Nucleic acids and cancer

Molecular Structure of Nucleic Acids: A Structure for Deoxyribose Nucleic Acid

1953 • 12,496 citations

On the Origin of Cancer Cells

1956 • 12,141 citations

STUDIES ON THE CHEMICAL NATURE OF THE SUBSTANCE INDUCING TRANSFORMATION OF PNEUMOCOCCAL TYPES

1944 • 3,183 citations

On Respiratory Impairment in Cancer Cells

1956 • 2,963 citations

Genetical Implications of the Structure of Deoxyribonucleic Acid

1953 • 2,087 citations

The Age Distribution of Cancer and a Multi-stage Theory of Carcinogenesis

1954 • 1,475 citations

Genetical Implications of the Structure of Deoxyribonucleic Acid

2017 • 1,338 citations

The age distribution of cancer and a multi-stage theory of carcinogenesis

2004 • 1,306 citations

The Chemical Basis of Heredity

1957 • 1,044 citations

The Significance of Pneumococcal Types

1928 • 1,043 citations

The significance of penumococcal types

1966 • 992 citations

LIVER MICROSOMES

1956 • 919 citations

GENETIC EXCHANGE IN SALMONELLA

1952 • 822 citations

Infectivity of Ribonucleic Acid from Tobacco Mosaic Virus

1956 • 810 citations

THE ENDOPLASMIC RETICULUM

1956 • 775 citations

Studies on the Chemical Nature of the Substance Inducing Transformation of Pneumococcal Types

2017 • 770 citations

Cancer--A Biological Approach: I. The Processes Of Control. II. The Significance of Somatic Mutation

1957 • 732 citations

PURIFICATION OF A NERVE-GROWTH PROMOTING PROTEIN FROM THE MOUSE SALIVARY GLAND AND ITS NEURO-CYTOTOXIC ANTISERUM

1960 • 692 citations

A Two-stage Theory of Carcinogenesis in Relation to the Age Distribution of Human Cancer

1957 • 553 citations

On Respiratory Impairment in Cancer Cells

1956 • 511 citations

Mode of Action of Penicillin

1957 • 460 citations

Cancer--A Biological Approach: III. Viruses Associated with Neoplastic Conditions. IV. Practical Applications

1957 • 459 citations

Enzymatic and Metabolic Adaptations in Animals

1956 • 457 citations

CONTROL OF PYRIMIDINE BIOSYNTHESIS IN ESCHERICHIA COLI BY A FEED-BACK MECHANISM

1956 • 444 citations

The Chemical Production of Mutations

1947 • 437 citations

Microsomal particles and protein synthesis

1958 • 391 citations

CODES WITHOUT COMMAS

1957 • 328 citations

The Carcinogenic Aminoazo Dyes

1953 • 325 citations

Electronic Structure and Carcinogenic Activity of Aromatic Molecules New Developments

1955 • 301 citations

Electron microscopy of tumor cells and tumor viruses; a review.

1958 • 300 citations

A MODEL OF GROWTH AND GROWTH CONTROL IN MATHEMATICAL TERMS

1957 • 283 citations

BACTERIAL PERMEASES

1957 • 257 citations

Chemistry of Insulin

1959 • 249 citations

The control of cell division; a review. I. General mechanisms.

1957 • 223 citations

Cellular mechanisms in differentiation and growth

1957 • 223 citations

Subcellular Particles.

1960 • 221 citations

ROLE OF CHROMOSOMES IN CANCEROGENESIS, AS STUDIED IN SERIAL TISSUE CULTURE OF MAMMALIAN CELLS

1958 • 220 citations

Antigenicity of Pooled Human Malignant and Normal Tissues by Cyto-Immunological Technique: Presence of an Insoluble, Heat-Labile Tumor Antigen

1957 • 212 citations

Advances in Chemotherapy of Cancer in Man

1956 • 193 citations

The elementary units of heredity.

1956 • 190 citations

The induction of neoplasms with a substance released from mouse tumors by tissue culture

1957 • 177 citations

ROLE OF CHROMOSOMES IN CANCEROGENESIS, AS STUDIED IN SERIAL TISSUE CULTURE OF MAMMALIAN CELLS

1958 • 176 citations

Serial Transplantation of Embryonic Nuclei

1956 • 171 citations

Carcinogenesis and Tumor Pathogenesis

1954 • 165 citations

Oxidative Metabolism of Neoplastic Tissues

1955 • 165 citations

Developmental Cytology.

1960 • 162 citations

CONTROL BY URACIL OF FORMATION OF ENZYMES REQUIRED FOR OROTATE SYNTHESIS

1957 • 162 citations

DIRECT EVIDENCE FOR NUCLEAR SYNTHESIS OF CYTOPLASMIC RIBOSE NUCLEIC ACID

1955 • 153 citations

FURTHER EVIDENCE FAVORING THE CONCEPT OF THE STEM CELL IN ASCITES TUMORS OF RATS

1956 • 146 citations

WAVELENGTH DEPENDENCE OF MUTATION PRODUCTION IN THE ULTRAVIOLET WITH SPECIAL EMPHASIS ON FUNGI

1941 • 143 citations

Nuclear Differentiation and Functional Morphology of Chromosomes

1956 • 137 citations

ISOLATION OF INFECTIOUS DEOXYRIBONUCLEIC ACID FROM SE POLYOMA-INFECTED TISSUE CULTURES

1959 • 137 citations

The Molecular Basis of Evolution

1960 • 137 citations

The control of cell division: a review. II. Special mechanisms.

1958 • 135 citations

The significance of mutation in relation to the origin of tumors: a review.

1955 • 129 citations

The Role of Viruses in the Production of Cancer

1954 • 127 citations

Genetic transformation II. The significance of damage to the DNA molecule

1959 • 127 citations

The inhibition by glutamine of glutamyl transferase formation in cultures of human cells

1958 • 125 citations

The Physical Basis of Heredity.

1920 • 123 citations

Die Erzeugung von Mutationen des Tabakmosaikvirus durch chemische Behandlung seiner Nucleins�urein vitro

1958 • 92 citations

ENZYMATIC SYNTHESIS OF DEOXYRIBONUCLEIC ACID. V. CHEMICAL COMPOSITION OF ENZYMATICALLY SYNTHESIZED DEOXYRIBONUCLEIC ACID

1958 • 91 citations

IMMUNOSELECTION OF POLYPLOIDS FROM PREDOMINANTLY DIPLOID CELL POPULATIONS

1956 • 87 citations

Enzymic formation of 6-mercaptopurine ribotide

1957 • 86 citations

CONVERSION OF URACIL DEOXYRIBOSIDE TO THYMIDINE OF DEOXYRIBONUCLEIC ACID

1956 • 84 citations

Studies in Synthesis of Deoxyribonucleic Acid: Radiobiochemical Lesion in Animal Cells

1958 • 83 citations

THE ELECTRON MICROSCOPY OF NORMAL AND MALIGNANT CELLS

1956 • 82 citations

Indirect induction of lymphomas in irradiated mice. IV. Genetic evidence of the origin of the tumor cells from the thymic grafts.

1956 • 79 citations

The Physical Basis of Heredity

1920 • 77 citations

ELECTRON MICROSCOPE STUDIES OF ASCITES TUMOR CELLS

1956 • 76 citations

The Action of Radiation on Mammalian Cells

1960 • 74 citations

RECENT CONTRIBUTIONS TO THE PHARMACOLOGY OF BIS(2-HALOETHYL) AMINES AND SULFIDES

1950 • 73 citations

Electronic Configuration and Carcinogenesis

1953 • 71 citations

The relative reactivities of deoxyribonucleotides and of the bases of DNA towards alkylating agents

1957 • 68 citations

Separation of Human Placental Estrogen-sensitive Transhydrogenase from Estradiol-17β Dehydrogenase

1959 • 67 citations

Some biochemical characteristics of morphologically separable cancers.

1956 • 65 citations

ETIOLOGY OF AVIAN LEUKOSIS

1957 • 65 citations

CHEMISTRY OF THE ABNORMAL HUMAN HAEMOGLOBINS

1959 • 64 citations

A PROCEDURE FOR DETECTING CARRIERS OF GALACTOSEMIA

1959 • 62 citations

Indirect induction of lymphomas in irradiated mice. I. Tumor incidence and morphology in mice bearing nonirradiated thymic grafts.

1956 • 61 citations

STUDIES OF ERYTHROPOIETIN: THE HORMONE REGULATING RED CELL PRODUCTION

1959 • 61 citations

Enzyme Studies with Mutant Mammalian Cells

1960 • 61 citations

The biochemical approach to the cancer problem.

1958 • 61 citations

BIOLOGICAL ASPECTS OF CANCER

1959 • 60 citations

Metabolic effects of 6-thioguanine. I. Studies on thioguanine-resistant and-sensitive Ehrlich ascites cells.

1958 • 59 citations

The physical chemistry of deoxyribonucleic acids

1957 • 59 citations

Effect of Radiation on DNA Synthesis in Mammalian Cells

1957 • 59 citations

Viral etiology of spontaneous mouse leukemia; a review.

1958 • 57 citations

On the Mechanism of Cancer Induction by Ultraviolet Radiation

1950 • 57 citations

Differences between cancers in terms of evolution of drug resistance.

1956 • 55 citations

THE MECHANISM OF CHEMICAL CARCINOGENESIS

1958 • 54 citations

The Milk Agent in the Origin of Mammary Tumors in Mice

1953 • 53 citations

Carcinogenesis; a facet of living processes.

1954 • 53 citations

Quantitative morphological studies on the livers and liver homogenates of rats fed 2-methyl- or 3 -methyl-4-dimethylaminoazobenzene.

1953 • 52 citations

The Biochemistry of Cancer

1955 • 52 citations

Materials for the Biophysical and Biochemical Study of Cell Division

1956 • 50 citations

Skin metaplasia in vitro induced by brief exposure to vitamin A.

1955 • 50 citations

Organization in benign and malignant cells.

1959 • 49 citations

ROUTES OF NATURAL INFECTION IN AVIAN LYMPHOMATOSIS

1957 • 49 citations

CHEMOTHERAPY OF CHORIOCARCINOMA AND RELATED TROPHOBLASTIC TUMORS IN WOMEN

1959 • 49 citations

A mechanism of resistance to 8-azaguanine. II. Studies with experimental neoplasms.

1959 • 49 citations

Observations on the Rous Virus; Integrated Electron Microscopical and Cytochemical Studies of Fluorocarbon Purified Preparations

1958 • 46 citations

The Action of Ionizing Radiations on Biological Materials: Facts and Theories

1956 • 45 citations

The Biosynthesis of Protein

1957 • 45 citations

PROTEIN BIOSYNTHESIS

1960 • 44 citations

INCORPORATION OF H ³ CYTIDINE AND H ³ THYMIDINE INTO GIANT CHROMOSOMES OF DROSOPHILA DURING PUFF FORMATION

1959 • 44 citations

Reactions of C14-labeled carcinogenic azo dyes with rat liver proteins

1957 • 43 citations

Control of Enzyme Activity

1976 • 43 citations

A discussion of the mechanism of action of steroid hormones.

1957 • 42 citations

The biosynthesis of protein.

1957 • 41 citations

THE GENE AND CELL DIFFERENTIATION

1960 • 41 citations

Chromatographic Fractionation of Deoxyribonucleic Acids with Special Emphasis on the Transforming Factor of Pneumococcus

1956 • 40 citations

Tumor Viruses

1955 • 40 citations

Ultrastructure of Viruses of Myeloblastosis and Erythroblastosis Isolated from Plasma of Leukemic Chickens.

1958 • 40 citations

STUDIES ON THE NATURE AND BIOLOGICAL PROPERTIES OF A TRANSMISSIBLE AGENT CAUSING LEUKEMIA FOLLOWING INOCULATION INTO NEWBORN MICE

1957 • 39 citations

A METHOD OF SELECTING FOR AUXOTROPHIC MUTANTS OF H<scp>E</scp>L<scp>A</scp> CELLS

1960 • 38 citations

Soluble liver h proteins during hepatocarcinogenesis by aminoazo dyes and 2-acetylaminofluorene in the rat.

1958 • 38 citations

Ciba Foundation Symposium ‐ Carcinogenesis: Mechanisms of Action

1959 • 38 citations

Induction of Mouse Leukæmia with Purified Nucleic Acid Preparations

1957 • 37 citations

Protein Biosynthesis

1959 • 37 citations

Nucleic Acid of the Rabbit Papilloma Virus Protein

1942 • 36 citations

ASPECTS OF ENDOCRINE CARCINOGENESIS

1958 • 33 citations

Biosynthetic incorporation of metabolite analogues.

1958 • 33 citations

Metabolic Antagonists

1958 • 33 citations

TRANSMISSIBLE TUMORS OF THE FOWL

1933 • 32 citations

Amination of uridine nucleotides to cytidine nucleotides by soluble mammalian enzymes: Role of glutamine and guanosine nucleotides

1958 • 31 citations

COCARCINOGENESIS

1958 • 31 citations

Some Introductory Remarks on the Cellular Basis of Differentiation

1968 • 31 citations

Some Introductory Remarks on the Cellular Basis of Differentiation

1953 • 31 citations

BIOLOGICAL ASPECTS OF CANCER

1958 • 31 citations

The fallacy of the concept of virus masking: a review.

1956 • 30 citations

Biochemistry of Cancer

1958 • 30 citations

Active transport of O-diazoacetyl-L-serine and 6-diazo-5-oxo-L-norleucine in Ehrlich ascites carcinoma.

1957 • 29 citations

Infection with the Rous sarcoma virus in vitro.

1958 • 29 citations

Adaptive enzymes and feedback mechanisms.

1959 • 27 citations

The Leukemias: Etiology, Pathophysiology, and Treatment

1958 • 27 citations

A comparative view of the chromosome.

1959 • 26 citations

Mechanisms of drug action in leukemia

1960 • 26 citations

Ionizing Radiations and Cancer

1954 • 25 citations

The Structure of Proteins

1959 • 25 citations

NUCLEAR AND ALLIED RADIATIONS AND THE INCIDENCE OF LEUKAEMIA IN MAN

1958 • 24 citations

Metabolism of Nucleic Acids

1962 • 23 citations

Biochemistry of Carcinogenesis

1959 • 22 citations

Metabolic activity of salivary gland chromosomes in Diptera

1956 • 22 citations

Biochemical uniformity and heterogeneity in cancer tissue (further discussion).

1956 • 21 citations

An appraisal of tumor-virus problems

1958 • 21 citations

VIRUSES, GENES, AND CELLS

1957 • 21 citations

A physiological study on the nature of autonomous growth in neoplastic plant cells.

1957 • 21 citations

A Quantitative Biological Test Sensitive to Low Doses of Ionizing Radiations

1954 • 21 citations

VII. NEW APPROACHES TO THE PROBLEM OF EMBRYONIC INDUCTION

1957 • 18 citations

The Ontogeny of Divergent Metabolic Patterns in Cells of Identical Genotype

1956 • 18 citations

The life history of the cell.

1957 • 17 citations

THE ARRANGEMENT OF PURINE AND PYRIMIDINE NUCLEOTIDES IN TOBACCO MOSAIC VIRUS NUCLEIC ACID

1959 • 17 citations

SOME ASPECTS OF DRUG RESISTANCE IN NEOPLASMS

1958 • 17 citations

GENETIC CONCEPT FOR THE ORIGIN OF CANCER: HISTORICAL REVIEW

1958 • 16 citations

The Cytology of the Tumor Cell in the Rous Chicken Sarcoma

1939 • 14 citations

Induction of Neoplasms by Injection of Tumor Chromatin<xref ref-type="fn" rid="fn1">1</xref>, <xref ref-type="fn" rid="fn2">2</xref>

1955 • 14 citations

Genetic, hormonal and age factors in susceptibility and resistance to tumor-inducing viruses.

1957 • 14 citations

The Physiopathology of Cancer

1954 • 13 citations

An appraisal of the concepts of endocrine influence on the etiology, pathogenesis, and control of abnormal and neoplastic growth.

1957 • 12 citations

CLONAL DERIVATION OF VIRUSES

1957 • 12 citations

An Intestinal Carcinoma in Mice Following Injection of Herring-Sperm Deoxyribonucleic Acid

1959 • 12 citations

The Specific Action of Azaserine on Enzymes Concerned with Purine Biosynthesis

1957 • 12 citations

Viruses as a cause of cancer.

1960 • 10 citations

The national cancer chemotherapy program

1958 • 9 citations

Developmental Physiology

1955 • 8 citations

The radiobiology of the cancer cell.

1958 • 8 citations

Studies on Resistance to Folic Acid Antagonists

1957 • 8 citations

Nucleic acid as the carrier of viral activity.

1958 • 8 citations

Zur Frage der Beteiligung von Nucleins�uren an der chemischen Zusammensetzung des leuk�mogenen Agens aus filtrierbaren M�usetumoren

1957 • 6 citations

Biochemistry of Cancer

1956 • 5 citations

Carcinogenesis, Radiation

2020 • 5 citations

Hereditary aspects of disease.

1959 • 5 citations

The Relation Between the Incidence and Incubation Period of Cancer in Man.

1944 • 4 citations

509 – Viruses as the cause of cancer

2000 • 3 citations