Increased manganese superoxide dismutase expression suppresses the malignant phenotype of human melanoma cells.

PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT

1951 • 319,299 citations

Detection of specific sequences among DNA fragments separated by gel electrophoresis

1975 • 33,059 citations

A genetic model for colorectal tumorigenesis

1990 • 11,800 citations

Hydroperoxide metabolism in mammalian organs.

1979 • 5,821 citations

Reactive oxygen intermediates as apparently widely used messengers in the activation of the NF-kappa B transcription factor and HIV-1.

1991 • 3,819 citations

ras GENES

1987 • 3,818 citations

Bcl-2 is an inner mitochondrial membrane protein that blocks programmed cell death

1990 • 3,817 citations

Prooxidant States and Tumor Promotion

1985 • 2,541 citations

Handbook of methods for oxygen radical research

1987 • 2,395 citations

Molecular themes in oncogenesis

1991 • 1,663 citations

Quantitation of mRNA by the polymerase chain reaction.

1989 • 1,648 citations

Mitochondrial Membrane Potential in Living Cells

1988 • 1,010 citations

Induction of Manganous Superoxide Dismutase by Tumor Necrosis Factor: Possible Protective Mechanism

1988 • 933 citations

Monitoring of relative mitochondrial membrane potential in living cells by fluorescence microscopy.

1981 • 913 citations

Cooperation between oncogenes

1991 • 792 citations

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1991 • 775 citations

Tumor Mitochondria and the Bioenergetics of Cancer Cells

2015 • 720 citations

Monoclonal antibodies specific for melanocytic tumors distinguish subpopulations of melanocytes.

1986 • 531 citations

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1993 • 518 citations

Introduction of a Normal Human Chromosome 11 into a Wilms' Tumor Cell Line Controls Its Tumorigenic Expression

1987 • 407 citations

Tumorigenicity in Human Melanoma Cell Lines Controlled by Introduction of Human Chromosome 6

1990 • 333 citations

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1990 • 266 citations

Inhibition of Tumor Promotion by a Biomimetic Superoxide Dismutase

1983 • 256 citations

Loss of heterozygosity for loci on the long arm of chromosome 6 in human malignant melanoma.

1991 • 233 citations

The assessment of proliferating cell nuclear antigen (PCNA) immunostaining in primary gastrointestinal lymphomas and its relationship to histological grade, S + G2 + M phase fraction (flow cytometric analysis) and prognosis

1991 • 220 citations

Synthesis and processing of the precursor for human mangano-superoxide dismutase

1989 • 199 citations

Oxygen-Reactive Species and Antioxidant Responses during Development: The Metabolic Paradox of Cellular Differentiation

1991 • 172 citations

Expression of membrane interleukin 1 by fibroblasts transfected with murine pro-interleukin 1 alpha cDNA.

1988 • 171 citations

Multiple transforming growth factor-beta-inducible elements regulate expression of the plasminogen activator inhibitor type-1 gene in Hep G2 cells.

1991 • 158 citations

SOD2: A new type of tumor‐suppressor gene?

1992 • 132 citations

Modifiers of free radicals inhibit in vitro the oncogenic actions of x-rays, bleomycin, and the tumor promoter 12-O-tetradecanoylphorbol 13-acetate.

1983 • 126 citations

Cell differentation, aging and cancer: The possible roles of superoxide and superoxide dismutases

1980 • 126 citations

Neoplastic transformation is associated with coordinate induction of nuclear and cytoplasmic oxidative phosphorylation genes

1990 • 123 citations

Active oxygen induced DNA strand breakage and poly ADP-ribosylation in promotable and non-promotable JB6 mouse epidermal cells

1988 • 119 citations

Sublocalization of the gene encoding manganese superoxide dismutase (MnSOD/SOD2) to 6q25 by fluorescence in Situ hybridization and somatic cell hybrid mapping

1992 • 105 citations

Immunohistochemical localization of antioxidant enzymes in adult Syrian hamster tissues and during kidney development.

1990 • 103 citations

The retinoblastoma gene and cell growth control

1990 • 91 citations

Determination of proliferating fractions in malignant melanomas by anti‐PCNA/cyclin monoclonal antibody

1991 • 85 citations

The role of superoxide dismutase and gene amplification in carcinogenesis

1984 • 76 citations

Superoxide dismutase induces differentiation of friend erythroleukemia cells

1989 • 67 citations

Fte-1, a v-fos transformation effector gene, encodes the mammalian homologue of a yeast gene involved in protein import into mitochondria.

1992 • 56 citations

Superoxide dismutase induces differentiation in microplasmodia of the slime mold Physarum polycephalum

1988 • 51 citations

Manganese superoxide dismutase: Nucleotide and deduced amino acid sequence of a cDNA encoding a new human transcript

1990 • 46 citations

Induction of manganese superoxide dismutase in cultured human trophoblast during in vitro differentiation

1992 • 42 citations