Effects of antioxidant enzyme overexpression on the invasive phenotype of hamster cheek pouch carcinoma cells

Metastasis: Quantitative Analysis of Distribution and Fate of Tumor Emboli Labeled With <sup>125</sup>I-5-Iodo-2′ -deoxyuridine<xref ref-type="fn" rid="FN2">2</xref><xref ref-type="fn" rid="FN3">3</xref>

1970 • 990 citations

An assay for superoxide dismutase activity in mammalian tissue homogenates

1989 • 702 citations

BIOCHEMICAL INTERACTIONS OF TUMOR CELLS WITH THE BASEMENT MEMBRANE

1986 • 693 citations

E-cadherin expression in squamous cell carcinomas of head and neck: inverse correlation with tumor dedifferentiation and lymph node metastasis.

1991 • 536 citations

Secretion of metalloproteinases by stimulated capillary endothelial cells. II. Expression of collagenase and stromelysin activities is regulated by endogenous inhibitors.

1986 • 531 citations

Increased manganese superoxide dismutase expression suppresses the malignant phenotype of human melanoma cells.

1993 • 479 citations

Role of the alpha v beta 3 integrin in human melanoma cell invasion.

1992 • 414 citations

Phenotypic changes induced in human breast cancer cells by overexpression of manganese-containing superoxide dismutase.

1995 • 244 citations

A simple quantitative assay for studying the invasive potential of high and low human metastatic variants

1987 • 243 citations

Suppression of the malignant phenotype of human glioma cells by overexpression of manganese superoxide dismutase

1997 • 238 citations

Loss of heterozygosity for loci on the long arm of chromosome 6 in human malignant melanoma.

1991 • 233 citations

Characterization of chromosomal anomalies in human breast cancer

1990 • 218 citations

Human Mitochondrial Manganese Superoxide Dismutase Polymorphic Variant Ile58Thr Reduces Activity by Destabilizing the Tetrameric Interface^,

1996 • 182 citations

Coexpression of Vimentin and Keratins by Human Melanoma Tumor Cells: Correlation With Invasive and Metastatic Potential

1992 • 174 citations

Manganese-containing superoxide dismutase overexpression causes phenotypic reversion in SV40-transformed human lung fibroblasts.

1996 • 158 citations

Overexpression of manganese superoxide dismutase in DU145 human prostate carcinoma cells has multiple effects on cell phenotype

1998 • 150 citations

The 72 kDa type IV collagenase is modulated via differential expression of alpha v beta 3 and alpha 5 beta 1 integrins during human melanoma cell invasion.

1993 • 147 citations

Transfection and Expression of MnSOD cDNA Decreases Tumor Malignancy of Human Oral Squamous Carcinoma SCC-25 Cells

1997 • 140 citations

Suppression of fibrosarcoma metastasis by elevated expression of manganese superoxide dismutase.

1994 • 139 citations

SOD2: A new type of tumor‐suppressor gene?

1992 • 132 citations

Expression of manganese superoxide dismutase promotes cellular differentiation

1994 • 128 citations

Redox Gene Therapy Protects Human IB-3 Lung Epithelial Cells Against Ionizing Radiation-Induced Apoptosis

1998 • 125 citations

Evidence that the process of murine melanoma metastasis is sequential and selective and contains stochastic elements.

1986 • 116 citations

Alteration of endogenous glutathione peroxidase, manganese superoxide dismutase, and glutathione transferase activity in cells transfected with a copper-zinc superoxide dismutase expression vector. Explanation for variations in paraquat resistance.

1990 • 112 citations

Immunohistochemical localization of antioxidant enzymes in adult Syrian hamster tissues and during kidney development.

1990 • 103 citations

Superoxide Dismutase Activity of Normal Murine Liver, Regenerating Liver, and H6 Hepatoma<xref ref-type="fn" rid="FN2">2</xref>

1978 • 94 citations

Superoxide dismutase in SAS human tongue carcinoma cell line is a factor defining invasiveness and cell motility.

1995 • 93 citations

Effect of reactive oxygen intermediates on the in vitro invasive capacity of tumor cells and liver metastasis in mice

1993 • 75 citations

Correlation between the loss of the transformed phenotype and an increase in superoxide dismutase activity in a revertant subclone of sarcoma virus-infected mammalian cells.

1982 • 65 citations

Superoxide radical potentiates invasive capacity of rat ascites hepatoma cells in vitro

1986 • 63 citations

Sinusoidal endothelium release of hydrogen peroxide enhances very late antigen-4-mediated melanoma cell adherence and tumor cytotoxicity during interleukin-1 promotion of hepatic melanoma metastasis in mice

1997 • 54 citations

Adenovirus-mediated manganese superoxide dismutase gene transfer to hamster cheek pouch carcinoma cells.

1997 • 47 citations

Manganese superoxide dismutase expression inhibits soft agar growth in JB6 clone41 mouse epidermal cells

1997 • 47 citations

Suppressive effect of recombinant human Cu, Zn‐superoxide dismutase on lung metastasis of murtne tumor cells

1994 • 47 citations

Lowered level of translatable messenger RNAs for manganese superoxide dismutase in human fibroblasts transformed by SV 40

1985 • 44 citations

Superoxide dismutase and catalase levels during estrogen-induced renal tumorigenesis, in renal tumors and their autonomous variants in the Syrian hamster

1991 • 42 citations

An Epidermoid Carcinoma Cell Line Derived From Hamster 7,12- Dimethylbenz[<italic>a</italic>]anthracene-Induced Buccal Pouch Tumors<xref ref-type="fn" rid="FN2">2</xref>

1983 • 41 citations

Suppression of intracellular Cu-Zn SOD results in enhanced motility and metastasis of Meth A sarcoma cells

1997 • 40 citations

Cell-mediated degradation of type IV collagen and gelatin films is dependent on the activation of matrix metalloproteinases

1992 • 34 citations

Immunohistochemical localization of glutathione-S-transferase and glutathione peroxidase in adult Syrian hamster tissues and during kidney development.

1991 • 34 citations

Membrane invasion culture system (MICS).

1984 • 28 citations

Superoxide Dismutase Activity During Dimethylhydrazine Colon Carcinogenesis and the Effects of Cholic Acid and Indole

1988 • 27 citations

Electrophoretic analysis of proteins associated with tumor cell invasion

1994 • 15 citations

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