Human ITCH Is a Coregulator of the Hematopoietic Transcription Factor NF-E2

pEF-BOS, a powerful mammalian expression vector

1990 • 1,641 citations

Multilineage gene expression precedes commitment in the hemopoietic system.

1997 • 757 citations

The two-hybrid system: an assay for protein-protein interactions

1994 • 649 citations

Construction of plasmids that expressE.coli β-galactosidase in mammalian cells

1989 • 458 citations

Structure of the WW domain of a kinase-associated protein complexed with a proline-rich peptide

1996 • 426 citations

The itchy locus encodes a novel ubiquitin protein ligase that is disrupted in a18H mice

1998 • 328 citations

Recognition and Ubiquitination of Notch by Itch, a Hect-type E3 Ubiquitin Ligase

2000 • 321 citations

Regulation of Transcription by Ubiquitination without Proteolysis

2000 • 292 citations

From Src Homology domains to other signaling modules: proposal of the `protein recognition code'

1998 • 232 citations

Atrophin-1, the DRPLA Gene Product, Interacts with Two Families of WW Domain-Containing Proteins

1998 • 165 citations

Yeast RSP5 and Its Human Homolog hRPF1 Potentiate Hormone-Dependent Activation of Transcription by Human Progesterone and Glucocorticoid Receptors

1996 • 160 citations

Molecular structure and chromosomal mapping of the human homolog of the agouti gene.

1994 • 160 citations

Level of ubiquitinated histone H2B in chromatin is coupled to ongoing transcription

1990 • 153 citations

Molecular genetic characterization of six recessive viable alleles of the mouse agouti locus.

1995 • 125 citations

Localization of the Congenital Dyserythropoietic Anemia II Locus to Chromosome 20q11.2 by Genomewide Search

1997 • 98 citations

Molecules in focus The NF-E2 transcription factor

1998 • 87 citations

Physical and Functional Interactions between the Transactivation Domain of the Hematopoietic Transcription Factor NF-E2 and WW Domains

1998 • 66 citations

Interaction of WW Domains with Hematopoietic Transcription Factor p45/NF-E2 and RNA Polymerase II

1997 • 62 citations

A HECT domain ubiquitin ligase closely related to the mammalian protein WWP1 is essential for Caenorhabditis elegans embryogenesis

2000 • 41 citations

A transient increase in histone H2A ubiquitination is coincident with the onset of erythroleukemic cell differentiation

1988 • 19 citations