeptide Y Cells in the Rodent and Primate Hypothalamus: A Novel Circuit Implicated in Metabolic and Endocrine Regulations

1999 • 502 citations

Hypocretin/Orexin Excites Hypocretin Neurons via a Local Glutamate Neuron—A Potential Mechanism for Orchestrating the Hypothalamic Arousal System

2002 • 459 citations

Interaction between the Corticotropin-Releasing Factor System and Hypocretins (Orexins): A Novel Circuit Mediating Stress Response

2004 • 445 citations

Heterogeneity in the neuropeptide Y-containing neurons of the rat arcuate nucleus: GABAergic and non-GABAergic subpopulations

1997 • 298 citations

Leptin Receptor‐ and STAT3‐Immunoreactivities in Hypocretin/Orexin Neurones of the Lateral Hypothalamus¹

1999 • 226 citations

Regulation of orexin neurons by the monoaminergic and cholinergic systems

2003 • 222 citations

Serotonergic Regulation of the Orexin/Hypocretin Neurons through the 5-HT_1AReceptor

2004 • 190 citations

Melanin concentrating hormone depresses synaptic activity of glutamate and GABA neurons from rat lateral hypothalamus

2001 • 187 citations

Brain Uncoupling Protein 2: Uncoupled Neuronal Mitochondria Predict Thermal Synapses in Homeostatic Centers

1999 • 177 citations

Neural basis of orexigenic effects of ghrelin acting within lateral hypothalamus

2003 • 140 citations

Reciprocal synaptic relationships between orexin- and melanin-concentrating hormone-containing neurons in the rat lateral hypothalamus: a novel circuit implicated in feeding regulation

2002 • 121 citations

Fasting Activates the Nonhuman Primate Hypocretin (Orexin) System and Its Postsynaptic Targets

2003 • 113 citations

The floating blueprint of hypothalamic feeding circuits

2004 • 99 citations

Introduction to Synaptic Circuits

2004 • 93 citations

The cellular effects of estrogens on neuroendocrine tissues

1988 • 85 citations

The Hypothalamic Melanocortin System Stimulates the Hypothalamo-Pituitary-Adrenal Axis in vitro and in vivo in Male Rats

2002 • 68 citations

Estrogen responsive cells in the arcuate nucleus of the rat contain glutamic acid decar☐ylase (GAD): an electron microscopic immunocytochemical study

1985 • 39 citations

Melanin-Concentrating Hormone

2006 • 39 citations

Phospholipase C-β1 Is Present in the Botrysome, an Intermediate Compartment-Like Organelle, and Is Regulated by Visual Experience in Cat Visual Cortex

1997 • 33 citations

Roles of orexins in the regulation of feeding and arousal

2002 • 27 citations