Targeting Peptides Transiently Block a Mitochondrial Channel

Import of proteins into mitochondria. Cytochrome b2 and cytochrome c peroxidase are located in the intermembrane space of yeast mitochondria.

1982 • 1,152 citations

Mitochondrial targeting sequences may form amphiphilic helices.

1986 • 1,019 citations

A protein-conducting channel in the endoplasmic reticulum

1991 • 613 citations

Mitochondrial proteins essential for viability mediate protein import into yeast mitochondria

1991 • 278 citations

Selectivity Changes in Site-Directed Mutants of the VDAC Ion Channel: Structural Implications

1990 • 269 citations

The mitochondrial megachannel is the permeability transition pore

1992 • 262 citations

Signal peptides open protein-conducting channels in E. coli

1992 • 216 citations

Mitochondrial channel activity studied by patch-clamping mitoplasts

1989 • 206 citations

Mitochondrial benzodiazepine receptor linked to inner membrane ion channels by nanomolar actions of ligands.

1993 • 198 citations

Identification of intermediates in the pathway of protein import into chloroplasts and their localization to envelope contact sites.

1993 • 179 citations

MAS6 encodes an essential inner membrane component of the yeast mitochondrial protein import pathway

1993 • 171 citations

Structure of the outer mitochondrial membrane: ordered arrays of porelike subunits in outer-membrane fractions from neurospora crassa mitochondria

1982 • 162 citations

A membrane fusion strategy for single‐channel recordings of membranes usually non‐accessible to patch‐clamp pipette electrodes

1987 • 156 citations

Electrophysiology of the inner mitochondrial membrane

1994 • 147 citations

The protein import machine of the mitochondrial inner membrane

1994 • 121 citations

Modulation of inner mitochondrial membrane channel activity

1992 • 97 citations

The effect of antimycin A on mouse liver inner mitochondrial membrane channel activity.

1992 • 95 citations

Molecular Design of the Voltage-Dependent, Anion-Selective Channel in the Mitochondrial Outer Membrane

1995 • 94 citations

On the transfer of integral proteins into membranes.

1987 • 92 citations

Antibacterial peptides and mitochonrial presequences affect mitochonrial coupling, respiration and protein import

1994 • 91 citations

The polytopic mitochondrial inner membrane proteins MIM17 and MIM23 operate at the same preprotein import site

1994 • 89 citations

Ultrastructural and biochemical studies of mitoplasts and outer membranes derived from French-pressed mitochondria

1977 • 70 citations

Mas6p can be cross-linked to an arrested precursor and interacts with other proteins during mitochondrial protein import.

1993 • 65 citations

A synthetic presequence reversibly inhibits protein import into yeast mitochondria.

1990 • 64 citations

Blockade of a mitochondrial cationic channel by an addressing peptide: An electrophysiological study

1989 • 58 citations

Comparison of mitochondrial cationic channels in wild-type and porin-deficient mutant yeast

1990 • 49 citations

Multiple conductance channel activity of wild-type and voltage-dependent anion-selective channel (VDAC)-less yeast mitochondria

1995 • 49 citations

Properties of the mitochondrial peptide-sensitive cationic channel studied in planar bilayers and patches of giant liposomes

1992 • 44 citations

A peptide‐sensitive channel of large conductance is localized on mitochondrial outer membrane

1991 • 44 citations

Molecular Biology of Mitochondrial Transport Systems

1994 • 37 citations

Basic peptides can be imported into yeast mitochondria by two distinct targeting pathways. Involvement of the peptide-sensitive channel of the outer membrane.

1994 • 33 citations

Reversible and irreversible effects of basic peptides on the mitochondrial cationic channel

1994 • 28 citations

The use of chemical cross-linking to identify proteins that interact with a mitochondrial presequence.

1994 • 15 citations

A 28 kDa mitochondrial protein is radiolabelled by crosslinking with a ¹²³I‐labelled presequence

1991 • 6 citations